Clinical trials: Atrial Fibrillation
Deep Vein Thrombosis Leg, Stroke (in Patients With Atrial Fibrillation)
A Healthy Volunteer Study to Investigate the Blood Concentrations, the Effect on Blood Clotting and the Safety of Multiple Doses of DPOC-4088 Tablets in Different Doses.
A study to investigate the concentrations of a new drug DPOC-4088 in blood, and to study the effect of this drug on blood clotting parameters.
- Trial name
- NCT01647620
- Testing
- DPOC-4088
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Diakron Pharmaceuticals
Cardiovascular Diseases, Heart Failure
Longitudinal Validation of CIRC Technologies
Cardiovascular disease is the leading cause of death worldwide. Advanced cardiovascular imaging using Magnetic Resonance Imaging (MRI) has proven to be effective in providing gold standard myocardial tissue characterization.
- Conditions
- Cardiovascular Diseases, Heart Failure, Ischemic Heart Disease, Non-ischemic Cardiomyopathy
- Trial name
- NCT07081711
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Paroxysmal Atrial Fibrillation
Atrial Electromechanical Function in Endurance Athletes With and Without Atrial Fibrillation
This study evaluates cardiac structure and function differences between healthy endurance trained athletes with atrial fibrillation and healthy age matched endurance trained athletes without atrial fibrillation.
- Trial name
- NCT03305744
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Volunteers
Safety and Pharmacokinetic Study of OMT-28 in Healthy Subjects
The aim of this first-in-human study is to assess the safety, tolerability, PK and exploratory pharmacodynamics (PD) of single and multiple oral ascending doses of OMT-28 in healthy male subjects to support further clinical…
- Trial name
- NCT03078738
- Testing
- OMT-28
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Omeicos Therapeutics GmbH
Nonvalvular Atrial Fibrillation, Health, Subjective
Pharmacokinetic Study to Evaluate Dabigatran Etexilate in Elderly Subjects
This study intends to collect blood samples of adult healthy subjects, elderly healthy subjects and elderly patients with atrial fibrillation after taking dabigatran etexilate for pharmacokinetics and other studies, aiming to…
- Trial name
- NCT05715658
- Testing
- Dabigatran etexilate capsule
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dongyang Liu
Atrial Fibrillation
Blinded Randomized Controlled Trial of Artificial Intelligence Guided Detection of Intracardiac Thrombus
To determine whether an integrated AI decision support can save time and improve the accuracy of detection of intracardiac thrombus, the investigators are conducting a blinded, randomized controlled study of AI-guided detection…
- Trial name
- NCT06206187
- Testing
- Automated detection of the intracardiac thrombus through deep learning, Electrophysiologist judgment of the intracardiac thrombus
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation Paroxysmal
Prospective Validation Study of AI-based Prediction Algorithm for the Prediction of Paroxysmal Atrial Fibrillation
The purpose of this study is to predict the occurrence of paroxysmal atrial fibrillation by finding high-risk group from normal sinus rhythm ECG through artificial intelligence-based prediction algorithm.
- Trial name
- PROVISION-AF (NCT05725187)
- Testing
- MobiCare
- Where
- 11 sites in South Korea
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital
Atrial Fibrillation, Heart Failure, Systolic
Machine Learning Enabled Time Series Analysis in Medicine
The goal of this observational cohort study is to investigate the potential of fitness trackers in combination with machine learning algorithms to identify cardiovascular disease specific patterns.
- Trial name
- ME-TIME (NCT05802563)
- Testing
- fitness tracker
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- HagaZiekenhuis
Atrial Fibrillation
Cohort Study for Atrial Fibrillation Risk Stratification
AFHRI is planned as a prospective, single-center cohort study in patients at high risk of AF.
- Trial name
- AFHRI (NCT05442970)
- Where
- Germany
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atrial Fibrillation New Onset
Promoting Atrial Fibrillation Screening in Primary Care
Atrial fibrillation is the most common sustained cardiac arrhythmia in adults. Due to the asymptomatic and paroxysmal nature (randomly and shortly occurring of atrial fibrillation, and can therefore remain unnoticed) of atrial…
- Trial name
- NCT06458829
- Testing
- SEARCH-AF
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Atrial Fibrillation
SL-AF Trial - (Six Lead Identification of Atrial Fibrillation [AF])
The 12-lead ECG is an essential tool in cardiovascular assessment. Novel technology has the potential to improve the diagnostic yield of arrhythmias, whilst improving the patient experience.
- Trial name
- SL-AF (NCT02401451)
- Testing
- RhythmPadGP
- Where
- United Kingdom
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Cardiocity Limited
Atrial Fibrillation
WIBOFA - Validation of SCT02 With ECG-App for Detection of AF
The aim of the study is to evaluate the performance of Withings SCT02 with embedded Withings ECG-app in the automatic detection of atrial fibrillation
- Trial name
- WIBOFA (NCT06351761)
- Testing
- Investigational Device (Withings SCT02) 30 second Electrocardiogram recording, Reference Device (Schiller Cardiovit FT-1) 30 second Electrocardiogram recording
- Where
- 4 sites in United States, France
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- Withings
Atrial Fibrillation; Stroke Prevention
Stroke Prevention in Atrial Fibrillation Patients Between 2004 and 2020
Prevention of thromboembolic complications is an important part in the management of patients with atrial fibrillation (AF). European and American guidelines recommend the use of non-vitamin K antagonist oral anticoagulants…
- Trial name
- NCT04686045
- Testing
- observational study
- Where
- 2 sites in Poland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Jan Kochanowski University
Athlete Heart
Prospective Athlete's Heart Study
The Pro@Heart (Prospective Athlete's Heart) study is an international multicentre long-term prospective trial. The primary objective of the Pro@Heart study is to investigate the impact of training load (i.e.
- Trial name
- Pro@Heart (NCT05164328)
- Testing
- No intervention
- Where
- 4 sites in Australia, Belgium
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Ventricular Tachycardia, Atrial Fibrillation
Defining the Risk of Ventricular Tachycardia in Genetic Forms of Early-onset Atrial Fibrillation
To use programmed ventricular stimulation at the time of AF ablation to define the prevalence and mechanism of inducible ventricular tachycardia (VT); pace-mapping to define the site of origin of ventricular arrhythmias; and…
- Trial name
- NCT06647459
- Testing
- EP Study
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cardiac Arrhythmia, Atrial Fibrillation
Diagnostic Accuracy of WEARable TECHnology Single-lead ECG in Detecting Cardiac Arrhythmias
Atrial fibrillation (AF) is the most common arrhythmia (irregular heart rhythm), affecting 1-2 million people in the UK. AF significantly increases the risk of an AF-related stroke, heart failure and dementia.
- Trial name
- WEAR-TECH ECG (NCT05298553)
- Testing
- Group A, Group B
- Where
- 3 sites in United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Atrial Fibrillation
Program for the Identification of "Actionable" Atrial Fibrillation in the Family Practice Setting
Atrial fibrillation (AF) is a major risk factor for stroke. The identification and treatment of AF is one of the best way to prevent stroke.
- Trial name
- PIAAF-FP (NCT02262351)
- Testing
- 30 Second Pulse Check, Watch BP Home A, HeartCheck Hand-held ECG device
- Where
- 19 sites in Canada
- Volunteers
- 2,174 people, healthy volunteers welcome
- Sponsor
- Population Health Research Institute
Asymptomatic Atrial Fibrillation
Subclinical Atrial Fibrillation Home Monitoring in Hypertensive Patients
Atrial fibrillation is a highly prevalent and incidental arrhythmia, often asymptomatic, and frequently detected incidentally or in association with a stroke.
- Trial name
- NCT07058831
- Testing
- Home ECG monitoring
- Where
- Argentina
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Research Center Rosario British Sanatorium