Clinical trials: Asystole
Heart Failure, Excessive Amount of Blood / Fluid Transfusion
Anesthesia for Catheter Aortic Valve ImplantATIOn Registry
In modern cardiac surgery and cardiology Transcatheter Aortic Valve Implantation (TAVI) is an emerging procedure for high-risk patients that are assumed to be otherwise inoperable.
- Conditions
- Heart Failure, Excessive Amount of Blood / Fluid Transfusion, Intraoperative Cardiac Arrest During Cardiac Surgery, Critical Incident
- Trial name
- AVIATOR (NCT01390675)
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Cardiac Arrest, Simulation of Physical Illness
CPR Surface Choice on Chest Compression Quality
The objective of our randomized simulation study on mannequins with a population of Basic Life Support students is to compare the quality of chest compressions, taking depth as the main variable, in two simulated scenarios of…
- Trial name
- NCT06406101
- Testing
- Floor, Bed
- Where
- Spain
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Trauma, Cardiac Arrest
Airway Management Study in Physician Manned Helicopter Emergency Medical Services
An international airway management expert group has recently developed an Utstein-style template for uniform reporting of data from prehospital advanced airway management.
- Conditions
- Trauma, Cardiac Arrest, Emergencies
- Trial name
- AIRPORT (NCT01502111)
- Where
- Norway
- Volunteers
- 2,333 people
- Sponsor
- Norwegian Air Ambulance Foundation
Out-of-Hospital Cardiac Arrest
Arizona Prehospital CPR Quality Improvement Project
The quality of cardiopulmonary resuscitation (CPR) provided to patients with out-of-hospital cardiac arrest (OHCA) is often suboptimal.
- Trial name
- NCT01258244
- Testing
- Audiovisual Feedback
- Where
- 2 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Valleywise Health
Epilepsy
Cardiac Rhythm Disturbances in Hard-to-treat Epilepsy Patients Using Loop ECG Recorders
Seizure-related cardiac arrhythmias are one of the possible causes of sudden unexpected death in epilepsy (SUDEP). Identification of these patients is challenging because cardiac rhythm disturbances could emerge only during…
- Trial name
- Epi-Loop-Rec (NCT03376087)
- Volunteers
- 193 people
- Sponsor
- National Research Center for Preventive Medicine
Myocardial Infarction
Characterization of Myocardial Infarction Scar Using Magnetic Resonance Imaging
The goal of this monocentric observationnal study is to describe the characteristics of the myocardial infarction scar in terms of transmurality in residual LVEF>35% patients.
- Trial name
- MI-SCAR-MRI (NCT05967026)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Congenital Heart Defects, Hypoplastic Left Heart Syndrome
Cerebral Perfusion During Neonatal Cardiac Surgery
Neonates with a congenital heart defect are often in need of early cardiac surgery. In complex congenital heart defects, cardiopulmonary bypass is usually employed, with or without deep hypothermic circulatory arrest (DHCA).
- Conditions
- Congenital Heart Defects, Hypoplastic Left Heart Syndrome, Aortic Coarctation
- Trial name
- NCT01032876
- Testing
- Deep Hypothermic Circulatory Arrest, Antegrade Cerebral Perfusion
- Where
- Netherlands
- Volunteers
- 37 people
- Sponsor
- UMC Utrecht
Cardiac Arrest
Prehospital Cerebral Oxygenation During Cardiopulmonary Resuscitation (CPR)
Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be…
- Trial name
- NCT01806844
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University
Cardiac Arrest, Cerebral Lesion
Early Transcranial Doppler Goal Directed Therapy After Cardiac Arrest: a Pilot Study
Hypoxic-ischaemic brain injury (HIBI) is the main cause of death in patients who are comatose after resuscitation from cardiac arrest.
- Conditions
- Cardiac Arrest, Cerebral Lesion, Ischemic Encephalopathy, Ischemic Reperfusion Injury
- Trial name
- GOODYEAR (NCT04000334)
- Testing
- MAP increased to optimize cerebral blood flow, MAP between 65 and 85 mmHg
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier le Mans
Cardiopulmonary Arrest, Nurse's Role
Mobile Micro-learning on Nurses' Self-confidence, Motivation, and Stress
Before and after effect of using mobile micro-learning on their self-confidence, motivation, and stress toward cardiopulmonary resuscitation.
- Trial name
- NCT06693232
- Testing
- Mobile micro-learning
- Where
- 2 sites in Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Cardiac Arrest
Effectiveness of an Interactive Cognitive Support Tablet App to Improve the Management of Pediatric Cardiac Arrest
Pediatric cardiac arrest (PCA) has a high mortality and morbidity. Its management is complex and often deviates from guideline recommendations leading to patients' worse clinical outcomes.
- Trial name
- PediAppRREST (NCT04619498)
- Testing
- PediAppRREST, AHA-PALS pocket reference card
- Where
- 4 sites in Italy
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Padova
Arrhythmias, Cardiac, Children, Only
Mobile Electrocardiogram Monitoring for Detecting Arrhythmias in Children
The objective of this project is to evaluate the capability of a specific mobile electrocardiogram monitoring of detecting arrhythmic events in children with history of palpitation and or syncope.
- Conditions
- Arrhythmias, Cardiac, Children, Only, Congenital Heart Disease, Sudden Cardiac Death
- Trial name
- NCT05140343
- Testing
- KARDIA Mobile ECG Monitoring (KMCM)
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Centro Medico Teknon
Sudden Cardiac Death
The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest
Sudden cardiac death (SCD) remains a major cause of mortality within developed nations despite aggressive efforts to reduce its societal burden.
- Trial name
- EPS ARREST (NCT03079414)
- Testing
- Invasive Electrophysiology Study
- Where
- 21 sites in United States, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- Western University, Canada
Out-Of-Hospital Cardiac Arrest
Machine Learning Assisted Recognition of Out-of-Hospital Cardiac Arrest During Emergency Calls.
Emergency medical Services Copenhagen has developed a machine learning model that analyzes the calls to 1-1-2 (9-1-1) in real time. The model are able to recognize calls where a cardiac arrest is suspected.
- Trial name
- NCT04219306
- Testing
- Alert on dispatchers screen 'Suspect cardiac arrest'
- Where
- Denmark
- Volunteers
- 5,242 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Heart Arrest, Implantable Defibrillator User
Effectiveness of Exercise After an ICD
This study will test an exercise intervention (E-ICD) following an implantable cardioverter defibrillator.
- Conditions
- Heart Arrest, Implantable Defibrillator User, Physical Activity
- Trial name
- E-ICD (NCT03544489)
- Testing
- E-ICD Intervention
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Washington
Cardiac Arrest, Endotracheal Intubation
Intubation During Pediatric Resuscitation
The European Resuscitation Council (ERC) 2010 cardiopulmonary resuscitation (CPR) guidelines suggest that intubators should be able to secure the airway without interrupting chest compression.
- Conditions
- Cardiac Arrest, Endotracheal Intubation, Pediatric Manikin
- Trial name
- NCT02277015
- Testing
- Miller Laryngoscope, The Berci-Kaplan DCI, The AirTraq
- Where
- Poland
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Left Ventricular Systolic Dysfunction, Sudden Cardiac Death
Heart Rate Response to Regadenoson and Sudden Cardiac Death
The purpose of this study is to determine whether a blunted heart rate response to regadenoson is an independent predictor of sudden cardiac death.
- Trial name
- NCT01842035
- Testing
- regadenoson
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Alabama at Birmingham
Brain Injury, Coma, Cardiac Arrest (CA)
Prediction for Coma Recovery With Comaweb
The general objective of the comaScore project is to provide an external validation of the accuracy of the comaScore, a score derived from magnetic resonance imaging (MRI), to predict 1 year outcome of patients unresponsive to…
- Conditions
- Brain Injury, Coma, Cardiac Arrest (CA), Traumatic Brain Injury (TBI), Aneurysmal Subarachnoid Hemorrhages (aSAH)
- Trial name
- COMASCORE (NCT03874208)
- Testing
- MRI sequence, MRI
- Where
- France
- Volunteers
- 611 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Arrest, Acute Coronary Syndrome
Mild Therapeutic Hypothermia for Patients With Acute Coronary Syndrome and Cardiac Arrest Treated With PCI
Mild Therapeutic Hypothermia for Patients with Acute Coronary Syndrome and Cardiac Arrest Treated with Percutaneous Coronary Intervention (UNICORN) study is designed to determine whether mild therapeutic hypothermia (MTH) applied…
- Trial name
- UNICORN (NCT02611934)
- Testing
- Mild Therapeutic Hypothermia (MHT)
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Jacek Kubica
Cardiac Arrest
Effects of Laryngeal Tube Ventilation on no Flow Time During Out of Hospital Cardiac Arrest
International recommendations stress on the importance of no flow time reduction in cardiac arrest management. In fact, no flow time is an independent factor of morbidity and mortality.
- Trial name
- FLOWERS (NCT01295749)
- Testing
- laryngeal tube ventilation and continuous chest compression
- Where
- 2 sites in France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Grenoble
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