Clinical trials: Asynchrony, Patient-Ventilator
Patient Ventilator Interactions
Analysis and Evaluation of Asynchronies Between NIV Patients and Their Prisma VENT or LUISA Ventilator
This study aims to analyze the types, rates, and patterns of disturbances between the breathing of patients receiving non-invasive ventilation and their ventilator (patient-ventilator asynchronies, PVA) during routine therapy…
- Trial name
- NCT07768748
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Löwenstein Medical Technology GmbH & Co. KG
Respiratory Failure
Patient-Ventilator Dyssynchrony: How is the Effect of Management?
Although patient-ventilator asynchrony is a frequent phenomenon, its course following management is unknown. As the aid of a data recording system, we try to observe the consequence of patient-ventilator asynchrony following…
- Trial name
- NCT00683072
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
ARDS (Acute Respiratory Distress Syndrome), Respiratory Failure
Development and Prospective Validation of the AutoEIT Foundation Model for ARDS
Acute Respiratory Distress Syndrome (ARDS) is a highly heterogeneous condition, making precision mechanical ventilation challenging.
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), Respiratory Failure, Mechanical Ventilation, Ventilator-induced Lung Injury (VILI)
- Trial name
- NCT07898319
- Testing
- AutoEIT Model Training, AutoEIT Blinded Validation
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Ruijin Hospital
Respiratory Insufficiency
Respiratory Mechanics and Patient-ventilator Asynchrony Index in Patients With Invasive Mechanical Ventilation
The objective of the study is to estimate the incidence of asynchrony and to assess its relationship with respiratory mechanics. This will be a prospective cohort study, including patients under invasive mechanical ventilation.
- Trial name
- EpiSync (NCT02687802)
- Testing
- mechanical ventilation
- Where
- Brazil
- Volunteers
- 103 people
- Sponsor
- University of Sao Paulo General Hospital
Respiratory Failure, Mechanical Ventilation Complication
Patient-ventilator Asynchrony During Mechanical Non-Invasive Assisted-ventilation in Pediatric Patients (NavPed-NI)
The purpose of this study is to document the prevalence and type of asynchronies incidence during non-invasive mechanical ventilation in pediatric patients breathing under pressure support.
- Trial name
- NavPed-NI (NCT01238757)
- Testing
- Non-invasive Ventilation under Pressure Support, Non-Invasive ventilation under NAVA
- Where
- Switzerland
- Volunteers
- 7 people
- Sponsor
- University Hospital, Geneva
Non-Invasive Positive-Pressure Ventilation
Impact of Neurally Adjusted Ventilator Assist (NAVA) Mode on Patient Ventilator Asynchrony Using Helmet
Non invasive ventilation has been proposed to reduce the incidence of ventilatory dysfunction following abdominal aortic surgery.
- Trial name
- NAVAHELMET (NCT01161875)
- Testing
- Neurally Adjusted Ventilatory Assistance
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Pierre and Marie Curie University
Mechanical Ventilation Complication
Automated Detection of Patient Ventilator Asynchrony Using Pes Signal
Rationale: Patient-ventilator asynchrony (PVA) in mechanical ventilation is associated with adverse patient outcome such as a prolonged stay in the ICU and even mortality.
- Trial name
- NCT06186557
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
ARDS, Human
EIT in Patient Ventilator Asynchrony
Patient-ventilator asynchrony is an important clinical issue in mechanically ventilated patients. For patients with moderate to severe acute respiratory distress syndrome (ARDS), various types of patient ventilator asynchrony may…
- Trial name
- NCT04442815
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Cheng-Kung University Hospital
COP, Non-invasive Ventilation
Patient-ventilator Asychrony During Non-invasive Ventilation When COPD Patients Doing Exercise
Pulmonary rehabilitation programmes including aerobic exercise training have strong evidence of effectiveness in improving exercise capacity, dyspnoea and HRQL in patients with COPD.
- Conditions
- COP, Non-invasive Ventilation, Pulmonary Rehabilitation
- Trial name
- NCT04054622
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Guangzhou Medical University
Critical Illness
The Impact of Higher Positive End Expiratory Pressure on Patient-Ventilator Asynchrony
Patient-ventilator asynchrony is known to frequently occur during lung protective ventilation in patients with ARDS. Previous clinical studies showed that patient-ventilator asynchrony was associated with worse outcome in ICU.
- Trial name
- NCT04951960
- Testing
- Higher PEEP setting, Lower PEEP setting
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Osaka University
Acute Lung Injury
Assessment of Patient-ventilator Asynchrony by Electric Impedance Tomography
Patient-ventilator asynchrony (PVA) has deleterious effects on the lungs. PVA can lead to acute lung injury and worsening hypoxemia through biotrauma.
- Trial name
- PAVELA (NCT06290310)
- Testing
- EIT, patient-ventilator asynchrony assessment
- Where
- Hungary
- Volunteers
- 10 people
- Sponsor
- Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged
Weaning Period
Impact of Neurally Adjusted Ventilator Assist (NAVA) Mode on Patient Ventilator Asynchrony Using Non-invasive Ventilation (NAVA-NIV)
Non-invasive ventilation (NIV) has been proposed to reduce the incidence of ventilatory dysfunction following mechanical ventilation weaning.
- Trial name
- NAVA-NIV (NCT01280760)
- Testing
- Device: Neurally Adjusted Ventilatory Assistance
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Pierre and Marie Curie University
Automatic Adjustmen of Inspiratory Triger and Cycling-off
IntelliCycleTM 2.0 Improved Patient-ventilator Asynchrony During PSV
Pressure Support Ventilation use Expiratory triggering sensitivity (Esense) to transfer inspiration to expiration, the value of Esense is fixed.
- Trial name
- NCT04091269
- Testing
- automatic adjustmen of inspiratory triger and cycling-off based on waveform and PSV with fixed Esence
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Southeast University, China
Ventilator Associated Events, Asynchrony, Patient-Ventilator
Synchrony-Optimized Non-Invasive Ventilation Education Program and ICU Patients
The aim of this clinical trial is to find out whether a synchrony-optimized education program for non-invasive ventilation (NIV) can help ICU patients use their ventilator more effectively and improve their comfort, symptoms, and…
- Conditions
- Ventilator Associated Events, Asynchrony, Patient-Ventilator, Intensive Care (ICU), Noninvasive Ventilation
- Trial name
- NCT07291622
- Testing
- SYNC-NIV
- Volunteers
- 92 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Acute Respiratory Failure, Pediatric Respiratory Distress Syndrome
Closed-loop Synchronization Versus Conventional Synchronization
A prior research indicated that asynchrony between the patient and ventilator occurred in 33 percent of 19,175 breaths, and was seen in every patient.
- Trial name
- CHESTSIPP (NCT05731024)
- Testing
- close-loop synchronization controller with SPONT mode, Conventional synchronization settings with SPONT mode
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Brain Injuries, Mechanical Ventilation
Patient-ventilator Asynchrony in Patients With Brain Injury
Mechanical ventilation is an important support strategy for critically ill patients. It could improve gas exchange, reduce the work of breathing, and improve patient comfort.
- Trial name
- NCT03212482
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jian-Xin Zhou
Respiratory Effort, Respiratory Distress Syndrome
The Association Between Respiratory Effort Parameters During the First 48 Hours With Clinical Outcomes in Mechanically Ventilated Patients: A Prospective Observational Study.
Over-assisted mechanical ventilation (MV) is linked to respiratory muscle disuse atrophy, while under-assisted MV can lead to patient self-inflicted lung injury (P-SILI) or respiratory muscle injuries.
- Conditions
- Respiratory Effort, Respiratory Distress Syndrome, Lung Mechanics
- Trial name
- EFFORT-1 (NCT06433076)
- Where
- Thailand
- Volunteers
- 163 people
- Sponsor
- Ramathibodi Hospital
Acute Respiratory Failure, Mechanical Ventilation Complication
New Setting of Neurally Adjusted Ventilatory Assist During Mask Noninvasive Ventilation
Non invasive ventilation (NIV) is generally delivered by pneumatically triggered and cycled-off Pressure Support (PSP) through a facial mask.
- Trial name
- NCT03041402
- Testing
- PSP, NAVA, PSN
- Volunteers
- 14 people
- Sponsor
- Southeast University, China
Respiratory Insufficiency
A Diaphragmatic Electrical Activity Based Optimization Strategy During Pressure Support Ventilation
Pressure support (PS) is a commonly used mode of ventilation which is triggered based upon the patient's own inspiratory efforts. For the most part, pressure support is well tolerated by patients.
- Trial name
- NCT02067403
- Testing
- Pressure-support Eadi optimization
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Unity Health Toronto
Patient-Ventilator Asynchrony, Mechanical Ventilation Complication
Nurse Education to Reduce Patient-Ventilator Asynchrony in the PICU
A prospective cluster-randomized quality improvement trial was conducted to evaluate whether a structured nurse education program on ventilator waveform interpretation and alarm management reduces patient-ventilator asynchrony in…
- Conditions
- Patient-Ventilator Asynchrony, Mechanical Ventilation Complication, Nurse Education
- Trial name
- NCT07273487
- Testing
- Nurse Education on Ventilator Waveform and Alarm Management
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Dr. Behcet Uz Children's Hospital