Clinical trials: Astigmatism,
Mixed Astigmatism
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Mixed Astigmatism
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of mixed astigmatism up to 6.0 D, when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00761826
- Testing
- MEL 80 Mixed Astigmatism Treatment
- Where
- 5 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Refractive Error
On-Eye Evaluation of Contact Lens Rotation Marks
The purpose of this study was to select the size of the molded rotation mark for a new toric contact lens by comparing the visibility of various molded rotation marks.
- Trial name
- NCT02055404
- Testing
- Delefilcon A spherical contact lens with molded marks, Etafilcon A toric contact lens
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Myopia; Astigmatism
Dispensing Evaluation of Investigational Contact Lenses
Non-randomized, single-masked, 2-visit, bilateral wear, single-arm dispensing study to evaluate the visual acuity, rotational performance, lens fit, stability and subjective characteristics of a senofilcon-based JJVCI…
- Trial name
- NCT02625220
- Testing
- Prototype toric lens senofilcon A
- Where
- 12 sites in United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hyperopia
Complete Easy Rub Comparative Efficacy Study
The aim of this trial is to assess Complete Easy Rub compared to a competitor multi-purpose solution in terms of lens cleanliness, subjective response and ocular response, when lenses are worn bilaterally on a daily wear basis…
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01019564
- Testing
- Complete Easy Rub Formula MPS, Aquify MPS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Astigmatism
Patient Perception of Visual Distortions
The purpose of this study is to evaluate visual distortions reported by pseudophakic patients.
- Trial name
- NCT02203747
- Testing
- Administration of patient self-assessment
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia, Hyperopia
APIOC Sphere and APIOC Astigmatism
Vision and comfort, both objective and subjective, will be assessed for single vision contact lens wearers for either the APIOC™ Sphere or the APIOC™ Astigmatism contact lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT04806802
- Testing
- APIOC Sphere and APIOC Astigmatism
- Where
- 6 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Astigmatism
Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses
This is a prospective, multi-center, subject-masked, bilateral, daily wear, two-month dispensing study
- Trial name
- NCT02921412
- Testing
- fanfilcon A
- Where
- 4 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Hyperopic Presbyopia
Prospective Investigation of SUPRACOR Visual Outcomes of Presbyopic Hyperopic Patients With and Without Astigmatism
This phase IV study is an open, prospective, single-center, single-surgeon bilateral eye study to investigate the bilateral uncorrected intermediate visual acuity of presbyopic hyperopic patients, who have been treated with…
- Trial name
- NCT01628146
- Testing
- SUPRACOR LASIK treatment
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Cataract, Lens Opacities
Feasibility Investigation of Biometry and Tomography Measurements in a Heterogeneous Patient Cohort
The planned clinical investigation will be conducted to acquire raw data for the development of the algorithm. The data acquisition is intended to obtain first impressions of the potential performance of the changed hardware and…
- Conditions
- Cataract, Lens Opacities, Artificial Lens Implant, Corneal Astigmatism
- Trial name
- BioBase (NCT05458661)
- Testing
- Clinical Prototype BioBase (SN 07 and SN 08)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Astigmatism
Orientation Characteristics of Daily Disposable Toric Contact Lenses
Brief summary: Approximately 30 soft toric contact lens adapted subjects will be enrolled in this feasibility, bilateral, randomized, double-masked (subject and investigator), repeated measures insertion study.
- Trial name
- NCT06069609
- Testing
- kalifilcon A Daily Disposable Toric, Acuvue Oasys 1-Day for Astigmatism
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
Post-approval Study of New Enrolment Patients Undergoing Bilateral Treatment With the VisuMax SMILE Procedure
The objective of the post-approval study (PAS) is to assess patient experience of visual symptoms 6 months after bilateral treatment with the VisuMax SMILE procedure as measured by a patient questionnaire.
- Trial name
- NCT05740293
- Testing
- VisuMax SMILE procedure for the reduction or elimination of myopia with astigmatism
- Where
- 7 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Astigmatism
Corneal Astigmatism Measurement Study
To assess which commercially available measurement device is most accurate in measuring low (< 1.0 D) degrees of corneal astigmatism.
- Trial name
- NCT00818532
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Astigmatism
Toric Eye Strain and Stability Study
The purpose of this study is to determine the benefits of fitting low astigmats with soft toric contact lenses versus spherical contact lenses with regard to visual comfort, eyestrain, fitting efficiency, and visual performance.
- Trial name
- NCT01857102
- Testing
- etafilcon A, etafilcon A for Astigmatism
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia, Myopia
Apioc Contact Lens Feasibility
This clinical trial will document the feasibility of the Apioc lens design by assessing which lens shape parameters yield successful on-eye-fit and movement of the Apioc contact lens design and evaluate the subjectively-reported…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03688672
- Testing
- Apioc Contact Lens Design
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Ocular Physiology
Evaluation of ACUVUE® OASYS 1-Day for Astigmatism Contact Lenses With Alternative Lidstock
This will be a single-visit, randomized, double-masked, bilateral wear, non-dispensing, 2-sequence × 2-period crossover study to evaluate subject reported ocular symptoms.
- Trial name
- NCT05713552
- Testing
- Acuvue Oasys 1 Day for Astigmatism with Legacy lidstock, Acuvue Oasys 1 Day for Astigmatism with Amcor laminated lidstock
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Quantification of the Visual Benefits of Soft Toric Contact Lenses Compared to Soft Spherical Contact Lenses
The aim of this work is to undertake a range of vision-related measures with soft toric contact lenses soft spherical contact lenses and spectacle lens correction across a range of levels of astigmatism.
- Trial name
- NCT04613882
- Testing
- Soft Toric Custom Made Contact lens, Soft Spherical Contact Lenses, Spectacle Correction
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract Extraction, Corneal Astigmatism
Assessment of Visual Performance in Patients With Low Levels of Astigmatism
To assess visual performance in patients with low levels (0.5-0.75 Diopters) of corneal astigmatism.
- Trial name
- NCT00842231
- Testing
- Visual performance measures
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Astigmatism, Myopia
Vision Stability and Preference for Soft Toric vs. Soft Spherical Contact Lenses
The principal hypothesis is to be tested in this work is that vision stability (the primary outcome measure) with a spherical contact lens correction vs. a toric contact lens correction will be the same.
- Trial name
- NCT04536571
- Testing
- Test Contact lens, Control Contact lens
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
A Clinical Evaluation of a Phakic Intraocular Lens
The objective of this study is to evaluate the clinical performance of the STAAR EVO+ Visian™ Implantable Collamer® Lens with Aspheric (EDOF) Optic as refractive elements to correct or reduce myopia or hyperopia with presbyopia…
- Conditions
- Myopia, Hyperopia, Astigmatism, Presbyopia
- Trial name
- NCT07291739
- Testing
- Implantable Collamer Lens (ICL)
- Where
- Philippines
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Staar Surgical Company
Myopia, Astigmatism
Clinical Study to Evaluate Effectiveness of Digital Refraction
Prospective, comparative, randomized, non-masked clinical study to compare the a digital refraction with LogMAR VA testing utilizing trial lenses, to standard manual refraction using a Phoropter, and LogMAR VA testing, in…
- Trial name
- NCT03502863
- Testing
- Digital refraction, Manual Refraction
- Where
- 3 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Visibly