Clinical trials: Astigmatism
Astigmatism
The Clinical Study of Silicone Hydrogel Daily Disposable Stenfilcon A Toric Lens
The aim of this study is to evaluate the clinical performance of stenfilcon A toric lenses compared with etafilcon A toric lenses for astigmatism.
- Trial name
- NCT02801006
- Testing
- stenfilcon A, etafilcon A
- Where
- 2 sites in Japan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Errors, Myopia
Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
The goal of this observational study is to test whether surgeries for lenses designed to be implanted in the eye to correct refractive error can be done without the need for using viscoelastic substances that are used routinely…
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism, Hypermetropia
- Trial name
- NCT06371079
- Testing
- phakic intraocular lens implantation traditional, phakic intraocular lens implantation reduced OVD
- Where
- Iraq
- Volunteers
- 448 people
- Sponsor
- Loay Abdulmutalib Almusawi
Cataract, Corneal Astigmatism
Clinical Investigation of the Safety and Effectiveness of an Investigational Model of the TECNIS® Intraocular Lens
This study will be a prospective, multicenter, bilateral, comparative, three-way masked (Sponsor, subject and evaluator), randomized clinical investigation conducted at up to 15 sites.
- Trial name
- BRAVO (NCT03949335)
- Testing
- IOL Model ZFR00V, IOL Model ZCB00
- Where
- 15 sites in United States
- Volunteers
- 272 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Cataract
Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism
The purpose is to evaluate the Calhoun Vision Light Adjustable Lens (LAL) and Light Delivery Device (LDD) for reducing astigmatism and improving uncorrected vision after implantation.
- Trial name
- NCT01496066
- Testing
- LAL (Light Adjustable Lens) and Light Deliver Device (LDD), Monofocal control IOL
- Where
- 17 sites in United States
- Volunteers
- 600 people
- Sponsor
- Calhoun Vision, Inc.
Myopia, Astigmatism
1-Week Dispensing Evaluation of Kalifilcon A Toric Contact Lenses Compared to Ultra for Astigmatism
This single-site, randomized, double-masked (participant and investigator), 2-way crossover, repeated-measures dispensing study evaluated the visual performance of kalifilcon A daily disposable toric (LD213001) contact lenses…
- Trial name
- NCT05320042
- Testing
- kalifilcon A daily disposable toric contact lenses, Ultra for Astigmatism (samfilcon A) contact lenses
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
Clinical Comparison of Two Daily Disposable Toric Lenses
The purpose of this trial was to compare the performance of two contact lenses commercially available for people with astigmatism.
- Trial name
- NCT01362894
- Testing
- nelfilcon A contact lens, etafilcon A contact lens
- Volunteers
- 240 people
- Sponsor
- CIBA VISION
Cataract, Corneal Astigmatism
Evaluation of the Rotational Stability of the Tecnis Toric II IOL
This is a prospective, multicenter, single-arm, open-label clinical study of the commercially available TECNIS Toric II IOL. The study will be conducted in up to 192 subjects needing unilateral or bilateral cataract surgery in up…
- Trial name
- STEELE (NCT04327518)
- Testing
- TECNIS® Toric II
- Where
- 7 sites in United States
- Volunteers
- 125 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia, Astigmatism
Comparison of Topography Guided LASIK With WaveLight® EX500 to SMILE With Zeiss VisuMax
The purpose of this study is to compare Topography Guided Laser In Situ Keratomileusis (LASIK) corneal surgery to Small Incision Lenticule Extraction (SMILE) corneal surgery for the treatment of myopia with astigmatism.
- Trial name
- NCT02987660
- Testing
- Topography Guided LASIK, Small Incision Lenticular Extraction, WaveLight EX500 Excimer Laser System
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Alcon, a Novartis Company
Aphakia, Corneal Astigmatism
Evaluation of the Safety and Performance of the HARMONI® Toric Lens
The purpose of this study was to evaluate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic (HMTIOL) in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Aphakia, Corneal Astigmatism, Cataract
- Trial name
- NCT03050697
- Testing
- HARMONI® Modular Toric Intraocular Lens, Cataract extraction with intraocular lens (IOL) implantation
- Where
- New Zealand
- Volunteers
- 16 people
- Sponsor
- ClarVista Medical
Myopia, Astigmatism
Prospective Study of Lens Performance of a Monthly Replacement Lens at Two Weeks and Four Weeks
The purpose of this study is to compare the overall performance of a monthly replacement contact lens when worn for one month and when worn for two weeks.
- Conditions
- Myopia, Astigmatism, Presbyopia
- Trial name
- NCT01293240
- Testing
- lotrafilcon B contact lens
- Volunteers
- 117 people
- Sponsor
- CIBA VISION
Myopia, Astigmatism
New Treatment Algorithm to Reduce Spherical Aberration After LASIK Correction for Myopia
The purpose of this clinical trial is to demonstrate that treatments generated by an investigational algorithm reduces spherical aberration compared to currently available iDesign treatments.
- Trial name
- NCT01988415
- Testing
- VSS-Rx1 OPM vs Commercial iDesign Treatment
- Where
- Colombia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Astigmatism
Bilateral Dispensing Study of MyDay Toric, 1-day Acuvue Moist for Astigmatism, and Dailies Aquacomfort Plus Toric Lenses
Bilateral dispensing study of MyDay Toric, 1-day Acuvue Moist for Astigmatism, and Dailies Aquacomfort Plus Toric lenses
- Trial name
- NCT03134248
- Testing
- Dailies Aquacomfort Plus Toric, 1-Day Acuvue Moist for Astigmatism, MyDay Toric
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Astigmatism
Evaluation of Two Toric Soft Contact Lenses After Two Weeks of Wear
The purpose of this study is to determine the relative performance of a new toric soft contact lens against a toric contact lens currently available in market, specifically with regards to the comfort and vision after two weeks…
- Trial name
- NCT00584220
- Testing
- senofilcon A toric, alphafilcon A toric
- Volunteers
- 96 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract, Corneal Astigmatism
ClarVista HARMONI Toric Trial With Intraoperative Exchange
The purpose of this study was to demonstrate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Cataract, Corneal Astigmatism, Aphakia
- Trial name
- NCT03054649
- Testing
- HARMONI® Modular Intraocular Lens System, Intraoperative optic exchange
- Where
- 2 sites in Mexico, Philippines
- Volunteers
- 44 people
- Sponsor
- ClarVista Medical
Astigmatism
Toric Contact Lens Performance Study
This study seeks to quantify digital visual performance and subjective visual acceptance of toric contact lenses as compared to spherical lenses in low to moderate astigmatic patients.
- Trial name
- NCT03546647
- Testing
- Dailies Aqua Comfort Plus Toric, Dailies Aqua Comfort Plus Sphere
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Houston
Astigmatism, Myopia
Vision Stability and Preference for Soft Toric vs. Soft Spherical Contact Lenses
The principal hypothesis is to be tested in this work is that vision stability (the primary outcome measure) with a spherical contact lens correction vs. a toric contact lens correction will be the same.
- Trial name
- NCT04536571
- Testing
- Test Contact lens, Control Contact lens
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error, Astigmatism
Visual Performance Investigation of Two Toric Soft Contact Lenses
The purpose of this study is to compare the amount of coma as measured by aberrometry induced by two silicone hydrogel toric lenses in astigmatic participants.
- Conditions
- Refractive Error, Astigmatism, Myopia, Hyperopia
- Trial name
- CARDINAL (NCT01858701)
- Testing
- Lotrafilcon B toric contact lens, Comfilcon A toric contact lens
- Volunteers
- 49 people
- Sponsor
- Alcon Research
Astigmatism
A Bilateral Dispensing Clinical Trial of an Sapphire Lens Against Senofilcon A Toric for Astigmatism Lens
This study was conducted to evaluate the clinical performance of an investigational silicone-hydrogel lens against Senofilcon A toric lens. The study results were not used for design validation of the investigational product.
- Trial name
- NCT02555098
- Testing
- Sapphire contact lenses, senofilcon A contact lenses
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- CooperVision, Inc.
Cataract Extraction, Corneal Astigmatism
Assessment of Visual Performance in Patients With Low Levels of Astigmatism
To assess visual performance in patients with low levels (0.5-0.75 Diopters) of corneal astigmatism.
- Trial name
- NCT00842231
- Testing
- Visual performance measures
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research