Clinical trials: Atherogenic Dyslipidemia
Obesity, Dyslipidemia
Dose-Ranging Study Evaluating AVE1625 in Abdominally Obese Patients With Atherogenic Dyslipidemia
Primary objective: to assess the effect of AVE1625 on weight loss over a period of 24 weeks in abdominally obese patients with atherogenic dyslipidemia.
- Trial name
- NCT00345410
- Testing
- AVE1625 B
- Where
- United States
- Volunteers
- 345 people
- Sponsor
- Sanofi
Diabetes Mellitus Type 2, Hypercholesterolemia
Effect of Ezetimibe or Simvastatin or Both on Low Densitiy Lipoprotein -Subfractions in Patients With Type 2 Diabetes
It is of interest how ezetimibe alone or in combination with statin may influence atherogenic dense Low Density Lipoprotein (dLDL) in patients with type 2 diabetes mellitus.
- Trial name
- EZE (NCT01384058)
- Testing
- ezetimibe, simvastatin, Ezetimibe 10/Simvastatin 20
- Where
- 2 sites in Germany
- Volunteers
- 41 people
- Sponsor
- University Hospital Freiburg
Metabolic Syndrome x
The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study
Patients with metabolic syndrome, insulin resistance, and elevated triglycerides of 150 mg/dl or higher will be randomized to one of four groups: 1) placebo; 2) metformin; 3) fenofibrate; or 4) combined metformin and fenofibrate…
- Trial name
- NCT00400231
- Testing
- Study drugs: Metformin and fenofibrate, Study Drug: Metformin, Study Drug: fenofibrate
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cardiovascular Disease, Dyslipidemia
Dietary Protein Sources and Atherogenic Dyslipidemia
There is growing epidemiological evidence that consumption of red meat is associated with greater incidence of Cardiovascular Disease (CVD) than either white meat or non-meat foods.
- Conditions
- Cardiovascular Disease, Dyslipidemia, Insulin Resistance, Inflammation
- Trial name
- NCT01427855
- Testing
- High saturated fat red meat diet, High saturated fat non-meat diet, High saturated fat white meat diet
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Atherogenic Dyslipidemia, Obesity Associated Disorder
Extended Release Niacin and Fenofibrate for the Treatment of Atherogenic Dyslipidemia in Obese Females
Atherogenic Dyslipidemia (AD) is a risk-conferring lipid/lipoprotein profile that comprises a higher proportion of small LDL particles, reduced HDL-C, and increased triglycerides.
- Trial name
- NCT03615534
- Testing
- Therapeutic Lifestyle Changes, Fenofibrate, Wax Matrix Extended Release Niacin (WMER Niacin)
- Where
- 2 sites in Iraq
- Volunteers
- 161 people
- Sponsor
- Lewai Sharki Abdulaziz, MSc PhD
Ischemic Stroke
Atherogenic Lipoproteins in Ischemic Stroke
Apolipoprotein B (apoB) levels (which encompass all atherogenic lipoproteins, including LDL), Lp(a) levels, and carotid IPH are associated with both first-ever and recurrent ischemic stroke.
- Trial name
- AGELESS (NCT05090878)
- Where
- 2 sites in Switzerland
- Volunteers
- 500 people
- Sponsor
- University Hospital, Basel, Switzerland
Dyslipidemia
Hs-CRP as Clinical Marker of Inflammatory Atherogenic Dyslipidemia
The objective of this proposal is to study the applicability of the hs-CRP assay in the assessment of CV risk in daily clinical conditions where hyperlipidemic population with or without CHD are currently evaluated.
- Trial name
- NCT00169871
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Healthy, Cardiovascular Disease
Resistant Starch Insulin Sensitivity Trial
The alarming increase in the prevalence of obesity is a cause of great concern given its association with many adverse health conditions, including insulin resistance and type 2 diabetes, which are associated with increased…
- Conditions
- Healthy, Cardiovascular Disease, Atherogenic Dyslipidemia, Insulin Resistance
- Trial name
- RESIST (NCT01027325)
- Testing
- Dietary Intervention
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Healthy, Cardiovascular Disease
Relation of Diet to Heart Disease Risk Factors in Children
Metabolites of dietary phosphatidylcholine- choline and trimethylamine N-oxide (TMAO)- were recently identified as being associated with myocardial infarction in a case-control study.
- Trial name
- NCT01418196
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Dyslipidemia, Obesity, Abdominal
Effects of Almond Intake on Atherogenic Lipoprotein Particles
Increased abdominal adiposity is a key feature of metabolic syndrome, which describes a cluster of cardiovascular disease (CVD) risk factors that also includes insulin resistance, high blood pressure and an atherogenic…
- Trial name
- NCT01792648
- Testing
- Standard reference diet, Almond supplemented diet, Low carbohydrate reference diet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Insulin Resistance, Hypertriglyceridemia
Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides.
Approximately 1/4 of the US population has insulin resistance and the associated risk factors such as elevated lipid levels -triglycerides (type of fat from what we eat and what the liver produces and low HDL cholesterol which is…
- Trial name
- NCT00186537
- Testing
- Rosiglitazone, Fenofibrate, Weight Loss
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Stanford University
Metabolic Syndrome, Atherogenic Dyslipidemia
The Dose-response Effects of High Intensity Functional Training on Metabolic Syndrome Risk Factors
This study aims to explore the dose effects of three weekly volumes of high-intensity functional training (HIFT) on apolipoprotein B (ApoB), triglyceride (TG) and cholesterol (CHOL) content of low-density lipoproteins (LDL), very…
- Conditions
- Metabolic Syndrome, Atherogenic Dyslipidemia, Insulin Resistance, Endothelial Dysfunction
- Trial name
- NCT05001126
- Testing
- HIFT 1x/week, HIFT 2x/week, HIFT 3x/week
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Gary Van Guilder
Dyslipidemia
Effects of Niacin On Fatty Acid Trapping
The purpose of this study is to understand whether a vitamin called NIcotinic ACid vitamIN (NIACIN for short, also known as vitamin B3) helps the body process dietary fat more efficiently.
- Trial name
- NOFAT (NCT01984073)
- Testing
- ER Niacin Oral Fat Challenge, IR Niacin Oral Fat Challenge
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Pennsylvania
Lipid Metabolism Disorders, Hypertriglyceridemia
Differential Thrombogenesis by EPA and DHA Mediated by HDL
The goal of this study is to learn more about omega-3 polyunsaturated fatty acids supplementation on blood lipid profile and platelets in patients with high cholesterol levels.
- Trial name
- NCT06494488
- Testing
- EPA, DHA
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Miriam Hospital
Dyslipidemias, Coronary Heart Disease
Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood
The primary purpose of this study is to compare the safety and efficacy of ABT-335 (investigational drug) coadministered with atorvastatin and ezetimibe to atorvastatin coadministered with ezetimibe in subjects with abnormal…
- Conditions
- Dyslipidemias, Coronary Heart Disease, Combined (Atherogenic) Dyslipidemia, Mixed Dyslipidemia
- Trial name
- NCT00639158
- Testing
- ABT-335, atorvastatin, ezetimibe
- Where
- 118 sites in United States
- Volunteers
- 543 people
- Sponsor
- Abbott
Dyslipidemias
Effect of Niacin on Transport of HDL and Relationship to Atherogenic Lipoproteins and Lipolysis
This study looks at whether niacin improves reverse cholesterol transport (RCT) in healthy volunteers. 3H-Cholesterol will be used to measure RCT by analyzing changes in the tracer activity in total plasma, lipoproteins, red…
- Trial name
- ENTHRALL (NCT01250990)
- Testing
- Niacin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Metabolic Syndrome
Effect of a Low Advanced Glycation End Products (AGE) Diet in the Metabolic Syndrome
The investigators have previously demonstrated that Advanced Glycation End products (AGEs) are associated with several chronic diseases in humans and that blood AGE levels can be significantly reduced by simply changing the way…
- Trial name
- NCT01363141
- Testing
- Regular AGE Diet, Low AGE Diet
- Where
- United States
- Volunteers
- 383 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Disorder Associated With Menstruation and/or Menopause, Dyslipidemia
The Roles of SAH Gene Family in Athrogenic Dyslipidemia in Postmenopausal Women
Atherogenic dyslipidemia is characterized by high levels of apolipoprotein B (apoB)-containing lipoproteins, including very-low-density lipoprotein (VLDL) and its remnants and small, dense LDL (sdLDL) particles, and reduced…
- Trial name
- MOSAH-S2 (NCT00945217)
- Where
- Taiwan
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Dyslipidemia
A Study in People With Abnormal Fat Levels in the Blood
The purposes of this study are to determine: The safety of the study medication and any side effects that might be associated with it; Whether the study medication can help patients with low levels of 'good' cholesterol (HDL-C)…
- Trial name
- NCT00116519
- Testing
- PPAR alpha
- Where
- 54 sites in United States
- Volunteers
- 300 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Inflammation
Egg Effects on Atherogenic Dyslipidemias, Glucose Metabolism and Inflammation in Diabetic Subjects
There is concern in the literature regarding egg consumption in diabetic people. The investigators hypothesis is that compared to an oatmeal-based breakfast, an egg-based breakfast will not increase the risk for heart disease in…
- Trial name
- NCT02181244
- Testing
- Egg, one a day, for breakfast, Oatmeal, one cup a day
- Where
- Mexico
- Volunteers
- 33 people
- Sponsor
- University of Connecticut