Clinical trials: Atrial Fibrillation Catheter Ablation
Atrial Fibrillation, Thromboembolism
Investigation on Appropriate Duration of Dabigatran Use After Catheter Ablation for Paroxysmal Atrial Fibrillation in Patients With Low Thromboembolic Risk
The purpose of this study is to investigate the appropriate duration of dabigatran use after radiofrequency catheter ablation for paroxysmal atrial fibrillation in patients with low thromboembolic risk.
- Trial name
- NCT02313584
- Testing
- dabigatran
- Volunteers
- 464 people
- Sponsor
- Korea University
Atrial Fibrillation
Characterisation of Fractionated Electrograms Critical for Maintenance of Atrial Fibrillation (AF)
The purpose of this study is to characterise which fractionated electrogram morphologies are important to target in the catheter ablation of atrial fibrillation.
- Trial name
- CAFE AF (NCT00894400)
- Testing
- catheter ablation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Barts & The London NHS Trust
Atrial Fibrillation (AF)
Epicardial Adipose Tissue-Targeted DApagliflozin for Reducing Electrical Remodeling in Atrial Fibrillation
Persistent atrial fibrillation (PeAF) is associated with a high risk of recurrence following catheter ablation despite advances in ablation technology and strategies.
- Trial name
- EAT-DARE-AF (NCT07331727)
- Testing
- Dapagliflozin (10Mg Tab) along with standard medical therapy
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shanghai Chest Hospital
Arrhythmia
The Effect of Additional Propacetamol Infusion on Post Procedural Outcome and Opioid Consumption During Catheter Ablation of Atrial Fibrillation.
Sedation for catheter ablation of atrial fibrillation should be performed to achieve analgesia, immobilization, and maintenance of airway.
- Trial name
- NCT02515188
- Testing
- Propacetamol
- Where
- South Korea
- Volunteers
- 98 people
- Sponsor
- Yonsei University
Atrial Fibrillation
Apple Watch-led Surveillance of AF Recurrence After Catheter Ablation
Atrial fibrillation (AF) is a heart rhythm disorder associated with debillitating symptoms, psychological distress and heart failure. It can also significantly increase an individuals stroke risk.
- Trial name
- AFFU-AW (NCT05016791)
- Testing
- Apple Watch-based heart rhythm monitoring
- Where
- United Kingdom
- Volunteers
- 172 people
- Sponsor
- Barts & The London NHS Trust
Atrial Fibrillation, Quality of Life
Catheter Ablation Compared With Pharmacological Therapy for Atrial Fibrillation (CAPTAF Trial)
The objective is to compare the efficacy of 2 treatment strategies, catheter ablation of atrial fibrillation versus optimized pharmacological therapy, in patients with symptomatic atrial fibrillation.
- Trial name
- CAPTAF (NCT02294955)
- Testing
- Catheterablation, Amiodarone, Sotalol
- Where
- Sweden
- Volunteers
- 152 people
- Sponsor
- Uppsala University Hospital
Atrial Fibrillation
Comparison of 3 RF Delivery Modes of the QDOT Catheter for Paroxymal Atrial Fibrillation (AF) Ablation
Pulmonary vein isolation is the main treatment of paroxysmal and persistent atrial fibrillation. The aim of our study is to prospectively compare the efficacy and safety of the 3 options of radiofrequency delivery with QDOT…
- Trial name
- QDOT (NCT06647251)
- Testing
- Q-MODE : radiofrequency ablation up to 50W, Q-MODE+ : radiofrequency up to 90W, Hybride Q-MODE/Q-MODE+: radiofrequency ablation up to 50W in the anterior part, and 90W in the posterior part
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Institut Mutualiste Montsouris
Paroxysmal Atrial Fibrillation
TactiCath Contact Force Ablation Catheter Study for Atrial Fibrillation
The TOCCASTAR Study will assess the safety and effectiveness of a contact force sensing catheter used for ablation in patients with paroxysmal atrial fibrillation.
- Trial name
- TOCCASTAR (NCT01278953)
- Testing
- Catheter ablation to treat paroxysmal atrial fibrillation
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Abbott Medical Devices
Persistent Atrial Fibrillation, Persistent Atrial Fibrillation Longstanding
Catheter Ablation of Advanced Forms of Atrial Fibrillation
The purpose of this study is to evaluate feasibility, safety, and efficacy of pulmonary vein isolation combined with posterior left atrial isolation and multiple linear lesions in both atria in patients with persistent and…
- Trial name
- ENDO MAZE (NCT07446244)
- Testing
- Endovascular ablation set mimicking cox maze 4 procedure.
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Atrial Fibrillation, Catheter Ablation
Bladder Catheters During Ablation Procedures
Inserting a Bladder catheter during catheter ablation is standard practice at most Institutions. Unfortunately, bladder catheters are associated with adverse outcomes, including catheter associated cystitis, hematuria, dysuria…
- Conditions
- Atrial Fibrillation, Catheter Ablation, Catheter Complications
- Trial name
- NCT03635034
- Testing
- Insert bladder catheter, No catheter
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- St. Vincent Cardiovascular Research Institute
Atrial Fibrillation, Persistent, Heart Failure
Comparison of Catheter Plus Marshall Vein Ablation vs. Catheter Ablation Alone in Persistent AF With Heart Failure
This multicenter, randomized controlled trial aims to compare the clinical efficacy and safety of combining catheter ablation with Marshall vein ethanol ablation versus catheter ablation alone in patients with persistent atrial…
- Trial name
- NCT06578793
- Testing
- Catheter Ablation Combined with Marshall Vein Ethanol Ablation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Xiangya Hospital of Central South University
Atrial Fibrillation
NURSE-led Follow-up in Patients Undergoing CATheter Ablation for Atrial Fibrillation
The study aims to examine the effect of nurse-led education program on quality of life, atrial fibrillation (AF) risk factors, AF symptomatology, arrhythmia recurrence rate, and readmission rate after AF catheter ablation.
- Trial name
- NURSECAT-AF (NCT05333445)
- Testing
- educational program, risk factors management, telephone and e-mail contact
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Hospital Clinic of Barcelona
BTKi-induced Atrial Fibrillation, Hematologic Malignancy
IRAF-ABLATION Study: a Multicenter International Retrospective Cohort of Patients With BTK Inhibitors-related AF Treated by Catheter Ablation
Targeted anticancer drugs have completely changed the prognosis of malignancies during the past decades. Patients suffering from malignancies live longer and this allows adverse events of anticancer drugs to emerge, notably…
- Conditions
- BTKi-induced Atrial Fibrillation, Hematologic Malignancy, Atrial Fibrillation Catheter Ablation
- Trial name
- NCT06130709
- Testing
- Atrial fibrillation catheter ablation in a population of BTKi-induced atrial fibrillation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Atrial Fibrillation
Exhaustive French National Registry of AF Ablation Using Pentaspline Pulsed Field Ablation Catheter
Pulsed field ablation (PFA) is a nonthermal ablative modality using a strong electrical field created around a dedicated catheter to produce pores in the cellular membrane.
- Trial name
- FRANCE-PFA (NCT06497933)
- Testing
- Atrial fibrillation ablation
- Where
- France
- Volunteers
- 5,223 people
- Sponsor
- University Hospital, Rouen
Atrial Fibrillation, Ischemic Ventricular Tachycardia
Study of a New Catheter Using Force Sensing Capabilities for the Treatment of Atrial Fibrillation and Ventricular Tachycardia
The purpose of this study is to study the treatment of Atrial Fibrillation and ischemic Ventricular Tachycardia using a RF ablation catheter with contact force sensing capabilities.
- Trial name
- EZCF-125 (NCT01032317)
- Testing
- Radiofrequency Catheter Ablation
- Where
- Czechia
- Volunteers
- 22 people
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation
Risk of Asymptomatic Cerebral Embolism During AF Ablation With AI-HPSD Strategy Versus Standard Settings
The purpose of this prospective randomized controlled study is to evaluate the risk of asymptomatic cerebral embolism during catheter ablation of atrial fibrillation (AF) with AI-HPSD strategy versus standard radiofrequency…
- Trial name
- NCT04408716
- Testing
- Ablation Index Guided High-Power Short-Duration Strategy, Standard Radiofrequency Ablation Technique
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Atrial Fibrillation Paroxysmal
Clinical and Electrophysiological Predictors of Arrhythmic Recurrence in Patients With Paroxysmal AF Undergoing First Ablation Procedure of AF by Pulmonary Vein Isolation
From the literature, the success rate (i.e., absence of AF recurrence) of ablation in cases of paroxysmal AF at one year changes between 70 and 85 percent. This rate is considered suboptimal.
- Trial name
- PREDICTORS (NCT06085014)
- Testing
- Standard of care, Data collection
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Centro Cardiologico Monzino
Type 2 Diabetes Mellitus (T2DM), Atrial Fibrillation (AF)
Strict Weight Management Based on GLP-1 RA for Ablation Outcomes in Overweight or Obese Patients with T2DM and AF
Objective To compare, in patients with Type 2 Diabetes Mellitus (T2DM) and Atrial Fibrillation (AF) undergoing radiofrequency ablation (RFA), whether strict weight management and glycemic control based on Glucagon-like Peptide-1…
- Trial name
- NCT06660134
- Testing
- Glucagon-like peptide-1 receptor agonists (GLP 1 RA)
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation
Renal Denervation + PVI vs PVI Alone for Persistent AF
Pulmonary vein isolation (PVI) is the cornerstone of ablation for atrial fibrillation (AF). Increased cardiac sympathetic stimulation can facilitate AF and reduction can be accomplished by renal artery denervation (RDN).
- Trial name
- ERADICATE-AF (NCT05116384)
- Testing
- catheter ablation, renal artery denervation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Rochester
Paroxysmal Atrial Fibrillation
Catheter Ablation Using a Novel Navigation and Imaging System
The objective of the ENVIsIoN study is to collect data on the use of the VERAFEYE navigation and imaging system in patients indicated to undergo a catheter ablation procedure for the treatment of Paroxysmal Atrial Fibrillation…
- Trial name
- ENVIsIoN (NCT06895187)
- Testing
- VERAFEYE System
- Volunteers
- 100 people
- Sponsor
- LUMA Vision Ltd.