Clinical trials: Asthma Childhood
Pediatric Asthma
The Puerto Rico Asthma Integrated Response Program ("PR-AIR")
The purpose of this study is to adapt and deliver an evidence-based multi-level intervention to reduce asthma disparities, and that promote and improve population health in the high-burden communities of San Juan, Puerto Rico.
- Trial name
- PR-AIR (NCT05999032)
- Testing
- CASE in person version (High Intensity Package), CASE-V remote version (Low Intensity Package), CASE and HARP in person (High Intensity package)
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 480 people
- Sponsor
- Rhode Island Hospital
Atopic Dermatitis
Safety and Efficacy of Pimecrolimus Cream 1% in Atopic Disease Modification
This study consists of a 3-year double-blind phase during which patients will receive atopic dermatitis (AD) treatment either with pimecrolimus cream 1% long-term management (LTM) or with a conventional corticosteroid-based…
- Trial name
- NCT00124709
- Testing
- Pimecrolimus, Corticosteroid
- Where
- 36 sites in United States
- Volunteers
- 1,091 people
- Sponsor
- Novartis Pharmaceuticals
Childhood Asthma, Oxidative Stress
Urinary 8-isoprostane is Elevated in Acute Childhood Asthma
Oxidative stress is seen in children with asthma, but is hard to measure. The investigators exploring the utility of using a commercially available assay to measure oxidative stress in the urine in asthmatics.
- Trial name
- NCT01472471
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Stony Brook University
Asthma
The Genetics of Severe Asthma in Children
Near fatal asthma exacerbations are one of the most common causes of critical illness in children, accounting for approximately ten thousand intensive care unit (ICU) admissions per year in the United States.
- Trial name
- NCT01238432
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Asthma, Anxiety
Online Cognitive Behavior Therapy for Anxiety Related to Pediatric Asthma
Asthma is a chronic condition affecting approximately 5-15% of all Swedish children. Research has shown that asthma may be associated with increased anxiety and worry, with children who have asthma being twice as likely to…
- Trial name
- NCT06657807
- Testing
- Online CBT
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Asthma in Children
Balloon Blowing Breathing Exercise in School-age Children With Asthma.
This study were to investigate the effects of balloon blowing breathing exercise on respiratory muscle strength and asthma symptoms in school-age children with asthma.
- Trial name
- NCT04874649
- Testing
- Balloon-blowing breathing, Sustained maximal inspiration breathing
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Asthma, Asthma in Children
Wearable Auscultation Device Validation in Children
This observational clinical study is an evaluation of a diagnostic tool through comparison. Similar to a validation study, the output of the RESP device will be compared to physician auscultation, surrogated by having an…
- Conditions
- Asthma, Asthma in Children, Wheezing, Pediatric Asthma
- Trial name
- NCT06112080
- Testing
- RESP™ Biosensor
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Strados Labs, Inc.
Asthma in Children, Allergy
Advanced Multimodal Wireless Vital Signs Monitoring for Patients With Asthma and Anaphylaxis
The primary objective of this study is to assess the function and reliability of a non-invasive, skin-like electronic sensor. We hypothesize that this skin sensor will address an unmet need to wirelessly, noninvasively, and…
- Trial name
- NCT04360213
- Testing
- Advanced multimodal wireless vital signs monitor
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Northwestern University
Childhood Asthma, Community Health Workers
West Philadelphia Controls Asthma
This project uses community health workers (CHW) or lay health educators to implement asthma interventions that have been proven to work in the primary care setting and in schools.
- Trial name
- WPCA (NCT03514485)
- Testing
- Yes We Can Children's Asthma Program, School-Based Asthma Therapy, Open Airways for School Plus
- Where
- United States
- Volunteers
- 626 people
- Sponsor
- Children's Hospital of Philadelphia
Environmental Exposure, Health Behavior
The Barts Charity Children's Environmental Health Clinic
The study will be based from a newly formed NHS service, the children's environmental health service. Participants will be children with a known chronic respiratory condition.
- Conditions
- Environmental Exposure, Health Behavior, Asthma in Children, Environmental Illness
- Trial name
- BCCEHC (NCT06447974)
- Testing
- Exposure mitigations
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Asthma, Asthma in Children
AeviceMD for Pediatric Asthma Management
A wearable remote patient monitor (AeviceMD) is to be used to monitor the respiratory health of pediatric asthma patients in this pilot study.
- Conditions
- Asthma, Asthma in Children, Pediatric Asthma, Chronic Respiratory Disease
- Trial name
- APAM (NCT06321471)
- Testing
- AeviceMD
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Irina Dralyuk
Mindfulness, Chronic Disease
Tailoring Mindfulness Interventions for Families Managing Chronic Health Conditions
This is not an intervention or treatment study. It is an observational qualitative data study about tailoring a mindfulness intervention to assist families managing chronic health conditions.
- Trial name
- PEP (NCT05271851)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Asthma in Children
Asthma Clinics Helping Expand Cost Conversations
Healthcare costs are a critical barrier to U.S. families' ability to access the preventive care needed to manage their children's asthma.
- Trial name
- Asthma CHECC (NCT04669080)
- Testing
- Health care provider cost navigation training
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pediatric Asthma
Cohort Multiple Randomized Controlled Trial in Pediatric Asthma
The overarching goal of this study is to optimize pediatric asthma care and to continuously evaluate variations/innovations of the care (including transformation to remote eHealth care).
- Trial name
- CIRCUS (NCT06278662)
- Testing
- video directly observed therapy (vDOT)
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Mattienne van der Kamp
Asthma
Metabolomics in the Diagnosis and Treatment of Asthma in Children
The goal of this observational study is to learn about the metabolomic profile of blood and urine in children 12-17 years with asthma.
- Trial name
- NCT07280364
- Testing
- Standart medical treatment
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Asthma, Recurrent Cough
Spirometry and Methacholine Challenge Test in Asthmatic Children Age 3-6years
Rational: The possible contribution of methacholine challenge test via spirometry to the clinical diagnosis of young children with various respiratory symptoms, the most appropriate spirometry index, and the proper cutoff point…
- Trial name
- MCH-preschool (NCT00550758)
- Testing
- Methachoine, spirometry
- Volunteers
- 84 people
- Sponsor
- Rambam Health Care Campus
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose…
- Conditions
- Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension
- Trial name
- POPS or POP02 (NCT04278404)
- Testing
- The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Asthma in Children
Tiotropium vs. Inhaled Corticosteroids in Children With Nonatopic Asthma Pilot Study (TioNAAP)
Most children with asthma have concurrent atopy (allergic inflammation), which is associated with an improved response to ICS. However, the absence of an atopic phenotype is associated with a poorer ICS response, leaving…
- Trial name
- TioNAAP (NCT04990167)
- Testing
- Tiotropium Bromide
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Nemours Children's Clinic
Asthma
A Study of Depemokimab in Participants of 6 to 11 Years of Age
This study is aimed at assessing depemokimab as an add-on medicine for the treatment of asthma with type-2 inflammation in participants of 6 to 11 years of age.
- Trial name
- GLIDE (NCT07671001)
- Testing
- Depemokimab
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Asthma in Children
Virtual Care In Pediatric Asthma
The purpose of this study was to determine the impact of virtual care for children with asthma on the disease management and quality of life of children with asthma.
- Trial name
- NCT05500287
- Testing
- Virtual Care
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Ege University