Clinical trials: Astigmatism
Myopia
Topography-Guided Customized PRK Versus Q-value Adjusted PRK in Correction of Myopia With or Without Astigmatism
This study will include patients who will undergo PRK in both eyes, for each patient each eye will be randomly allocated to one of 2 procedures: topography-guided ablation in one eye (group I) and Q-factor customized ablation in…
- Trial name
- NCT03291873
- Testing
- PRK
- Where
- 2 sites in Egypt
- Volunteers
- 104 people
- Sponsor
- Kasr El Aini Hospital
Corneal Astigmatism
Limbal Relaxing Incisions Versus Paired 4 mm Clear Corneal Incisions on Steep Meridian During Phacoemulsification
The goal of this is prospective, computer based randomized clinical trial is to compare the efficacy of reduction of the pre-existing corneal astigmatism at the time of cataract surgery in patients admitted in sohag university…
- Trial name
- LRI-CCI (NCT05593263)
- Testing
- surgical correction of astigmatism with cataract
- Volunteers
- 120 people
- Sponsor
- Sohag University
Myopia, Astigmatism
Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery
We are enrolling participants aged 22 and older to have LASIK surgery in both eyes. We will perform wavefront-guided LASIK in one eye and ray tracing-guided LASIK in the fellow eye of each participant.
- Trial name
- NCT07078799
- Testing
- LASIK
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia, Astigmatism
On-Eye Evaluation of Contact Lens Axis Location
The purpose of this study was to evaluate the axis location of toric contact lenses after 3 minutes of wear. During this 1-visit study, each participant wore 3 pairs of study lenses of various design iterations (2-87-1, 2-87-2…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT02100410
- Testing
- Delefilcon A toric contact lens T1, Delefilcon A toric contact lens T2, Delefilcon A toric contact lens T3
- Volunteers
- 50 people
- Sponsor
- Alcon Research
Astigmatism, High Myopia
Comparison Between TICL and ICL+AK for High Myopic Astigmatism
To compare the outcomes of a toric Implantable Collamer Lens (ICL) and a spherical Implantable Collamer Lens combined with astigmatic keratotomy (AK) in the correction of high myopic astigmatism.
- Trial name
- NCT03202485
- Testing
- Toric Implantable Collamer Lens, ICL + Astigmatic keratotomy
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Astigmatism
Toric Contact Lens Digital Performance and Comfort Study
This study seeks to quantify digital visual performance and subjective visual acceptance of toric contact lenses as compared to spherical lenses in low to moderate astigmatic patients.
- Trial name
- NCT04772560
- Testing
- Precision1 for Astigmatism, Precision1 Sphere
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kathryn Richdale
Primary Pterygium, Astigmatism
Preoperative and Postoperative Refractive and Topographic Evaluation in Patients With Primary Pterygium: Comparison of Two Surgical Techniques
This study evaluated changes in refractive status and corneal topography before and after surgical treatment of primary pterygium.
- Trial name
- RETOP (NCT07742995)
- Testing
- Conjunctival Autograft, Amniotic Membrane Transplantation
- Volunteers
- 78 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Corneal Astigmatism, Intraocular Pressure
How Astigmatism Influences Corneal Biomechanics and Intraocular Pressure
The aim of the study was to identify whether preoperative corneal astigmatism can influence corneal biomechanics and the assessment of intraocular pressure (IOP) following micro-incision phacoemulsification.
- Conditions
- Corneal Astigmatism, Intraocular Pressure, Cataract Senile
- Trial name
- NCT03162471
- Testing
- non-contact measurement of intraocular pressure
- Volunteers
- 39 people
- Sponsor
- Medical University of Lodz
Astigmatism
Surgical Correction of Astigmatism
Laser correction for myopia and astigmatism using an excimer laser has been performed with success for several years. During the last 2 years, a new method for correction of refractive errors has emerged.
- Trial name
- NCT01680354
- Testing
- ReLEx, LASIK
- Where
- Denmark
- Sponsor
- Aarhus University Hospital
Corneal Astigmatism
Treatment of Vision Disturbances Due to Corneal Irregularities by Trans-epithelial Optical Phototherapeutic Keratectomy (TE-oPTK)
This study sets out to evaluate the EpiMaster application software for use in predicting the refractive change induced by a trans-epithelial phototherapeutic keratectomy (TE-PTK) procedure in eyes with irregularly irregular…
- Trial name
- NCT03841253
- Testing
- Trans-epithelial PTK, Trans-epithelial PTK (retrospective data collection), EpiMaster Application Software
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- London Vision Clinic
Astigmatism
Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study was to compare the clinical performance of two monthly toric silicone hydrogel contact lenses in habitual wearers, when worn for 1-month each.
- Trial name
- NCT05933772
- Testing
- Lens A (comfilcon A toric lens), Lens B (lehfilcon A toric lens)
- Where
- 5 sites in United States, Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Myopia, Astigmatism
Clinical Evaluation of WaveLight Plus LASIK
This study is a single-site, single-arm, prospective, observational study of subject satisfaction, quality of vision, and quality of life after bilateral LASIK surgery. Subjects will be assessed up to 3 months post-operatively.
- Trial name
- NCT07127757
- Testing
- Wavelight Plus LASIK
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Laser Defined Vision
Myopia, Astigmatism
Clinical Validation of Biofinity Toric MTO (Made To Order) Lenses
The study hypothesis is there is no difference in the clinical performance between the test and control lenses, in particular in lens stability, toric mislocation, comfort ratings and anterior segment ocular health findings.
- Trial name
- NCT02185105
- Testing
- comfilcon A MTO, comfilcon A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Cataract, Astigmatism
Evaluation of the Accuracy & Safety of the LaserArcs Nomogram
Evaluation of the Accuracy and Safety of the LaserArcs Femtosecond Cataract Surgery Arcuate Incision Nomogram in Patients Undergoing Cataract Surgery and Astigmatism Reduction
- Trial name
- NCT05278442
- Testing
- LaserArc
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Research Insight LLC
Astigmatism High Both, Pseudophakia
Toric Trifocal IOL Treatment With High Astigmatism and Hyperopia vs SMILE Enhancement After Trifocal IOL Treatment
The aim of this study is to assess visual and refractive outcomes after Toric Trifocal lens implantation and visual outcomes after laser vision correction (LVC) - ReLex Smile to correct residual refraction after 6 months of Toric…
- Conditions
- Astigmatism High Both, Pseudophakia, Hyperopia
- Trial name
- NCT04468022
- Testing
- Toric Trifocal IOL
- Where
- Kosovo
- Volunteers
- 40 people
- Sponsor
- Eye Hospital Pristina Kosovo
Cataract, Astigmatism
Astigmatism Correction With Intrastromal Arcuate Incisions in Eyes Undergoing Cataract Surgery With Femtosecond Laser Using the Cassini Ambient With Iris Registration (ARCUATAS)
This is an observational, prospective follow-up post-marketing study of CE marked medical devices aimed at treating astigmatism in patients with cataracts.
- Trial name
- ARCUATAS (NCT05053620)
- Testing
- Calculation of the arcuate intrasomal incisions
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- OFTALVIST (Oftalmología Vistahermosa S.L)
Myopia, Myopic Astigmatism
A Clinical Trial Assessing the Safety and Effectiveness of Orthokeratology Lenses in Patients With Myopia and Myopic Astigmatism
This is a prospective, multi-centre, single-arm clinical trial to evaluate the effectiveness and safety of MCOK-01 lenses in patients with myopia and myopic astigmatism who need dioptric correction.
- Trial name
- SEMOA (NCT07047924)
- Testing
- MCOK-01
- Where
- 4 sites in Australia
- Volunteers
- 220 people
- Sponsor
- Menicon Co., Ltd.
Astigmatism
Limbal Astigmatic Keratotomy to Correct High Degrees of Astigmatism After Phacoemulsification
Compare manually performed Astigmatic Keratotomy to femtosecond laser astigmatic keratotomy to manage corneal astigmatism more than three diopters after phacoemulsification.
- Trial name
- NCT06179355
- Testing
- manual astigmatic keratotomy, femtosecond laser astigmatic keratotomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Corneal Astigmatism
Toric IOL vs Non-toric IOL With LRI for Corneal Astigmatism
The purpose of the study is to compare the astigmatism reducing effect of a toric intraocular lens (IOL) (model MX60T - Bausch \& Lomb) with that of limbal relaxing incisional surgery combined with a non toric IOL (model MX60 …
- Trial name
- NCT03633851
- Testing
- Toric intraocular MX60T lens, Standard MX60 plus corneal incisions
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ashford and St. Peter's Hospitals NHS Trust
Aphakia, Corneal Astigmatism
Clareon Toric Study (T2-T9)
The purpose of this post-market study is to describe the long-term safety and performance of Clareon Toric Intraocular Lenses (IOLs).
- Trial name
- NCT06285695
- Testing
- Clareon Toric IOL, Cataract surgery
- Where
- 6 sites in Canada
- Volunteers
- 129 people
- Sponsor
- Alcon Research