Clinical trials: Asthma Childhood
Severe Asthma
Cohort Analysis of Clinical and Biological Severe Childhood Asthma
The purpose of this prospective study is: to identify by cluster analysis the main phenotypes of severe asthma and factors involved in the severity, to determine the clinical and functional outcomes, to identify the factors…
- Trial name
- COBRAPed (NCT02114034)
- Where
- France
- Volunteers
- 362 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Exercise Induced Laryngeal Obstruction, Asthma in Children
Prevalence of EILO Among Children With Asthma
The goal of this cross-sectional study is to investigate the prevalence of Exercise Induced Laryngeal Obstruction (EILO) in children with asthma.
- Conditions
- Exercise Induced Laryngeal Obstruction, Asthma in Children, Exercise-Induced Bronchospasm, Exercise-Induced Bronchoconstriction
- Trial name
- NCT06480084
- Testing
- Continuous Laryngoscopy during Exercise Test (CLE test)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Medisch Spectrum Twente
Asthma
Community Healthcare for Asthma Management and Prevention of Symptoms
The purpose of this study is to systematically investigate across health center study sites participating in this study the process of adopting, integrating, implementing, and diffusing a minimum set of evidence-based…
- Trial name
- CHAMPS (NCT02454192)
- Testing
- CHAMPS
- Where
- United States
- Volunteers
- 599 people
- Sponsor
- George Washington University
Asthma, Asthma in Children
Effectiveness of a Mobile Health Intervention in Improving the Technique of Inhaled Medications Among Children With Asthma
In this trial, the investigators aim to determine if a new mobile health intervention (BreatheSuite) can increase inhaler technique and adherence amongst participants aged 10-18.
- Trial name
- NCT03615248
- Testing
- BreatheSuite
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Memorial University of Newfoundland
Childhood Asthma, Childhood Anxiety
STRONGer Together: A Small Group Intervention for Children With Asthma and Anxiety/Depression
The proposed study is a one group pilot to assess the feasibility and acceptability of an 8-session intervention (STRONGer Together) for children between 8 - 12 years of age with asthma and anxiety/depressive symptoms.
- Conditions
- Childhood Asthma, Childhood Anxiety, Childhood Depression
- Trial name
- NCT04089085
- Testing
- STRONGer Together
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of North Carolina, Greensboro
Asthma in Children
Promoting Asthma Management Guidelines With Technology-Based Intervention and Care Coordination in Clinics and Schools
The overall goal of this research study is to evaluate a multi-level program called PRAGMATIC-S to improve the delivery of guideline-based asthma care through a unique partnership between clinical practices and schools.
- Trial name
- PRAGMATIC-S (NCT07224061)
- Testing
- PRAGMATIC-S
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Montefiore Medical Center
Asthma in Children
AmbuLatory Pediatric Asthma CAre
The ALPACA study has a prospective randomized control interventional design, including a follow-up period to evaluate follow-up effects. The study is divided into two phases of 3 months using eHealth and observational monitoring.
- Trial name
- NCT05517096
- Testing
- E-Health
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Asthma
Chronic-Dose Safety and Efficacy Study of Albuterol-HFA-BAI in Pediatric Asthmatics
This study is designed to evaluate the repeat-dose safety and effectiveness of a bronchodilator inhaler relative to placebo (inactive drug inhaler) in children aged 4-11 years with asthma.
- Trial name
- NCT00308685
- Testing
- Albuterol
- Where
- 14 sites in United States
- Volunteers
- 95 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Childhood Asthma
T Regulatory and Childhood Asthma
This is an epidemiologic study, examining environmental exposures and affect on immune development.
- Trial name
- NCT00204828
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Wisconsin, Madison
Asthma
Exercise Training in Asthma Children
The purpose of this study is to assess the effects of a physical training program with active video game in inflammatory markers, quality of life variables , clinical control and physical and functional respiratory assessment of…
- Trial name
- NCT01438294
- Testing
- Video game group, Aerobic exercise group
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Hospital Sirio-Libanes
Asthma, Dermatitis, Atopic
A Long-Term Examination of Asthma From Childhood Through Adolescence
Asthma is a common disease that is often diagnosed in childhood. In some teenagers, asthma symptoms disappear and treatment can be stopped; however, for some of these people, asthma symptoms return in adulthood.
- Conditions
- Asthma, Dermatitis, Atopic, Rhinitis, Urticaria
- Trial name
- NCT00541255
- Where
- United Kingdom
- Volunteers
- 1,313 people, healthy volunteers welcome
- Sponsor
- Isle of Wight NHS Trust
Asthma
Comparison of Nebulizers in ED in Pediatric Asthma Patients
The primary objective will be, in an open-label randomized trial, a comparison of emergency department (ED) length of stay (LOS) between children experiencing acute asthma treated with two different nebulizers.
- Trial name
- NCT01951378
- Testing
- Hudson RCI® nebulizer, NebuTech® HDN® nebulizer, Albuterol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seton Healthcare Family
Breastmilk Collection, Childhood Obesity
Breastmilk Composition and Microbial Profile in the Growth and Development of Healthy Term-born Infants
An increasing number of children are developing non-communicable diseases that carry immediate and long-term significant societal and economic impacts.
- Conditions
- Breastmilk Collection, Childhood Obesity, Childhood Asthma, Allergy
- Trial name
- NCT06970535
- Where
- 2 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Asthma, Acute Asthma
Single Dose Oral Dexamethasone Versus Multi-dose Prednisolone in the Treatment of Acute Exacerbations of Asthma in Children
A trial to investigate if a single dose of the oral corticosteroid, Dexamethasone is as effective in treating exacerbations of asthma in children as 3 days of treatment with another oral corticosteroid, Prednisolone
- Trial name
- NCT03698630
- Testing
- Prednisolone Sodium Phosphate, Dexamethasone
- Where
- Ireland
- Volunteers
- 250 people
- Sponsor
- University College Dublin
Immunotherapy, Allergy and Immunology
MAPS & ITEC Cohorts: 6-8 Years Follow-up
This study represents the follow-up, age 6-8 years, of children recruited at birth into two cohorts. The first cohort, the Mite Allergen Prevention Study (MAPS) was a double-blind, randomized controlled trial of the use of house…
- Conditions
- Immunotherapy, Allergy and Immunology, Asthma
- Trial name
- NCT03763630
- Testing
- House dust-mite SLIT, Normal saline
- Where
- 2 sites in United Kingdom
- Volunteers
- 263 people
- Sponsor
- University of Southampton
Pediatric Asthma, Critical Illness
Azithromycin for Critical Asthma - Pediatrics
The CR-AZI Study will assess the immunomodulatory effects of Azithromycin for pediatric Critical Asthma.
- Trial name
- CR-AZI Kids (NCT06223828)
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins All Children's Hospital
Asthma in Children
Montelukast and Loratadine in Children With Asthma
Randomized controlled trial in 80 children with mild to persistent moderate asthma, who were randomized to receive montelukast 5mg + loratadine 5mg vs.
- Trial name
- NCT03372473
- Testing
- Montelukast mixed with Loratadine, Montelukast
- Volunteers
- 80 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Asthma, Sleep
Sleep Quality in High School Students With Asthma - II
The overall goal of this project is to develop and to preliminarily validate a novel intervention to be delivered in the high school setting that integrates two evidence-based, school-based interventions for urban adolescents…
- Conditions
- Asthma, Sleep, Asthma in Children
- Trial name
- NCT03329066
- Testing
- MAST - Managing Asthma & Sleep in Teens, ASMA - Asthma Self-Management for Adol, Information & Referral Control Group
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Columbia University
Asthma
Progression of Airway Obstruction in Childhood Asthma
Distinct patterns of loss in pulmonary function were identified in children with mild to moderate asthma participating in a 10-year observation period during the NHLBI Childhood Asthma Management Program.
- Trial name
- NCT00873873
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Jewish Health
Asthma, Smoking Cessation
Sustaining Smoking Cessation in Smokers With Kids With Asthma
Parents of Asthmatics Quit Smoking (PAQS-2) is a randomized controlled trial of a smoking cessation intervention for parents who smoke.
- Trial name
- PAQS2 (NCT00862368)
- Testing
- PAM, PAM-Enhanced/Asthma Counseling Phone Calls, Follow-Up Phone Calls - Child Wellness Topic
- Where
- 5 sites in United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital