Clinical trials: Atrial Fibrillation and Flutter
Atrial Fibrillation, Atrial Flutter
EURopean Trial In Atrial Fibrillation(AF) or Flutter (AFL) Patients Receiving Dronedarone for the maIntenance of Sinus Rhythm (EURIDIS)
To assess the efficacy of dronedarone versus placebo for the maintenance of normal sinus rhythm after electrical, pharmacological or spontaneous conversion of atrial fibrillation/atrial flutter (AF/AFL).
- Trial name
- EURIDIS (NCT00259428)
- Testing
- Dronedarone (SR33589)
- Where
- 12 sites in Belgium, Czechia and 10 more
- Volunteers
- 615 people
- Sponsor
- Sanofi
Intracranial Hemorrhages, Intracranial Hemorrhage, Hypertensive
Start or STop Anticoagulants Randomised Trial (SoSTART)
Primary research question: For adults surviving spontaneous (non-traumatic) symptomatic intracranial haemorrhage with persistent/paroxysmal atrial fibrillation/flutter (AF), does starting full treatment dose oral anticoagulation…
- Conditions
- Intracranial Hemorrhages, Intracranial Hemorrhage, Hypertensive, Subarachnoid Hemorrhage, Subdural Hematoma
- Trial name
- SoSTART (NCT03153150)
- Testing
- Apixaban, Rivaroxaban, Edoxaban
- Where
- 67 sites in United Kingdom
- Volunteers
- 203 people
- Sponsor
- University of Edinburgh
Heart Failure, Tachycardia
Safety and Efficacy Study of RENEWAL 4 AVT
The purpose of this study is to assess the safety and effectiveness of the CONTAK RENEWAL 4 AVT device.
- Conditions
- Heart Failure, Tachycardia, Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT00180336
- Testing
- CRT-D
- Where
- Germany
- Volunteers
- 170 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation, Atrial Flutter
Comparison of Intracardiac Echocardiography and Transesophageal Echocardiography
The presence of intracardiac thrombi and their propensity for systemic embolism is a major concern in patients with atrial fibrillation (AF) and atrial flutter (AFL) undergoing cardioversion and ablation procedures.
- Trial name
- ICE-TEE (NCT02213666)
- Testing
- Intracardiac Imaging
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Elad Anter
Atrial Fibrillation, Atrial Flutter
Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects
The purpose of this study is to demonstrate the ability of tedisamil to convert atrial fibrillation or flutter into normal sinus rhythm (NSR) in female patients.
- Trial name
- NCT00126022
- Testing
- Tedisamil sesquifumarate
- Where
- 81 sites in United States, Argentina and 11 more
- Sponsor
- Solvay Pharmaceuticals
Atrial Fibrillation, Atrial Flutter
Sodium Channel Splicing in Heart Failure Trial
The purpose of this research is to see if investigators can detect truncated mRNA splice variants of the cardiac voltage-gated sodium (Na+) channel gene, SCN5A, in patients with a weak heart (Heart Failure) with or without an…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Heart Failure
- Trial name
- SOCS-HEFT (NCT01185587)
- Where
- 2 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Atrial Fibrillation, Atrial Flutter
Prevalence of Primary Aldosteronism in Hypertensive Patients Presenting With Atrial Flutter or Fibrillation
Primary objective of the PAPPHY Study is to establish the prevalence of primary aldosteronism (PA) in consecutive hypertensive patients referred for 'lone' paroxysmal, persistent or permanent atrial flutter or fibrillation (AFF).
- Conditions
- Atrial Fibrillation, Atrial Flutter, Aldosteronism
- Trial name
- PAPPHY (NCT01267747)
- Where
- 2 sites in Italy
- Volunteers
- 411 people
- Sponsor
- University Hospital Padova
Atrial Fibrillation/Flutter in Patients With High Risk of Stroke
A Clinical Trial to Evaluate the Detection of Atrial Fibrillation for an One Day Versus More Than or Equal to Eight Days Using MEMO Patch PLUS in Individuals Aged ≥ 75 Years, or Those at High Risk of Stroke
The purpose of this study is to evaluate the benefits in the atrial fibrillation detection rate of the continuous ECG monitoring group for more than 8 days by contrasting with one-day ECG monitoring using MEMO Patch PLUS in 1000…
- Trial name
- MEMO-DAF8 (NCT05355948)
- Testing
- MEMO Patch PLUS for 1 day, MEMO Patch PLUS for More than 8-days
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Yonsei University
Intensive Care Unit, Coronary Artery Bypass Grafting (CABG)
Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients
The MODIFY CSX study is a prospective, randomized, placebo-controlled trial conducted in heart centers in Germany and Italy. A total of 550 high-risk cardiac surgery patients will receive either 0.20 g fish oil/kg body weight…
- Conditions
- Intensive Care Unit, Coronary Artery Bypass Grafting (CABG), High Risk Patients, Cardiopulmonary Bypass
- Trial name
- MODIFY CSX (NCT06279793)
- Testing
- Fish Oil, Intravenous 0.9% Sodium Chloride
- Where
- 10 sites in Germany
- Volunteers
- 550 people
- Sponsor
- GCP-Service International West GmbH
Atrial Fibrillation, Atrial Arrhythmia
Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The study aims to evaluate and compare the incidence of atrial arrhythmias (including Post-Operative Atrial Fibrillation (POAF), atrial flutter, and atrial tachycardia) stratified by baseline Utah fibrosis stages and overall…
- Conditions
- Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
- Trial name
- NCT05014802
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Atrial Fibrillation, Atrial Flutter
Prague Registry of Electric Cardioversion
This single-center observational registry follows contemporary efficacy and short-term complications of elective electric cardioversion.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia, Atrial Tachycardia
- Trial name
- PRAGUE-ECV (NCT04919902)
- Testing
- Electric cardioversion
- Where
- Czechia
- Volunteers
- 5,000 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Atrial Fibrillation, Atrial Flutter
Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Male Subjects
The purpose of this study is to demonstrate the ability of tedisamil to convert atrial fibrillation or flutter into normal sinus rhythm (NSR) in male patients.
- Trial name
- NCT00126061
- Testing
- Tedisamil sesquifumarate
- Where
- 26 sites in United States, Czechia and 3 more
- Sponsor
- Solvay Pharmaceuticals
Acute Coronary Syndrome, Myocardial Infarction
What is the Optimal Antithrombotic Strategy in Patients With Atrial Fibrillation Undergoing PCI?
The optimal antithrombotic management in patients with coronary artery disease (CAD) and concomitant atrial fibrillation (AF) is unknown.
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Atrial Fibrillation, Atrial Flutter
- Trial name
- WOEST-3 (NCT04436978)
- Testing
- 30-day DAPT, Guideline-directed therapy
- Where
- 20 sites in Belgium, Netherlands
- Volunteers
- 2,000 people
- Sponsor
- St. Antonius Hospital
Atrial Fibrillation and Flutter
Oral vs Intravenous Diltiazem for Rapid Atrial Fibrillation/Flutter Trial
The primary objective of this study is to compare the incidence of rate control (defined as: HR <110 beats/min or conversion to sinus rhythm) at 2 hours after medication administration between oral immediate release diltiazem and…
- Trial name
- OVID RAF (NCT03472495)
- Testing
- Diltiazem Oral Product, Diltiazem Injectable Product
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Virginia Commonwealth University
Atrial Fibrillation, Atrial Flutter
Left Atrial Thrombus on Transesophageal Echocardiography
The aim of the study is to assess the prevalence of left atrial thrombus in patients with atrial fibrillation (AF) or atrial flutter (AFI), in whom transesophageal echocardiography is performed before AF/AFl cardioversion or…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Transesophageal Echocardiography, Ablation
- Trial name
- LATTEE (NCT03591627)
- Testing
- Transesophageal echocardiography
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Warsaw
Atrial Fibrillation, Atrial Flutter
Prevention of Atrial Fibrillation by Inhibition Conversion Enzyme (ICE) After Radiofrequency Ablation of Atrial Flutter
Atrial Flutter [AFL] is a relatively frequent arrhythmia, considered as benign, but associated with both invalidating symptoms and thromboembolic risk.
- Trial name
- PREFACE (NCT00736294)
- Testing
- Ramipril
- Where
- 8 sites in France
- Volunteers
- 198 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Atrial Fibrillation
A Retrospective Study of the Role of Thiazolidinediones to Reduce the Incidence of Atrial Arrhythmias
It is well known that abnormal heart beats from the top parts of the heart, atrial fibrillation (AF) and atrial flutter (Aflut), occur frequently after most types of cardiac surgeries.
- Trial name
- NCT00321204
- Testing
- TZD reducing the incidence of atrial arrhythmias
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Emory University
Arrhythmias, Cardiac, Atrial Fibrillation
enHEART - Exploring Full Content of Optical Signals to Enhance Cardiac Arrhythmia Screening
This research will investigate the PPG signal morphology related to physiological and non- physiological changes in arrhythmia-related heart rate as well as the performance of the PPG-based features previously developed within…
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Atrial Flutter, Atrioventricular Block
- Trial name
- enHEART (NCT04884100)
- Testing
- Validating and improving PPG-based algorithms
- Where
- Switzerland
- Volunteers
- 95 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Fibrosis, Atrial Fibrillation
Myocardial Fibrosis in Patients With Permanent Pacemakers
Patients with cardiac pathology and arrhythmias including those who have indications for pacemakers implantation will be included in the study.
- Conditions
- Fibrosis, Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT05920226
- Testing
- pacemakers implantation and assessment of cardiac function and cardiac fibrosis, assessment of cardiac function and cardiac fibrosis
- Where
- Russia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ryazan State Medical University
Atrial Fibrillation and Flutter
Risk-Based Screening for the Evaluation of Atrial Fibrillation Trial
1. To determine whether a risk-based screening programme for occult paroxysmal atrial fibrillation, involving extended cardiac monitoring in adults with CHA2DS2-VASc score of 3 or greater, increases the detection of new atrial…
- Trial name
- R-BEAT (NCT03911986)
- Testing
- R Test 4 External Loop Recorder
- Where
- Ireland
- Volunteers
- 755 people
- Sponsor
- National University of Ireland, Galway, Ireland