Clinical trials: Astigmatism
Astigmatism
Evaluation Study on Corneal Lens for Vision Correction
The objective of this study is to evaluate the fitting and visual outcomes of Nexis Lens, made of silicone commonly used in the contact lens industry, on healthy eye with or without astigmatism.
- Trial name
- NCT02053688
- Testing
- Astigmatic Correction Lens (Nexis ACCL lenses), Toric Soft Contact Lenses
- Where
- 6 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- FORSIGHT Vision3
Astigmatism
Orientation Characteristics of Daily Disposable Toric Contact Lenses
Brief summary: Approximately 30 soft toric contact lens adapted subjects will be enrolled in this feasibility, bilateral, randomized, double-masked (subject and investigator), repeated measures insertion study.
- Trial name
- NCT06069609
- Testing
- kalifilcon A Daily Disposable Toric, Acuvue Oasys 1-Day for Astigmatism
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study is to compare the clinical performance of two different daily disposable, SiHy toric contact lens types, Lens A and Lens B, in existing soft lens wearers when worn for one week each.
- Trial name
- NCT04831515
- Testing
- Lens A, Lens B
- Where
- 4 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract, Presbyopia
Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas
The objective of this study is to evaluate the clinical outcomes of the IC-8 IOL implanted in patients with complex corneas after crystalline lens removal.
- Conditions
- Cataract, Presbyopia, Irregular Astigmatism
- Trial name
- NCT05574270
- Testing
- IC-8 Intraocular Lens (IOL)
- Where
- 2 sites in Philippines, Singapore
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Astigmatism
Clinical Performance of Toric Hydrogel Contact Lenses Following One Week of Daily Wear
The aim of this prospective study is to evaluate the clinical performance of filcon IV1 toric and ocufilcon D toric contact lenses after 1 week of wear in each pair.
- Trial name
- NCT02847169
- Testing
- filcon IV1 toric lens, ocufilcon D toric lens
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Ocular Physiology
Evaluation of ACUVUE® OASYS 1-Day for Astigmatism Contact Lenses With Alternative Lidstock
This will be a single-visit, randomized, double-masked, bilateral wear, non-dispensing, 2-sequence × 2-period crossover study to evaluate subject reported ocular symptoms.
- Trial name
- NCT05713552
- Testing
- Acuvue Oasys 1 Day for Astigmatism with Legacy lidstock, Acuvue Oasys 1 Day for Astigmatism with Amcor laminated lidstock
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss
The primary objective of this study is to evaluate the distance, intermediate and near visual performance of Clerio designed single vision and Clerio designed LIRIC modified bifocal lenses (+2.00D add) compared to commercially…
- Trial name
- NCT03653715
- Testing
- Clerio Vision LIRIC-modified Bifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Contact Lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clerio Vision, Inc.
Myopia, Astigmatism
Post-approval Study of New Enrolment Patients Undergoing Bilateral Treatment With the VisuMax SMILE Procedure
The objective of the post-approval study (PAS) is to assess patient experience of visual symptoms 6 months after bilateral treatment with the VisuMax SMILE procedure as measured by a patient questionnaire.
- Trial name
- NCT05740293
- Testing
- VisuMax SMILE procedure for the reduction or elimination of myopia with astigmatism
- Where
- 7 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Astigmatism
Quantification of the Visual Benefits of Soft Toric Contact Lenses Compared to Soft Spherical Contact Lenses
The aim of this work is to undertake a range of vision-related measures with soft toric contact lenses soft spherical contact lenses and spectacle lens correction across a range of levels of astigmatism.
- Trial name
- NCT04613882
- Testing
- Soft Toric Custom Made Contact lens, Soft Spherical Contact Lenses, Spectacle Correction
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Hypermetropia
Use of the VisuMax Femtosecond Laser Lenticule Removal Procedure for the Correction of Hyperopia
The correction of farsightedness using ReLEx SMILE for hyperopia is focus of this investigation. The objective is to evaluate the safety and effectiveness.
- Trial name
- V1601CI (NCT03431571)
- Testing
- ReLEx SMILE
- Where
- 8 sites in China, Czechia and 4 more
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Astigmatism
Patient Perception of Visual Distortions
The purpose of this study is to evaluate visual distortions reported by pseudophakic patients.
- Trial name
- NCT02203747
- Testing
- Administration of patient self-assessment
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia, Astigmatism
Z8 OCT-controlled 2D vs 3D LASIK
The aim of this study was to test the hypothesis that OCT-guided 110 µm targeted flaps will result in accurate, predictable, and precise thickness flaps, with low complication rates when performed and compared using both 2D and…
- Trial name
- NCT04426175
- Testing
- 2D and 3D cutting method using a low energy Femtosecond laser LDV Z8 for LASIK flap cutting
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Zentrumsehstarke Hamburg
Myopia, Hyperopia
Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
A new multi-purpose solution (MPS)was clinically evaluated against Opti-Free RepleniSH MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01024855
- Testing
- RevitaLens OcuTec MPS (Investigational MPS) and Opti-Free RepleniSH MPS (control)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Moderate to High Myopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of moderate to high myopia (nearsightedness), when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762541
- Testing
- MEL 80 Treatment of High Myopia
- Where
- 5 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Astigmatism
Prospective Evaluation of the Long-term Effectiveness of the Femtosecond Laser-assisted Arcuate Incisions
This clinical study is an open, controlled, prospective, single center, single-surgeon, post-market-clinical-follow-up study to evaluate the long-term (18 months) effectiveness of the femtolaser-assisted astigmatic keratotomy.
- Trial name
- NCT02164994
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Astigmatism
Toric Eye Strain and Stability Study
The purpose of this study is to determine the benefits of fitting low astigmats with soft toric contact lenses versus spherical contact lenses with regard to visual comfort, eyestrain, fitting efficiency, and visual performance.
- Trial name
- NCT01857102
- Testing
- etafilcon A, etafilcon A for Astigmatism
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of ACUVUE OASYS® 1-Day for Astigmatism Lenses Produced on a New Manufacturing Line
This is a bilateral, dispensing, randomized, controlled, double-masked, 2×2 cross-over study to evaluate the clinical performance of ACUVUE OASYS® 1-Day for Astigmatism contact lenses produced on a recently qualified…
- Trial name
- NCT04794270
- Testing
- ACUVUE OASYS® 1-Day for Astigmatism - TAM 24, ACUVUE OASYS® 1-Day for Astigmatism
- Where
- 5 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Astigmatism
Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser
The objective of this clinical trial is to evaluate the safety and effectiveness of the Carl Zeiss Meditec VisuMax™ Femtosecond Laser lenticule removal procedure for the reduction or elimination of myopia from ≥ -1.00 D to ≤…
- Trial name
- NCT02430428
- Testing
- Carl Zeiss Meditec VisuMax Femtosecond Laser
- Where
- 5 sites in United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Astigmatism
Kalifilcon A Toric Compared to Commercially Available Lenses
Approximately thirty contact lens adapted subjects will be enrolled in this feasibility, bilateral, randomized, double masked (subject and investigator masked), repeated measures insertion study.
- Trial name
- NCT06098937
- Testing
- Kalifilcon Toric Lens, Total1 for Astigmatism, Precision1 for Astigmatism
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Hyperopia
Complete Easy Rub Comparative Efficacy Study
The aim of this trial is to assess Complete Easy Rub compared to a competitor multi-purpose solution in terms of lens cleanliness, subjective response and ocular response, when lenses are worn bilaterally on a daily wear basis…
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01019564
- Testing
- Complete Easy Rub Formula MPS, Aquify MPS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abbott Medical Optics