Clinical trials: Asthma Acute
Bronchial Asthma
REspiratory diSEAse cohoRt Studies of CHinese Medicine for Asthma (RESEARCH- Asthma)
The purpose of this study is to define the standard use of TCM treatment regimen as the TCM cohort group and the non-TCM cohort group of those who use conventional Western medicine treatment without the standard TCM treatment…
- Trial name
- NCT06373692
- Where
- China
- Volunteers
- 1,508 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Asthma, Acute Asthma
Budesonide for Emergency Treatment of Acute Wheezing in Children
The purpose of this study is to determine if adding nebulized budesonide to the systemic steroid for treatment of acute wheezing has any additive benefit in the emergency room.
- Trial name
- NCT00733317
- Testing
- 0.5 mg/ml budesonide nebules, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kecioren Education and Training Hospital
Asthma
Validation of Structured Light Plethysmography: Asthma
Validation of Structured Light Plethysmography (SLP) in patients with asthma, in patients with acute asthma; an observational study in healthy participants and during patients' clinical investigation of broncho-reversibility in…
- Trial name
- SLPBD (NCT02543333)
- Where
- 2 sites in United Kingdom
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Pneumacare Ltd
Asthma
Trial for the Treatment of Acute Asthma in Wheezy Pre-school Aged Children
To determine if treatment of pre-school children with a history of wheeze who present to an Emergency Department with an acute wheezing episode with azithromycin for 5 days will resolve their symptoms more quickly, will require…
- Trial name
- NCT01008761
- Testing
- Azithromycin
- Where
- 2 sites in Canada
- Volunteers
- 440 people
- Sponsor
- Janielee Williamson
Asthma, Reactive Airway Disease
Single Oral Dose of Dexamethasone Versus Five Days of Prednisone in Adult Asthma
This study seeks to compare the effectiveness of a single dose of oral dexamethasone versus 5 days of oral prednisone in the treatment of mild to moderate asthma exacerbations to prevent relapse with an unscheduled return visit…
- Trial name
- NCT01241006
- Testing
- Dexamethasone, Prednisone
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- Alameda County Medical Center
Pulmonary Disease, Chronic Obstructive, Asthma
Smoking Cessation Intervention in Respiratory Inpatients
Prospective, open-label, parallel-group, 52-week trial comparing varenicline in combination with behavioral support with one session of behavioral support alone.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Asthma, Community Acquired Pneumonia
- Trial name
- NCT02922387
- Testing
- Varenicline, Behavioral support
- Volunteers
- 101 people
- Sponsor
- General Hospital of Kavala
Asthma in Children
Magnesium Sulfate in Bronchial Asthma and Acute Bronchiolitis in Children
Asthma is a prevalent disease that affects as many as334 million individuals worldwide, and is a major source of disability and premature death in children(1). Asthma affects 7.1 million children in the United States (2).
- Trial name
- NCT06955559
- Testing
- Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- Assiut University
Bronchial Asthma
A Clinical Study on the Prevention of Mild to Moderate Intermittent Asthma With Chinese Medicine Weiyang Yuping Fang
Clinical exploring study of Weiyang Yuping Decoction in preventing acute attacks of mild to moderate intermittent asthma Based on the theory of "Preventing disease from exacerbating" in Chinese medicine.
- Trial name
- NCT04522726
- Testing
- Weiyang Yuping Fang
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Wheezy Bronchitis
Intravenous Magnesium in Wheezy Bronchitis
In infants and toddlers wheezy bronchitis is a common viral disease. To relieve wheezing symptoms bronchodilators or corticosteroids are commonly used but the efficacy is not always satisfactory.
- Trial name
- NCT01383655
- Testing
- Magnesium Sulfate
- Where
- Finland
- Volunteers
- 61 people
- Sponsor
- University of Oulu
Asthma
Hypertonic Saline as Add on Therapy in Preschool Children With Acute Wheezing Attack.
To investigate the efficacy of adding Inhaled Hypertonic Saline treatment (HS) for 1-6 year old children with "asthmatic" attack presenting to Emergency Department (ED).
- Trial name
- NCT01073527
- Testing
- hypertonic saline-salbutamol combination, Normal saline-salbutamol combination
- Where
- Israel
- Volunteers
- 41 people
- Sponsor
- Wolfson Medical Center
Childhood Asthma With Status Asthmaticus
Status Asthmaticus on the PICU; Intravenous Salbutamol
Although IV salbutamol is frequently used in children in a wide range, pharmacodynamic data are scarce. To date, there is an insufficient evidence base to guide initial and subsequent dosing recommendation for its IV use in…
- Trial name
- STATIC IV (NCT03493503)
- Testing
- Salbutamol, Sodium Chloride 0.9%
- Where
- Netherlands
- Volunteers
- 58 people
- Sponsor
- Erasmus Medical Center
Asthma, Mixed Asthma With Acute Exacerbation
Asthma Self-management Via Application of Telehealth
Objectives: The disease being studied is asthma. The main objective of this study is to assess the feasibility of the recruitment goals and also the logistical issues related to use of tele-health technology in developing…
- Trial name
- asthma (NCT02017795)
- Testing
- electronic asthma action plan (eAAP), written asthma action plan (WAAP)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Dyspnea, Heart Failure
Dyspnea and Biomarkers in a Prehospital Setting
In patients presenting with acute dyspnea in a pre-hospital setting, the early and correct diagnosis may present a significant clinical challenge.
- Conditions
- Dyspnea, Heart Failure, Asthma, COPD
- Trial name
- NCT00878475
- Where
- Slovenia
- Volunteers
- 546 people
- Sponsor
- Community Healthcare Center dr. Adolf Drolc Maribor (HCM)
Asthma
Web-Based and Tailored Asthma Management Intervention (Puff City) in Teens With Asthma Attending Urban Clinics
The purpose of this study is to evaluate the Puff City web-based behavioral intervention of asthma management program in a clinical setting.
- Trial name
- PCC (NCT01757002)
- Testing
- Teens randomized to the experimental arm will receive 4 sessions plus a booster of web-based, tailored asthma management., Teens in the control group will receive generic, web-based asthma education.
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Henry Ford Health System
Asthma
A Study of Levalbuterol Tartrate HFA Inhalation Aerosol Metered Dose Inhaler (MDI) in Pediatric Subjects
This is a study of levalbuterol tartrate HFA inhalation aerosol MDI in pediatric subjects birth to ≤ 48 months of age who go to the Emergency Department (ED) or their physician's office with an acute bronchospasm.
- Trial name
- NCT02150499
- Testing
- levalbuterol tartrate HFA inhalation aerosol
- Where
- 17 sites in United States
- Volunteers
- 18 people
- Sponsor
- Sumitomo Pharma America, Inc.
Asthma
Acute Airway Vascular Smooth Muscle Effects of Inhaled Budesonide
Glucocorticosteroids recently have been shown to have non-genomic actions that are plasma membrane-mediated and do not require gene transcription and translation.
- Trial name
- NCT01219738
- Testing
- Budesonide 360ug, Budesonide 720ug, Budesonide 1440ug
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Asthma in Children
Research on the Early Warning Model of Children Asthma Acute Attack Based on Wearable Wrist Smart Device of Huami
Childhood asthma is the most common chronic respiratory disease in childhood. The essence of asthma is chronic airway inflammation and airway hyperresponsiveness.The physiological characteristics of children and adults are very…
- Trial name
- NCT05243667
- Testing
- Wearable wrist Smart Device of Huami
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Asthma
Thyroid Hormones Treatment in Asthma Exacerbation
This study will explore whether supplementation with thyroid hormones in the set-up of asthma exacerbation could improve the clinical outcomes.
- Trial name
- THINAS (NCT02086799)
- Testing
- IV thyroxin
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Asthma Acute
Use of Dupilumab in Asthma in Real-world Setting
The main objective of asthma pharmacological management in adults and teenagers is to maintain long-term control of the disease, including symptom relief, the prevention of exacerbations, the improvement of pulmonary function…
- Trial name
- DUPILUMAB (NCT07637292)
- Where
- France
- Volunteers
- 35,000 people
- Sponsor
- Hospices Civils de Lyon
Asthma
Study Evaluating the Safety and Efficacy of MN-221 as an Adjunct to Standard Therapy in Subjects Experiencing an Acute Exacerbation of Asthma
The objective of this clinical study is to examine the safety and effectiveness of intravenous MN-221 compared to placebo when administered as an adjunct to standard therapy in subjects experiencing an acute exacerbation of…
- Trial name
- NCT00838591
- Testing
- MN-221
- Where
- 15 sites in United States
- Volunteers
- 176 people
- Sponsor
- MediciNova