Clinical trials: Asthmatics
Asthma, Lung Diseases, Obstructive
Early Risk Predictors For Chronic Pulmonary Disease
To continue to evaluate risk factors heretofore determined to be important predictors of chronic respiratory symptoms, diagnosis of asthma, and alterations in expected levels of lung function in children and adolescents in a new…
- Conditions
- Asthma, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00005281
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma
Feasibility of a Clinician Training Program to Improve Patient-provider Communication in the Presence of Health IT Systems in the Exam Room
The investigators propose to modify and expand the internationally-recognized evidence-based Physician Asthma Care Education (PACE) program to make it a suitable tool for training primary care clinicians on the effective use of…
- Trial name
- NCT02915068
- Testing
- EHR-Physician Asthma Care Education Program
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Michigan
Asthma
A Study to Measure Serum Periostin, Asthma-Related Biomarkers and Response to Prednisolone in Adult and Adolescent Patients With Severe Oral Corticosteroid-Dependent Asthma
This interventional, open study will evaluate clinical data in relation to biomarkers in patients 12 to 75 years of age with severe oral corticosteroid (OCS) - dependent asthma.
- Trial name
- NCT01948401
- Testing
- LABA, corticosteroids, prednisolone
- Where
- 11 sites in United Kingdom
- Volunteers
- 54 people
- Sponsor
- Hoffmann-La Roche
Allergy
Efficacy of SLITone in House Dust Mite Allergic Patients
This trial has been designed to evaluate the efficacy of specific immunotherapy with SLITone Dermatophagoides mix compared with placebo in subjects with house dust mite allergic asthma, based on asthma medication use during a…
- Trial name
- NCT00633919
- Testing
- SLITone(TM) Dermatophagoides mix, Salbutamol inhaler, Budesonide/formoterol inhaler
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- ALK-Abelló A/S
Atropine Bioequivalence
Sublingual Atropine Bioequivalence by Route of Administration (SABER)
A randomized, two-period, two-sequence, crossover study to assess the bioequivalence, bioavailability, and pharmacokinetics (PK) of a single dose of atropine administered sublingually (SL) or intramuscularly (IM) in healthy adult…
- Trial name
- SABER (NCT06366087)
- Testing
- Atropine Sulfate Ophthalmic Solution USP, 1%, Atropine Sulfate Injection, USP 8 mg/20 mL (0.4 mg/mL)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Biomedical Advanced Research and Development Authority
Asthma
Single Dose Bronchodilatory Study in Asthma
Study to evaluate the bronchodilator effects of Zyflo CR in patients with chronic stable asthma.
- Trial name
- NCT01805687
- Testing
- Zileuton extended release
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Cornerstone Therapeutics Inc.
Bronchial Asthma With eNO-levels Greater Than 30 ppB
Cell Distribution in Induced Sputum in Patients With Asthma
The aim of this case-control study is the comparison of the cell distribution in induced sputum in young adults with asthma and in healthy controls. The study consists of two visits.
- Trial name
- NCT01543516
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Asthma
Inhaler Adherence and Inhalation Technique Assessed by a Smart Spacer in Patients with Severe Asthma on Biologics
Severe refractory asthma affects about 3.5% of asthma patients, often necessitating biologic therapy in addition to standard treatment.
- Trial name
- OUTERSPACE-3 (NCT06360393)
- Testing
- Smart spacer
- Where
- 5 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- University Medical Center Groningen
Asthma
Study of TNFR:Fc (Enbrel) in the Treatment of Asthma
The proposed study is a phase II clinical trial of TNFR:Fc therapy in a segmental allergen bronchoprovocation model of atopic asthma.
- Trial name
- NCT00001893
- Testing
- TNFR:Fc
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Gestational Diabetes Mellitus in Pregnancy, Gestational Hypertension
No-worry Baby Project
The Huizhou mother-infant cohort was set up to investigate the effect of dietary factors and environmental exposures during pregnancy on health consequences of mothers and offsprings in Huizhou, China.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Gestational Hypertension, Thyroid Disease Pregnancy, Obesity
- Trial name
- NCT03922087
- Testing
- No intervention
- Where
- China
- Volunteers
- 5,216 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Asthma
Efficacy and Safety Study of GSK679586 in Patients With Severe Asthma
Treatment, Randomised, Double Blind, Parallel Assignment, Safety/efficacy Study
- Trial name
- NCT00843193
- Testing
- INTRAVENOUS GSK679586, FLUTICASONE PROPIONATE
- Where
- 35 sites in United States, France and 6 more
- Volunteers
- 198 people
- Sponsor
- GlaxoSmithKline
Asthma
Self-care, Remote Monitoring and Elearning for Children and Young People With Asthma
Asthma is a long-term condition in children, often managed by general practitioners (GPs) in primary care but some children with asthma need hospital treatment and care by experienced paediatricians and nurses.
- Trial name
- ASTHMAME (NCT05972226)
- Where
- United Kingdom
- Volunteers
- 96 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Asthma in Children, Asthma
Improving Quality of Life for Teenagers With Asthma
BACKGROUND: Asthma is a long-term lung condition affecting 1 in 11 children and young people in the UK. Many teenagers have well controlled asthma, but a significant number continue to experience regular symptoms and asthma…
- Trial name
- IMPAQT (NCT06851715)
- Testing
- Clinic consultation focused on asthma self-management
- Where
- 2 sites in United Kingdom
- Volunteers
- 98 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Asthma
A Randomized Trial Comparing Metered Dose Inhalers and Breath Actuated Nebulizers
This study is determines if metered dose inhalers are as effective as breath actuated nebulizers for the treatment of mild to moderate asthma exacerbations in pediatric patients presenting to the emergency department.
- Trial name
- NCT02777125
- Testing
- Metered Dose Inhaler, Breath Actuated Nebulizer
- Volunteers
- 980 people
- Sponsor
- Le Bonheur Children's Hospital
Asthma, Lung Diseases
Genetics of Asthma and Bronchial Hyperresponsiveness
To investigate the genetics of asthma by reexamining a carefully characterized population of patients with asthma, and by studying their families.
- Trial name
- NCT00005359
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma
PEEP as Rescue Therapy for Asthmatics With Elevated BMI
The purpose of this study is to test the effect of increasing lung volume with a simple hand-held device to both prevent, and also to relieve, airway constriction in people with asthma and a BMI ≥ 30 kg/m2.
- Trial name
- NCT02696980
- Testing
- Positive Expiratory Pressure
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Vermont
Asthma
The Potential Added Value of Impulse Oscillometry in Asthma Monitoring
The goal of this longitudinal observational study is to learn if impulse oscillometry (IOS) has an added value in asthma monitoring in adult asthma patients who are prescribed a change in asthma maintenance therapy.
- Trial name
- AM-IOS (NCT06425562)
- Testing
- Full lung function, Multiple breath nitrogen washout, Impulse oscillometry
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Asthma
Use of Biologics for Severe Asthma in Hong Kong
The landscape of biologics therapy used in Hong Kong is currently unknown. The purpose of this study is to conduct a retrospective analysis of the use of biologics treatment for severe asthma in Hong Kong.
- Trial name
- NCT06778746
- Testing
- no interventions
- Where
- Hong Kong
- Volunteers
- 360 people
- Sponsor
- Chinese University of Hong Kong
Asthma, Wheezing
Individualized Therapy For Asthma in Toddlers
The INFANT study will test whether, in preschool children 12-59 months of age with persistent asthma, the following Step 2 asthma therapies will provide similar degrees of asthma control: 1.
- Trial name
- INFANT (NCT01606306)
- Testing
- daily fluticasone propionate, Montelukast, as-needed fluticasone propionate
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- Milton S. Hershey Medical Center
Therapy, Oxygen Inhalation
Effect of Halotherapy in Children With Asthma
Introduction: Asthma is a chronic respiratory disease that can affect all age groups and is characterized by episodic and reversible wheezing, shortness of breath, chest tightness and cough attacks.
- Trial name
- NCT06250452
- Testing
- Halotherapy (Salt Therapy)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Igdir University