Clinical trials: Atrial Fibrillation, completed
Foramen Ovale, Patent, Echocardiography
Long-term Outcomes After Percutaneous Closure of PFO
International medical centre Medicor from Slovenia has reported 363 successful percutaneous closures of patent foramen ovale (PFO) from October 2006 till October 2023.
- Conditions
- Foramen Ovale, Patent, Echocardiography, Embolic Stroke, Atrial Fibrillation
- Trial name
- NCT05558774
- Where
- Slovenia
- Volunteers
- 364 people
- Sponsor
- MC Medicor
Atrial Fibrillation (AF)
Cardiac Rehabilitation Needs Among Individuals With Atrial Fibrillation
The goal of this survey- and registry-based study is to learn about the cardiac rehabilitation needs of individuals with atrial fibrillation (AF). The main objectives of the study is to: 1.
- Trial name
- PRIME-AF (NCT06772207)
- Where
- Denmark
- Volunteers
- 30,882 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Atrial Fibrillation; Paroxysmal Atrial Fibrillation; Persistent Atrial Fibrillation
Pulsed Field Ablation of Atrial Fibrillation: CENTAURI Versus FARAPULSE
The aim of this study is to compare the efficacy of two commercially available pulsed field ablation (PFA) systems for catheter ablation of atrial fibrillation.
- Trial name
- NCT07902739
- Testing
- CENTAURI PEF system, FARAPULSE system
- Where
- Czechia
- Volunteers
- 325 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Atrial Fibrillation
High-Intensity Aerobic Lifelong Training--AF
This study is a single-center RCT. Potential subjects with symptomatic non-permanent AF will be enrolled to determine the effect of sprint interval training (SIT) in comparison to moderate-intensity continuous training (MICT) and…
- Trial name
- HALT-AF (NCT03241433)
- Testing
- High intensity interval training, Moderate intensity continuous training, No Exercise
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Minnesota
Atrial Fibrillation
Coherent Sine Burst (CSE) Electroporation System Pilot Study in Patients With Atrial Fibrillation
To evaluate the safety and efficiency of the Arga Medtech CSE Ablation System in the treatment of atrial fibrillation.
- Trial name
- BURST-AF (NCT05572047)
- Testing
- Arga Medtech Coherent Sine-Burst Electroporation (CSE) Ablation System
- Where
- 3 sites in Croatia, Georgia
- Volunteers
- 101 people
- Sponsor
- Arga Medtech SA
Atrial Fibrillation (AF), Acute Kidney Injury
Peri-procedural Hydration to Prevent Acute Kidney Injury After Pulsed Field Ablation for Atrial Fibrillation
PFA is an emerging non-thermal ablation technology with favorable procedural safety; however, recent studies have raised concerns about peri-procedural hemolysis and subsequent AKI after PFA.
- Trial name
- HYDRATE-PFA (NCT07490808)
- Testing
- 0.9% sodium chloride
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation Paroxysmal
Pulsed Field Ablation vs Cryoablation In Paroxysmal Atrial Fibrillation
Cryoballoon pulmonary vein isolation (PVI) has emerged as an alternative to radiofrequency in the treatment of drug-resistant atrial fibrillation (AF).
- Trial name
- FACIL AF (NCT05940597)
- Testing
- Pulse field ablation, Cryoballoon pulmonary vein isolation
- Where
- 7 sites in France
- Volunteers
- 354 people
- Sponsor
- University Hospital, Grenoble
Paroxysmal Atrial Fibrillation
STOP AF First Post-Approval Study
The STOP AF First PAS is a prospective, global, multi-center, observational trial.
- Trial name
- NCT05227053
- Testing
- Arctic Front™ Cardiac Cryoablation Catheter
- Where
- 11 sites in United States
- Volunteers
- 142 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Patent Foramen Ovale, Atrial Fibrillation
Prevalence of Atrial Fibrillation in Cryptogenic Stroke With Patent Foramen Ovale Closure (PFO-AF) Study
This study aims to assess the incidence of atrial fibrillation (AF), documented using data recorded by an implantable Holter monitoring device (Reveal Linq, Medtronic) within 2 years after percutaneous closure of patent foramen…
- Conditions
- Patent Foramen Ovale, Atrial Fibrillation, Stroke
- Trial name
- PFO-AF (NCT04926142)
- Testing
- Implantation of Holter device, Percutaneous PFO closure
- Where
- 4 sites in France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Atrial Fibrillation, Fibrosis Myocardial
Atrial Fibrillation Driver Study
Atrial Fibrillation (AF) is an abnormal rhythm of the heart which is increasingly common and can be associated with serious consequences.
- Trial name
- NCT05743829
- Testing
- Tissue excision as part of routine clinical care
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Atrial Fibrillation
Randomised Comparison of the Octaray and Pentaray Catheters
In this study we aim to compare the mapping performance in the left atrium of the established Pentaray catheter to the newer Octaray catheter.
- Trial name
- COPEC (NCT05988424)
- Testing
- Left atrial mapping
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Atrial Fibrillation
Pharmacokinetics of Apixaban in Peritoneal Dialysis
Atrial fibrillation (AF) is fairly prevalent in patients with end stage renal disease (ESRD) with the prevalence estimated to be 3.8 - 27%.
- Trial name
- NCT05532878
- Testing
- Apixaban
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Atrial Fibrillation, Atrial Cardiomyopathy
Clinical Cohorts for Validation of New Digital Biomarkers
The MAESTRIA study is an international, multi-centre, non-interventional, observational registry. The main goal is to enrol a representative group of European patients diagnosed with Atrial Fibrillation (AF) to analyse clinical…
- Trial name
- MAESTRIA (NCT05855538)
- Where
- Germany
- Volunteers
- 515 people
- Sponsor
- Atrial Fibrillation Network
Atrial Tachycardia
The RIPPLE AT-PLUS Study
Atrial tachycardia is a symptomatic arrhythmia, for which an effective treatment is a catheter ablation procedure. The goal of the Ripple AT-Plus study is to evaluate two methods of performing catheter ablation for atrial…
- Trial name
- NCT03915691
- Testing
- Catheter ablation of atrial tachycardia: Ripple Mapping guided., Catheter ablation of atrial tachycardia: Conventional mapping guided.
- Where
- 3 sites in United Kingdom
- Volunteers
- 201 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Atrial Fibrillation, Atrial Flutter
Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)
The prevention of perioperative atrial fibrillation (AF) and myocardial injury after non-cardiac surgery (MINS) has the potential to reduce mortality, stroke, and hospital stays in patients undergoing major thoracic surgery.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Myocardial Injury After Non-Cardiac Surgery
- Trial name
- COP-AF (NCT03310125)
- Testing
- Active Colchicine
- Where
- 46 sites in United States, Austria and 9 more
- Volunteers
- 3,209 people
- Sponsor
- Population Health Research Institute
Atrial Fibrillation
A Study of the THERMOCOOL SMARTTOUCH Surround Flow (SF) Catheter With the TRUPULSE Generator for Treatment of Drug Refractory Symptomatic PAFOUS
The purpose of this study is to demonstrate safety and effectiveness of the Biosense Webster (BWI) ablation system (THERMOCOOL SMARTTOUCH surround flow [STSF] catheter and TRUPULSE generator) when used for isolation of the atrial…
- Trial name
- PulseSmart (NCT06272981)
- Testing
- Pulsed Field (PF) /Radiofrequency (RF) Catheter ablation
- Where
- 7 sites in Australia, Canada
- Volunteers
- 136 people
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation, Patient Engagement
Data-driven SDM to Reduce Symptom Burden in AF
This study is a single-group feasibility study evaluating decision aid visualizations which display common post-ablation symptom patterns as a tool for shared decision-making.
- Trial name
- NCT04993807
- Testing
- Shared decision-making tool
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Columbia University
Arrhythmias, Cardiac, Atrial Fibrillation
To Compare and Evaluate the Efficacy and Safety Between TS-RF System and BRK Transseptal Needles Used for Transseptal Puncture for Left Atrial Access.
The purpose of this study is to compare and assess efficacy and safety between the study device "TS-RF system consisting of a electrosurgical system, general-purpose (TS-RF Generator) and a electrosurgical system electrode…
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Heart Diseases
- Trial name
- NCT06358391
- Testing
- TS-RF Transseptal Needle, BRK Transseptal Needle
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Starmed
Atrial Fibrillation, Inflammation
Inflammation and Postoperative Atrial Fibrillation in Cardiac Surgery
Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery, marked by an irregular and rapid heart rate, and associated with increased morbidity, longer hospital stays, and higher costs.
- Trial name
- NCT06475547
- Testing
- Descriptive
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Odense University Hospital
Atrial Fibrillation, Renal Dysfunction
A Real World Evidence Retrospective Data Collection Study of Edoxaban and Rivaroxaban
This study aims to evaluate the recommended once-daily dosing of edoxaban and rivaroxaban in patients with atrial fibrillation (AF) and renal dysfunction in South Korea and Taiwan.
- Trial name
- NCT07874555
- Testing
- Edoxaban, Rivaroxaban
- Where
- 2 sites in South Korea, Taiwan
- Volunteers
- 8,265 people
- Sponsor
- Daiichi Sankyo