Clinical trials: Asthma Childhood
Pediatric Asthma
Developing a Childhood Asthma Risk Passive Digital Marker
Underdiagnosis and undertreatment is a major problem in childhood asthma management, especially in preschool-aged children. Current prognostic approaches using risk-score based tools have poor-to-modest accuracy, are impractical…
- Trial name
- NCT05826561
- Testing
- Childhood Asthma Passive Digital Marker
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Indiana University
Asthma in Children, Obesity, Childhood
Reducing Exercise-induced Bronchoconstriction in Children With Asthma and Obesity
Guidelines from the American Thoracic Society strongly recommend interval warm-up exercise before planned exercise to reduce exercise-induced bronchoconstriction severity.
- Conditions
- Asthma in Children, Obesity, Childhood, Exercise Induced Bronchospasm
- Trial name
- NCT03586544
- Testing
- Albuterol Sulfate, Interval Warm-up exercise
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Asthma
Comparison of Vibrating Mesh Nebulizer Versus Jet Nebulizer in the Pediatric Asthma Patient
The purpose of this study is to compare clinical outcomes related to the current practice of using a jet nebulizer (JN) with aerosol mask (AM) or mouthpiece (MP) versus a vibrating mesh nebulizer (VMN) with a valved-mask (VM) or…
- Trial name
- NCT02774941
- Testing
- Jet Nebulizer, Vibrating Mesh Nebulizer
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Childhood Asthma
Asthma Link: A Real World Application of School Supervised Asthma Therapy
The goal of this study is to assess the feasibility of a clinical trial to evaluate the impact and process of deploying school-supervised asthma therapy in a real-world setting for children with poorly controlled asthma (aged…
- Trial name
- NCT04942379
- Testing
- Asthma Link, Enhanced Usual Care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Massachusetts, Worcester
Asthma in Children
Personalized Treatment Algorithms for Difficult-to-treat Asthma
Asthma is a common, complex and costly chronic condition. Moreover, asthma is heterogeneous in terms of treatment response. This heterogeneity contributes to the difficulty in both studying and treating asthma.
- Trial name
- NCT04179461
- Testing
- Cholecalciferol, antihistamine, Azithromycin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Education, Medical
Repeated Versus Varied Simulation Scenarios to Teach Medical Students the Management of a Pediatric Asthma Exacerbation
Repeated exposure to simulated cases has been shown to improve performance, but repeating the same scenario may impair the ability of learners to transfer their knowledge and skills to slightly different situations.
- Trial name
- REVAR (NCT02754310)
- Testing
- Variation of scenarios, Repeated scenarios
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Ilumens
Asthma
RVA Breathes: A Richmond City Collaboration to Reduce Pediatric Asthma Disparities
The goal of this study is to evaluate a sustainable, community-engaged program to reduce asthma disparities among 5 to 11-year-old children in Richmond, Virginia.
- Trial name
- NCT03297645
- Testing
- School, Asthma education, Home environmental remediation
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Virginia Commonwealth University
Asthma
Albuterol HFA MDI in Pediatric Participants With Asthma
The primary objective of this study is to evaluate the chronic-dose and efficacy of Albuterol-HFA-MDI relative to placebo in pediatric asthmatics.
- Trial name
- NCT00577655
- Testing
- Albuterol, Proventil® HFA
- Where
- 13 sites in United States
- Volunteers
- 103 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma in Children
Effectiveness of Telemedicine Home Assessments for Identification and Reduction of Asthma Triggers
The study is about comparing asthma home assessments/interventions by telemedicine compared to providing education alone. Interactive Video (IAV) defines telemedicine.
- Trial name
- NCT04896502
- Testing
- Standard of Care Education, Interactive Video (IAV) Telemedicine
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Arkansas
Asthma, Depression
Defining and Treating Depression-related Asthma
Depression is seen more often in people with asthma, and may lead to increased development and severity of asthma. This study will investigate whether children with depression and asthma have less allergic disease and less…
- Conditions
- Asthma, Depression, Childhood Asthma
- Trial name
- NCT04617015
- Testing
- Ipratropium Bromide
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- State University of New York at Buffalo
Asthma in Children
Using Social Media to Decrease Healthcare Utilization for Pediatric Asthma
The purpose of this study is to evaluate if social media enhanced education (SME) will reduce total number of treatment days defined as summation of days of subsequent hospital admission, emergency room visits, and clinic visits…
- Trial name
- NCT05013788
- Testing
- Social Media Enhanced Education, Usual Asthma Education
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Asthma
Prevention of Asthma With Levocetirizine (36 Month Treatment) in Young Children Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and House Dust Mite and Having Completed the Previous EPAAC Trial (NCT00152464)
Prolongation of the EPAAC™ trial - NCT00152464 (The Early Prevention of Asthma in Atopic Children). 36 months study to evaluate the efficacy and safety of levocetirizine (LCTZ) in preventing the onset of asthma in young atopic…
- Trial name
- NCT00160563
- Testing
- LEVOCETIRIZINE
- Where
- 51 sites in Australia, Belgium and 8 more
- Volunteers
- 207 people
- Sponsor
- UCB Pharma
Pediatric, Asthma, Acute Exacerbation, Pediatric ICU
Use of High Frequency Chest Compression in Pediatric Status Asthmaticus
Asthma is a disease resulting in mucus hypersecretion and airways obstruction. This causes difficulty breathing. The High Frequency Chest Compressor (HFCC) is a device that has been shown to decrease respiratory complications in…
- Trial name
- NCT00552448
- Testing
- High Frequency Chest Compression VEST
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Texas Tech University Health Sciences Center
Asthma
Examining Changes in Nasal IL-1 During Acute Asthma Exacerbation in Adolescents
To study the change from baseline in IL-1β (interleukin 1 beta) concentrations in the nasal airway during acute asthma exacerbation, specifically to measure the degree of change and identify the timing of peak IL-1β…
- Trial name
- Attack Asthma (NCT04748055)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma
Comparison of Nebulizers in ED in Pediatric Asthma Patients
The primary objective will be, in an open-label randomized trial, a comparison of emergency department (ED) length of stay (LOS) between children experiencing acute asthma treated with two different nebulizers.
- Trial name
- NCT01951378
- Testing
- Hudson RCI® nebulizer, NebuTech® HDN® nebulizer, Albuterol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seton Healthcare Family
Asthma
Childhood Asthma Research and Education (CARE) Network Trial - Best Add-On Therapy Giving Effective Response (BADGER)
Asthma is a common, serious illness among children in the United States. While a low dose of inhaled corticosteroids (ICS) may effectively control symptoms, some children may require additional medications to maintain adequate…
- Trial name
- BADGER (NCT00395304)
- Testing
- fluticasone propionate + montelukast, fluticasone propionate, fluticasone propionate + salmeterol
- Where
- 5 sites in United States
- Volunteers
- 182 people
- Sponsor
- Milton S. Hershey Medical Center
Asthma
Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood Asthma (VDAART)
Vitamin D supplementation given to pregnant women will prevent asthma in their offspring and children.
- Trial name
- VDAART (NCT00920621)
- Testing
- Vitamin D 3 cholecalciferol, Vitamin D3
- Where
- 3 sites in United States
- Volunteers
- 876 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Asthma in Children, Humans
Interventions To Help Asthma Clinical Adherence
To conduct a pilot test to estimate the effect of a novel reminder system in improving daily asthma controller medication adherence rates in children with monolingual Spanish-speaking guardians who have limited English…
- Conditions
- Asthma in Children, Humans, Hispanic Americans, Child
- Trial name
- ITHACA (NCT02999789)
- Testing
- SmartInhaler with reminder function turned on, SmartInhaler
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Asthma, Asthma in Children
AQI and Childhood Asthma: an Intervention
This is a small pilot prospective intervention trial in children with asthma who will be randomized to receive either (A) Air Quality Index (AQI) education + an asthma action plan (control) or (B) AQI education + an asthma action…
- Trial name
- NCT04454125
- Testing
- AQI intervention, Routine care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Asthma
Environmental Intervention to Reduce Allergens in Urban Schools and Childhood Asthma
The investigators aim to pilot the role of school based intervention consisting of enhanced integrated pest management, classroom air purifiers and cleaning improves asthma morbidity.
- Trial name
- NCT01913795
- Testing
- integrated pest management, air purifier
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital