Clinical trials: Asthma Childhood
Asthma
Childhood Asthma Research and Education (CARE) Network Trial - Montelukast or Azithromycin for Reduction of Inhaled Corticosteroids in Childhood Asthma (MARS)
The MARS trial is a randomized, double-blind, parallel group study that compares the capacity of azithromycin or montelukast to placebo as effective adjunctive therapy that allows reduction of inhaled corticosteroids in children…
- Trial name
- MARS (NCT00471809)
- Testing
- Budesonide + Salmeterol + Azithromycin, Budesonide + Salmeterol + Montelukast
- Where
- 6 sites in United States
- Volunteers
- 210 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma, Allergy
Vitamin D, Steroids, and Asthma in African American Youth
Asthma has become considerably more prevalent and severe in the U.S. during the last 40 years, particularly affecting youth in urban areas, yet the reasons for this are not clear.
- Trial name
- AsthMaP2 (NCT01647399)
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Robert J. Freishtat
Asthma, Asthma in Children
Allergy, Asthma, and Atopic Eczema in Finland
The summary is available at --> https://www.finnatopy.fi/summary
- Conditions
- Asthma, Asthma in Children, Allergy, Rhinitis, Allergic
- Trial name
- FinnATOPY (NCT06330974)
- Testing
- No intervention, No Intervention: Observational Cohort
- Where
- Finland
- Volunteers
- 1,600,000 people
- Sponsor
- Tampere University
Childhood Asthma
Asthma Link: A Real World Application of School Supervised Asthma Therapy
The goal of this study is to assess the feasibility of a clinical trial to evaluate the impact and process of deploying school-supervised asthma therapy in a real-world setting for children with poorly controlled asthma (aged…
- Trial name
- NCT04942379
- Testing
- Asthma Link, Enhanced Usual Care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Massachusetts, Worcester
Asthma in Children, Electromyography
Continuous EMG Measurements in Children With Asthma During Sleep
The objective of this study is to investigate whether electromyography of the diaphragm during sleep in asthmatic children can be used to objectively monitor asthma control.
- Conditions
- Asthma in Children, Electromyography, Sleep-Disordered Breathing
- Trial name
- NCT05547477
- Volunteers
- 20 people
- Sponsor
- Medisch Spectrum Twente
Adolescent, Nursing Care
Mobile Health Application for Adolescents With Asthma
Mobile health applications (mHealth apps) are an opportunity offered by developing technology which in widely used among youths.
- Conditions
- Adolescent, Nursing Care, Asthma in Children, Self Efficacy
- Trial name
- NCT04691557
- Testing
- Mobile Health Application, Usual Care
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Akdeniz University
Asthma in Children
SBAT for Health Equity
The goal of this research trial is to: 1) Solidify a population health SBAT implementation strategy with our longstanding community collaborators, 2) Perform a district-wide hybrid type 3, stepped-wedge, cluster randomized trial…
- Trial name
- NCT05744869
- Testing
- SBAT Implementation, Usual Care
- Volunteers
- 300 people
- Sponsor
- University of Rochester
Asthma in Children
Comparasion of Efficacy of Nebulized With Intravenous Magnesium Sulphate in Children With Asthma
The purpose of study is to assess the effectiveness of nebulized magnesium sulphate in children presenting with acute asthma.Study perfoma consists of demographic variables,exclusion criteria and pediatric asthma score that…
- Trial name
- NCT04497766
- Testing
- Nebulized Magnesium sulfate, Intravenous magnesium sulphate
- Where
- Pakistan
- Volunteers
- 148 people
- Sponsor
- Saima Khatoon
Asthma in Children
Personalized Digital Health and Artificial Intelligence in Childhood Asthma
Asthma is a chronic inflammatory disease of the airways that causes recurrent episodes of wheezing, breathing difficulties and coughing.
- Trial name
- Asthmoscope (NCT04528342)
- Where
- 2 sites in Switzerland
- Volunteers
- 290 people
- Sponsor
- Isabelle Ruchonnet-Métrailler
Asthma in Children
Personalized Treatment Algorithms for Difficult-to-treat Asthma
Asthma is a common, complex and costly chronic condition. Moreover, asthma is heterogeneous in terms of treatment response. This heterogeneity contributes to the difficulty in both studying and treating asthma.
- Trial name
- NCT04179461
- Testing
- Cholecalciferol, antihistamine, Azithromycin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose…
- Conditions
- Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension
- Trial name
- POPS or POP02 (NCT04278404)
- Testing
- The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Asthma
Does Improving Insulation and Heating Improve Health?
The Housing, Heating and Health Study has enrolled 409 households with ineffective heaters, who have a child with asthma between 6 and 12 years.
- Trial name
- NCT00489762
- Testing
- Installation of an energy efficient heater
- Where
- New Zealand
- Volunteers
- 409 people
- Sponsor
- University of Otago
Pollution; Exposure, Environmental Exposure
The Impact of Synergies of Indoor Air Pollutants on Childhood Health and Wellbeing
To quantify health effects of synergizing chemical and biological pollutants in a targeted population setting, i.e., school-aged children. Indoor air pollutants will be monitored within the classrooms with high end sensors.
- Conditions
- Pollution; Exposure, Environmental Exposure, Childhood Asthma, Childhood
- Trial name
- SynAir-Child (NCT05105386)
- Testing
- SynAir-Child
- Volunteers
- 3,000 people
- Sponsor
- National and Kapodistrian University of Athens
Medication Adherence, Asthma in Children
The Tailored Adherence Incentives for Childhood Asthma Medications (TAICAM) Trial
Improving adherence to inhaled corticosteroids (ICS) medication in urban minority pediatric populations is a clinical and population health priority.
- Trial name
- NCT03907410
- Testing
- Nominal Financial Incentives, Daily Adherence Reminders/Adherence Performance Feedback
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Asthma in Children
Ex Vivo Pilot Study of the Impact of Nasal Breathing During the Administration of Inhaled Corticosteroids by Inhalation Chamber in Asthmatic Children Ages Between 1 and 4-year-old
The main purpose of this open randomized, ex-vivo comparative study, is to assess and to compare the inhalable dose of inhaled corticosteroid collected through a nasal filter and a mouth filter located in a partitioned face mask…
- Trial name
- MASQUE (NCT03364959)
- Testing
- Corticosteroids inhalation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Asthma in Children
The Duke-Reinvestment Partners Community Collaborative (DRC)- Healthy Homes
The goal of this open-label, single arm home intervention feasibility study is to improve quality of life for children ages 4-16 years with asthma.
- Trial name
- DRC (NCT05934370)
- Testing
- Home-Based Environmental Interventions (HEI)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Duke University
Asthma Acute, Asthma in Children
Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma
Acute asthma produces greatly increased work of breathing and increased oxygen requirement secondary to bronchial narrowing and airway obstruction by inflammatory secretions.
- Trial name
- NCT03296579
- Testing
- BiPAP, CPAP, Ipratropium
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Asthma
The Community United to Challenge Asthma
This study compares an asthma self-management intervention, delivered to the family and tailored to their needs and cultural beliefs, to standard asthma education in high-risk Puerto Rican children in elementary school.
- Trial name
- Project CURA (NCT01061424)
- Testing
- community health worker, mailed information
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Rush University Medical Center
Asthma
Examining Changes in Nasal IL-1 During Acute Asthma Exacerbation in Adolescents
To study the change from baseline in IL-1β (interleukin 1 beta) concentrations in the nasal airway during acute asthma exacerbation, specifically to measure the degree of change and identify the timing of peak IL-1β…
- Trial name
- Attack Asthma (NCT04748055)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma, Asthma Attack
Remote Patient Monitoring Solution for Chronic Respiratory Disease Management
Aim: To evaluate the use of AeviceMD Monitoring System (AeviceMD) asthma in reducing acute exacerbation. Methodology: Using a randomized controlled trial design, this project aims evaluate the effectiveness of AeviceMD in…
- Conditions
- Asthma, Asthma Attack, Asthma in Children, Asthma Acute
- Trial name
- NCT06377345
- Testing
- AeviceMD device, Standard care
- Where
- Singapore
- Volunteers
- 180 people
- Sponsor
- SingHealth Polyclinics