Clinical trials: Atopic Dermatitis (Eczema)
Atopic Dermatitis
Clinical Trial to Evaluate the Effect of a Probiotic Mixture in the Treatment of Atopic Dermatitis in Children
A prospective case-control multicentric pilot study of 12 weeks duration to evaluate the effect of a probiotic mixture in the treatment of atopic dermatitis in children from 0 to 3 years old, by measuring the severity of the…
- Trial name
- NCT05443490
- Testing
- Probiotic mixture with three bacterial strains with maltodextrin as a carrier.
- Where
- 3 sites in Bolivia, Costa Rica and 1 more
- Volunteers
- 4 people
- Sponsor
- Bionou Research, S.L.
Atopic Dermatitis, Eczema
The Utility of Functionally Relevant Signature Genes in Assessing the Clinical Outcomes of Dupilumab Treatment
The utility of functionally relevant signature genes in assessing the clinical outcomes of dupilumab treatment in the adult onset atopic dermatitis
- Trial name
- NCT04358224
- Testing
- Dupilumab Prefilled Syringe
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Jonathan A. Bernstein, MD
Nummular Eczema
Study of Dupilumab to Demonstrate Efficacy in Subjects With Nummular Eczema
Nummular eczema (NE) is an idiopathic chronic inflammatory skin disease that occurs throughout all life periods. Diagnosis is made primarily clinically in correlation with histological findings. Treatment of NE is difficult.
- Trial name
- DUPINUM (NCT04600362)
- Testing
- Experimental: Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT]
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Technical University of Munich
Atopic Dermatitis
Methodological Study of the Effect of a Lotion Containing Nature Based Microbial Extract on Atopic Skin
The purpose of the study is to test the selected methods and to explore the effect of nature-based exposure on immunological biomarkers and the condition of atopic skin.
- Trial name
- NCT06499766
- Testing
- Biodiversity intervention by inactivated microbial extract
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- Uute Scientific Oy
Atopic Dermatitis, Eczema Herpeticum
Identifying Risk Factors for Eczema Herpeticum in Individuals With Atopic Dermatitis
Atopic Dermatitis (AD), also known as eczema, is a skin disease that causes the skin to be hot, dry and scaly, and have severe itching. There are different kinds of eczema.
- Trial name
- NCT00438022
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Atopic Dermatitis, Eczema-Prone Skin
Skin Efficacy and Tolerability of a Cosmetic Product Combination Over 3 Months in Subjects With Atopic Eczema
The aim of this exploratory study is to investigate the short- and long-term efficacy and tolerability of a cosmetic product combination consisting of a body lotion and an intensive care product in subjects with atopic eczema…
- Trial name
- AtoCare-OS (NCT05790083)
- Testing
- Body Lotion and Intensive Care
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bionorica SE
Atopic Dermatitis
Randomized Placebo Controlled Study to Determine Safety, Pharmacodynamics and Efficacy of ILV-094 in Atopic Dermatitis
Atopic dermatitis (AD) is a common inflammatory skin disorder that adversely affects most aspects of everyday life in majority of patients. It has a prevalence of up to 3-4% of adults and up to 25% among children.
- Trial name
- NCT01941537
- Testing
- ILV-094
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rockefeller University
Healthy Adults, Atopic Dermatitis
Sweat and Gas Sensor for Healthy Skin and Atopic Dermatitis
Pilot study of a wearable gas and sweat skin sensor
- Conditions
- Healthy Adults, Atopic Dermatitis, Wearables, Sweat Sensor
- Trial name
- NCT03874039
- Testing
- Gas sensor, Sweat Sensor
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atopic Dermatitis
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
The main aim of the study is to assess real-world effectiveness of nemolizumab in Atopic Dermatitis (AD) as measured by physician assessment and patient reported outcome (PRO) in clinical practice at Month 6.
- Trial name
- RE-UNITE AD (NCT06988605)
- Where
- 108 sites in United States, Germany and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Galderma R&D
Eczema, Atopic Dermatitis
Bilateral Comparison Study of Elidel 1% and Hylatopic Plus Emollient Foam for the Treatment of Subjects With Atopic Dermatitis
This is an investigator-blinded, bilateral comparison study in 30 subjects with atopic dermatitis. It is designed to assess and compare the efficacy of Elidel® (pimecrolimus) cream 1% and Hylatopic™ Plus Emollient Foam™ in…
- Trial name
- NCT01202149
- Testing
- Elidel (pimecrolimus cream, 1%) Hylatopic Plus Emollient Foam (non-medicated device)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Frankel, Amylynne, M.D.
Atopic Dermatitis
A Study Evaluating TRIV-509 in Atopic Dermatitis
The goal of this interventional study is to learn if TRIV-509 works to treat moderate to severe atopic dermatitis in adults. It will also evaluate the safety of TRIV-509.
- Trial name
- NCT07167758
- Testing
- TRIV-509
- Where
- 32 sites in United States, Bulgaria and 5 more
- Volunteers
- 95 people
- Sponsor
- Triveni Bio
Microbial Colonization, Atopic Dermatitis
Nationwide Research on the Rewilding of Kindergarten Yards
Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity in cities that is associated with altered commensal microbiota and a rising burden of immunological disorders among urban children.
- Conditions
- Microbial Colonization, Atopic Dermatitis, Asthma in Children, Allergy
- Trial name
- Vahvistu (NCT06390878)
- Testing
- Biodiversity, Playground equipment
- Where
- 2 sites in Finland
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Natural Resources Institute Finland
Atopic Dermatitis
Cognitive Behavior Therapy for Atopic Dermatitis
Atopic dermatitis is an inflammatory skin disease characterized by itching, dry skin and recurrent inflammatory eczema. It is one of the most common skin diseases and is associated with reduced quality of life, functional…
- Trial name
- NCT02302625
- Testing
- Cognitive behavior therapy
- Where
- Sweden
- Volunteers
- 9 people
- Sponsor
- Karolinska Institutet
Atopic Dermatitis
Induced Pluripotent Stem Cell Derived Exosomes for the Treatment of Atopic Dermatitis
Evaluate the safety, tolerability, and preliminary efficacy of GD-iExo-001 in the treatment of atopic dermatitis
- Trial name
- NCT05969717
- Testing
- GD-iExo-001, normal saline
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking Union Medical College Hospital
Atopic Dermatitis
Photophoresis Versus Ciclosporine in Severe Atopic Dermatitis
Severe atopic dermatitis (AD) is a recurrent and debilitating disease often requiring systemic immunosuppressive treatment. The efficacy of cyclosporine A (CsA) is well proven but potential side effects are concerning.
- Trial name
- NCT02226068
- Testing
- Cyclosporine A (CsA), Extracorporeal photopheresis (ECP)
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Moderate to Severe Atopic Dermatitis
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
The purpose of this study is to evaluate the study drug, SYX-5219, in a multi-part First-in-Human (FiH) study to be conducted in healthy volunteers and participants with Atopic Dermatitis (AD).
- Trial name
- NCT07558668
- Testing
- SYX-5219 Oral Capsule
- Where
- 14 sites in United States, Bulgaria and 4 more
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Sitryx Therapeutics Ltd
Eczema
Randomized Controlled Trial of an Eczema Care Plan
The objectives of this project are to increase families' understanding of eczema and improve eczema management in the primary care setting. We have created an "Eczema Care Plan" similar to those used in the management of asthma.
- Trial name
- NCT02251340
- Testing
- Eczema Care Plan
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Boston Children's Hospital
Atopic Dermatitis
A Phase Ⅲ Comparative Study of QL2108 to Dupixent®
It is a multicenter randomized, double-blinded, parallel, positive-controlled, Phase Ⅲ comparative study to evaluate the efficacy and safety of QL2108 to Dupixent® in adult subjects with moderate-to-severe atopic dermatitis.
- Trial name
- NCT06884891
- Testing
- QL2108 injection, Dupixent®
- Volunteers
- 520 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Atopic Dermatitis (Eczema), Atopic Dermatitis, Probiotics
Prebiotic Effects of Mulberry Fruit in Children and Adolescents With Atopic Dermatitis
This project proposes a randomized controlled human study to explore the prebiotic effects of consuming mulberry juice on atopic dermatitis in children and adolescents.
- Trial name
- NCT06636240
- Testing
- Mulberry fruit juice, Mometasone furoate 0.1% cream
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Eczema, Atopic Dermatitis
The Impact of Dietary Salt on the Severity of Eczema
The goal of this clinical trial is to evaluate the feasibility of low-sodium diet to improve eczema severity. The main questions it aims to answer are: Does a low-sodium diet improve eczema severity? How does a low-sodium diet…
- Trial name
- iDOSE (NCT07447063)
- Testing
- Sodium chloride tablets
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
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