Clinical trials: Astigmatism
Refractive Astigmatism
Feasibility of iFS™ for Intrastromal Arcuate Keratotomy (ISAK) Procedures
The results of this trial will demonstrate that ISAK performed with the iFS™ femtosecond laser is a safe procedure.
- Trial name
- NCT01210820
- Testing
- iFS™ Femtosecond Laser System
- Where
- Austria
- Volunteers
- 21 people
- Sponsor
- Abbott Medical Optics
Astigmatism
A Clinical Performance of Two Soft Toric Contact Lenses
The study objective was to gather short-term clinical performance data for two soft toric contact lenses.
- Trial name
- NCT05633082
- Testing
- Lens 1 (omafilcon B), Lens 2 (fanfilcon A)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- CooperVision, Inc.
Ametropia, Astigmatism
Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses
The purpose of this study is to assess the clinical performance of TOTAL30 for Astigmatism (T30fA) soft contact lenses with Biofinity Toric soft contact lenses.
- Trial name
- NCT06165627
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 67 people
- Sponsor
- Alcon Research
Cataract, Astigmatism
Post-Approval Study of the TECNIS® Toric Extended Cylinder Range Intraocular Lens (IOL)
This study is a prospective, multicenter, bilateral, non-randomized, open-label, clinical study conducted at up to 20 sites in the USA.
- Trial name
- NCT02649842
- Testing
- TECNIS Toric Models ZCT450, ZCT525 or ZCT600
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Astigmatism
Evaluation of Orientation and Visual Acuity of Four Toric Soft Contact Lenses When Head is Tilted at 90 Degrees
The purpose of this study is to determine the relative performance of a new toric soft contact lens against three toric contact lens currently available in market, specifically with orientation and visual acuity when head is…
- Trial name
- NCT00583908
- Testing
- senofilcon A, balafilcon A toric, lotrafilcon B toric
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism, Myopia
Comparative Clinical Evaluation of Soft Toric Lens Designs
This study is evaluating the initial fit of toric contact lenses.
- Trial name
- NCT01552876
- Testing
- etafilcon A, nelfilcon A, Filcon II 3
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Safety and Effectiveness of Wavefront-guided LASIK for the Correction of Mixed Astigmatism
To demonstrate that wavefront-guided LASIK with measurements from iDesign is safe and effective in the treatment of mixed astigmatism.
- Trial name
- NCT01675492
- Testing
- LASIK
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Astigmatism
Performance of Toric Silicone Hydrogel Contact Lenses Following One Month of Daily Wear
The aim of this prospective study is to evaluate the clinical performance of fanfilcon A toric and lotrafilcon B toric contact lenses after 1 month of wear in each pair.
- Trial name
- NCT03418064
- Testing
- Fanfilcon A toric lens, Lotrafilcon B toric lens
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- CooperVision, Inc.
Refractive Ametropia, Astigmatism
1-Week Dispensing Evaluation of REVIVE™ Toric Soft Contact Lenses
Experienced soft contact lens wearing subjects were enrolled in this 1-week, post-market, bilateral, repeated measures, dispensing study.
- Trial name
- NCT06053736
- Testing
- REVIVE Toric Soft Contact Lenses
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Refractive Errors, Astigmatism
Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens
The purpose of this clinical study is to assess the clinical performance of an investigational toric soft contact lens compared to a commercially available toric contact lens in a crossover dispense trial when worn in a daily…
- Trial name
- NCT05211739
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Astigmatism
Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process
This is a prospective, multi-site, dispensing, randomized, controlled, double-masked, bilateral wear, 2x2 crossover study to evaluate the safety and effectiveness of the test lens.
- Trial name
- NCT06967129
- Testing
- Investigational daily disposable, soft, toric lenses manufactured on 4th Generation Technology (4GT) lines with extended mini-stack hydration using propylene glycol (PG) as the hydration solvent., ACUVUE® Oasys 1-Day for Astigmatism (AO1DfA) soft contact lenses manufactured on 3rd Generation Technology (3GT) legacy lines using isopropyl alcohol (IPA) as the hydration solvent.
- Where
- 20 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Comparison of Comfilcon A Toric Contact Lenses and Samfilcon A Toric Contact Lenses
The objective of this study is to evaluate the subjective acceptance of comfilcon A toric contact lens, compared to samfilcon A toric lens.
- Trial name
- NCT03519932
- Testing
- comfilcon A toric lens, samfilcon A toric lens
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- CooperVision, Inc.
Astigmatism
A Clinical Comparison of 2 Multifocal Toric XR (Extended Range) Contact Lenses
This study aims to compare the clinical performance and subjective acceptance of the comfilcon A and the omafilcon B soft contact lenses.
- Trial name
- NCT03006458
- Testing
- comfilcon A, omafilcon B
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Astigmatism
Clinical Comparison of Two Silicone Hydrogel Toric Lenses in the US
The purpose of this trial is to compare the performance of two different contact lenses for contact lens wearers with astigmatism.
- Trial name
- NCT01007812
- Testing
- Lotrafilcon B contact lens, Comfilcon A contact lens
- Volunteers
- 50 people
- Sponsor
- CIBA VISION
Cataract, Corneal Astigmatism
Post-Approval Study of the TECNIS SYMFONY® Toric Lenses
This study is a prospective, multicenter, bilateral, non-randomized, open-label, comparative, 6-month clinical study conducted at up to 50 sites in the USA.
- Trial name
- ANCORA (NCT03791619)
- Testing
- Higher Cylinder Toric IOL, Lower Cylinder Toric IOL
- Where
- 23 sites in United States
- Volunteers
- 475 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Astigmatism
Bilateral Dispensing Clinical Trial of Stenfilcon A Against Etafilcon A for Astigmatism
Bilateral dispensing clinical trial of stenfilcon A against etafilcon A for astigmatism.
- Trial name
- NCT02410824
- Testing
- stenfilcon A toric lens, etafilcon A toric lens
- Where
- 2 sites in United States, Canada
- Volunteers
- 52 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Ametropia
Clinical Performance of Two Daily Disposable Toric Soft Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1™ for Astigmatism (P1fA) contact lenses with 1-DAY ACUVUE MOIST® for ASTIGMATISM (AMfA) contact lenses.
- Conditions
- Refractive Errors, Ametropia, Astigmatism
- Trial name
- NCT04908488
- Testing
- Verofilcon A toric contact lenses, Etafilcon A toric contact lenses
- Where
- 8 sites in United States
- Volunteers
- 115 people
- Sponsor
- Alcon Research
Astigmatism, Myopia
Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism
The purpose of this trial is to compare the performance of two contact lenses for contact lens wearers with astigmatism.
- Trial name
- NCT01207466
- Testing
- Nelfilcon A investigational contact lens, Nelfilcon A commercial contact lens
- Volunteers
- 95 people
- Sponsor
- CIBA VISION
Cataract
Femtosecond Laser-assisted Arcuate Incisions Versus Manual Arcuate Incisions Outcomes
This study is designed to compare the effectiveness of LenSx laser arcuate relaxing incisions vs. manual (blade) arcuate relaxing incisions in patients with low, but significant, levels of astigmatism.
- Trial name
- NCT04126174
- Testing
- femtosecond laser system arcuate corneal incision, Manual LRI
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Gainesville Eye Associates
Aphakia, Presbyopia
Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs
This is a prospective, multicenter, post-approval active surveillance study. The purpose of this study is to report the rate of post-surgical intraocular inflammation (based upon a specified case definition) reported within a…
- Conditions
- Aphakia, Presbyopia, Astigmatism
- Trial name
- NCT03733730
- Testing
- ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL
- Where
- 38 sites in United States, Puerto Rico
- Volunteers
- 2,449 people
- Sponsor
- Alcon Research