Clinical trials: Asthma Childhood
Asthma in Children
Sensitivity of Forced Oscillation Technique in Children With Asthma and Normal Spirometry
Exhibiting variable airway obstruction is a key factor in the diagnosis of asthma but too often it is undetected by spirometry. Study hypothesis: The forced oscillation technique (FOT) will show airway obstruction in asthmatic…
- Trial name
- NCT03755908
- Testing
- Forced oscillation technique (FOT)
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Rambam Health Care Campus
Asthma
Safety and Blood Level Study of Unit Dose Budesonide
The purpose of this study is to evaluate the tolerability and pharmacokinetics of three doses of MAP0010 (Unit Dose Budesonide) compared with Pulmicort Respules® (Budesonide) in healthy volunteers.
- Trial name
- UDB P101 (NCT00627679)
- Testing
- Budesonide Inhalation Suspension, MAP0010 low dose, MAP0010 intermediate dose
- Where
- Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Allergan
Asthma
Metabolomics in the Diagnosis and Treatment of Asthma in Children
The goal of this observational study is to learn about the metabolomic profile of blood and urine in children 12-17 years with asthma.
- Trial name
- NCT07280364
- Testing
- Standart medical treatment
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Asthma
A Study of Depemokimab in Participants of 6 to 11 Years of Age
This study is aimed at assessing depemokimab as an add-on medicine for the treatment of asthma with type-2 inflammation in participants of 6 to 11 years of age.
- Trial name
- GLIDE (NCT07671001)
- Testing
- Depemokimab
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Asthma in Children
Use of Air Purifiers to Improve Respiratory Health in Children
The goal of this pilot study is to investigate if installing an air purifier in the homes of children and young people with asthma improves their asthma outcomes.
- Trial name
- NCT05817357
- Testing
- Rensair Compact air purifier unit
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Liverpool
Asthma
A Pilot Study of Personalized Medicine for Pediatric Asthma
A pilot study to test the feasibility of a personalized asthma care intervention.
- Trial name
- NCT01681732
- Testing
- Personalized Care Plan, Control Standard Care
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Milton S. Hershey Medical Center
Childhood Asthma, Childhood Anxiety
STRONGer Together: A Small Group Intervention for Children With Asthma and Anxiety/Depression
The proposed study is a one group pilot to assess the feasibility and acceptability of an 8-session intervention (STRONGer Together) for children between 8 - 12 years of age with asthma and anxiety/depressive symptoms.
- Conditions
- Childhood Asthma, Childhood Anxiety, Childhood Depression
- Trial name
- NCT04089085
- Testing
- STRONGer Together
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of North Carolina, Greensboro
Wheezy Bronchitis, Asthmatic Bronchitis
Efficacy of Intermittent Tiotropium in Early Childhood Wheezing
This study evaluates the effect of intermittent tiotropium bromide and salbutamol as needed versus intermittent fluticasone propionate and salbutamol as needed, or solely, salbutamol as needed on episode-free days in infants and…
- Conditions
- Wheezy Bronchitis, Asthmatic Bronchitis, Wheezing, Obstruction Airway
- Trial name
- NCT03199976
- Testing
- Tiotropium Bromide, Fluticasone Propionate, Salbutamol
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital
Wheeze
Treating Wheezing in Children With Hypertonic Saline (TWICS)
Hypothesis: substitution of nebulized 3% NaCl (HS) for the standard normal saline (NS) used in bronchodilator therapy for acute viral wheezing in all children under age 6 years will provide superior symptom relief leading to…
- Trial name
- TWICS (NCT01868932)
- Testing
- hypertonic saline, saline
- Sponsor
- Dr. Michael Flavin
Asthma in Children
Virtual Care In Pediatric Asthma
The purpose of this study was to determine the impact of virtual care for children with asthma on the disease management and quality of life of children with asthma.
- Trial name
- NCT05500287
- Testing
- Virtual Care
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Ege University
Asthma
Efficacy of Ciclesonide Inhaled Once Daily Versus Other Corticosteroids Used for Treatment of Mild Asthma in Children (4 to 11 Years) (BY9010/CA-101)
The aim of this study is to compare the efficacy of ciclesonide with respect to reduction of the number of asthma exacerbations in children with mild persistent asthma.
- Trial name
- POPCICLE (NCT00163293)
- Testing
- Ciclesonide
- Where
- 7 sites in Canada, Hungary and 1 more
- Volunteers
- 240 people
- Sponsor
- AstraZeneca
Asthma in Children, Influenza Vaccine
Influenza Vaccine in Children With Asthma
The occurence of influenza can be a factor of imbalance of asthma. Asthma patients are recommended for annual influenza vaccination .
- Conditions
- Asthma in Children, Influenza Vaccine, Immunization Coverage
- Trial name
- VAGA (NCT04086628)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Environmental Exposure, Health Behavior
The Barts Charity Children's Environmental Health Clinic
The study will be based from a newly formed NHS service, the children's environmental health service. Participants will be children with a known chronic respiratory condition.
- Conditions
- Environmental Exposure, Health Behavior, Asthma in Children, Environmental Illness
- Trial name
- BCCEHC (NCT06447974)
- Testing
- Exposure mitigations
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Asthma in Children
Improving Asthma Referrals Following Emergency Department Evaluation
Asthma is the most common chronic condition among children and many children seek emergency department (ED) care. A key aspect of ED asthma management at the time of discharge is appropriate outpatient referral.
- Trial name
- NCT05072808
- Testing
- View PACCI-ED and referral recommendations
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Wayne State University
Asthma in Children
Chicago Asthma School-Directed Child-Centered Assessment and Dissemination of Evidence
Research has shown that adherence to evidence-based asthma guidelines leads to improved outcomes, yet critical gaps remain in the implementation of these guidelines, particularly among minority and low-income youth.
- Trial name
- CASCADE (NCT06320210)
- Testing
- Multicomponent program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Asthma in Children
Impact of Nurse-led Intervention on Asthma Control in Children
This randomized control trial design (RCT) study was conducted on children aged 6 -11 years
- Trial name
- NCT05855512
- Testing
- Nursing Educational Intervention
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Dow University of Health Sciences
Asthma
Chronic-Dose Safety and Efficacy Study of Albuterol-HFA-BAI in Pediatric Asthmatics
This study is designed to evaluate the repeat-dose safety and effectiveness of a bronchodilator inhaler relative to placebo (inactive drug inhaler) in children aged 4-11 years with asthma.
- Trial name
- NCT00308685
- Testing
- Albuterol
- Where
- 14 sites in United States
- Volunteers
- 95 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Childhood Asthma, Asthma Control
Pollution Intervention to Impact Kids Asthma Study
The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children.
- Conditions
- Childhood Asthma, Asthma Control, Asthma Exacerbation, Air Pollution, Risk Reduction Behaviors
- Trial name
- PIKAS (NCT07261423)
- Testing
- EPA-AQI, Commerical-AQI, Education and plan
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- University of Pittsburgh
Asthma
Coaching in Childhood Asthma
Asthma among low-income, minority children remains a prime example of health disparities that are resistant to change. Demonstrations of reductions in disproportionate hospitalizations in controlled trials are limited.
- Trial name
- Coach (NCT00910585)
- Testing
- Coaching, providing social support
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Washington University School of Medicine
Asthma in Children
Airway Microbiota Based Treatment of Asthma in Preschool Children
Airway microbiota pattern may related the preschool asthma exacerbation. This is a single-center, randomized-controlled trial, the study will compare the management of preschool wheeze determined by airway microbiota phenotype…
- Trial name
- AMBT (NCT04527016)
- Testing
- Microbiota and eosinophils based therapy, Clinical guidelines based therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Children's Hospital of Fudan University