Clinical trials: Atrophic Acne Scarring
Acne Scars - Mixed Atrophic and Hypertrophic, Acne
Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring
This single-center, clinical trial consists of a one autologous fat grafting treatment followed by 3-month and 6-month post-treatment visits in order to assess the efficacy of fat grafting when used by men and women with facial…
- Trial name
- NCT04559022
- Testing
- Fat Grafting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Acne Scars
Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars
The purpose of this study is to compare two treatments for acne scars on the face. The study will test whether fractional lasers (Erbium:Glass and Thulium) lead to better improvement in acne scars than microneedling.
- Trial name
- NCT07151599
- Testing
- Microneedling, Fractionated Er:Glass Laser combined to Fractionated Thulium Laser
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- University of Nove de Julho
Acne Vulgaris
Study of Trifarotene Cream to Assess Risk of a Trophic Acne Scar Formation
The purpose of this study is to evaluate the safety and efficacy of trifarotene 50 microgram per gram (mcg/g) cream compared to its vehicle on the risk of formation of atrophic acne scars after 24 weeks of treatment in facial…
- Trial name
- START (NCT04856904)
- Testing
- Trifarotene Cream, Trifarotene Vehicle Cream
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 121 people
- Sponsor
- Galderma R&D
Acne Scars, Atrophic Acne Scars
Ultherapy® for the Treatment of Acne Scars
This is a prospective, multi-site trial to be conducted at 2 clinical sites. Up to 20 subjects will receive study treatments. Following study treatments, follow-up visits will occur at 60, 90 and 180 days from each subject's last…
- Trial name
- NCT02145364
- Testing
- Ultherapy® treatment
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Ulthera, Inc
Acne Scars
Adapalene Gel 0.3% in the Treatment of Atrophic Acne Scars
The purpose of this study is to assess the efficacy and safety of Adapalene Gel 0.3% in the treatment of atrophic acne scars.
- Trial name
- NCT01213199
- Testing
- Adapalene
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Treatment of Acne Scars With Erbium:Yttrium Aluminum Garnet (Er:YAG) Laser Examined Under OCT
This study is examining the effects of the 2940 nm Er:YAG on atrophic facial acne scars under optical coherence tomography in terms of blood flow, vessel shape, skin roughness, collagen content, and epidermal thickness.
- Trial name
- NCT03333759
- Testing
- Alma - Harmony XL Laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Atrophic Acne Scar
A Study to Evaluate the Efficacy of ELAPR002f in Females and Males With Atrophic Acne Scars
The study is designed to evaluate the efficacy of two formulations of a cross-linked tropoelastin matrix given the product codes ELAPR002f (collectively referred to as ELAPR or ELAPR002) for the treatment of rolling atrophic acne…
- Trial name
- NCT03056235
- Testing
- ELAPR002f, Saline
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Elastagen Pty Ltd
Atrophic Acne Scar
Fractional CO₂ Laser Combined With Topical Plant-Derived Exosomes Versus Non-Cross-Linked Hyaluronic Acid for Atrophic Acne Scars
Fractional CO₂ laser combined with topical exosomes and non-cross-linked hyaluronic acid both improve atrophic acne scars, but direct comparative evidence between these adjunctive therapies has been limited.
- Trial name
- NCT07868445
- Testing
- Fractional co2 laser, Exosomes, Hyaluronic Acid skin booster
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Atrophic Acne Scar
Fractional CO2 Laser Combined With PRP Fluid Versus Gel in Treatment of Acne Scars
This study is to test the efficacy of fractional laser combined with either PRP fluid or PRP gel in the treatment of atrophic acne scars
- Trial name
- PRP (NCT04580758)
- Testing
- Fractional laser with PRP fluid or PRP gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Yasmine Ahmed Abd El-Maguid El-Hadidy
Acne Atrophica, PRP
Poly-L-Lactic Acid Threads Versus Platelet-Rich Plasma for Post-Traumatic Atrophic Scars
This study compares the efficacy and safety of poly-L-lactic acid (PLLA) threads versus platelet-rich plasma (PRP), both combined with subcision, in the treatment of post-traumatic atrophic scars.
- Trial name
- PLLA-PRP PTAS (NCT07775092)
- Testing
- subcision and PLLA threads' insertion, PRP and subcision (PRP-S)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Tanta University
Atrophic Acne Scars
Efficacy of Human UC-MSC-derived Exosomes and BM-MSC-derived Exosomes for Atrophic Acne Scar
The goal of this clinical trial is to learn if exosomes from human umbilical cord and bone marrow can improve atrophic acne scars when used after fractional CO₂ laser treatment in adults.
- Trial name
- NCT07510295
- Testing
- Exosomes derived from human umbilical cord and bone marrow mesenchymal stem cells, Hyaluronic Acid (HA)
- Where
- Vietnam
- Volunteers
- 22 people
- Sponsor
- Ngô Anh Tuấn
Atrophic Acne Scar
Clinical Application of Patented Lyophilized PLT in Acne Scar Repairment.
All kinds of skin problems will cause a person's life caused by varying degrees of trouble, especially issues at face. No matter diseases or aging would cause mental pressure and the inconvenience in different ages.
- Trial name
- NCT04829370
- Testing
- PLT, Saline
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Atrophic Acne Scar
Phenytoin in Treatment of Atrophic Post Acne Scars.
To evaluate the efficacy and safety of topical phenytoin spanlastics as an adjuvant therapy in treatment of atrophic post acne scars.
- Trial name
- NCT06942468
- Testing
- Topical nano preparation of Phenytoin, Fractional CO2 laser
- Volunteers
- 30 people
- Sponsor
- Assiut University
Acne Scar, Acne Scars - Atrophic
Efficacy and Safety of a 1064-nm Nd:YAG Picosecond Laser Versus a 1927-nm Fractional Laser for Atrophic Acne Scars.
Atrophic acne scars are common disfiguring skin problems, especially in the Asian population prone to Post-inflammatory Hyperpigmentation (PIH), and their treatment is highly challenging.
- Trial name
- NCT07153679
- Testing
- 1064-nm Nd:YAG Picosecond Laser, 1927-nm Fractional Thulium Laser
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Acne Vulgaris, Scar
Acne Scarring in Skin of Color: Laser vs Microneedling
Atrophic acne scars are a common and important sequelae of acne that affect up to 43-55% of patients with acne. Scarring impacts quality of life with reports of diminished self-esteem and frustration/sadness; additionally, some…
- Trial name
- NCT03395678
- Testing
- Microneedling, Fractional non-ablative 1,540nm laser
- Where
- United States
- Sponsor
- Boston University
Atrophic Acne Scar
Combined Therapy for Acne Scars
Compare the effectiveness of nonablative fractional resurfacing to radiofrequency micrnoeedling for facial acne scars in all skin types
- Trial name
- NCT05105334
- Testing
- Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alone, Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alternating with microneedling with radiofrequency (Intracel, Perigee Medical, Redwood City, CA)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars
Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face
Acne scars represent a frequent complication of moderate/severe acne and may negatively impact on psychosocial and physical well-being of acne patients.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars, Rolling Scars, Boxcar Scars
- Trial name
- NCT05691049
- Testing
- HCC_45
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Acne Scars - Mixed Atrophic and Hypertrophic
Microneedling With Topical Preparations in the Treatment of Atrophic Post-acne Scars
To examine the anti-scarring effect of topical glycolic acid 35% combined with microneedling against that of topical insulin combined with microneedling for post acne scars
- Trial name
- NCT05600075
- Testing
- microneedling with topical glycolic acid 35%., microneedling with topical human insulin solution.
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Wrinkle, Acne Scars - Mixed Atrophic and Hypertrophic
Functional Usability and Feasibility Testing of the Profound Matrix™ System
This is a non-randomized, multi-center, open-label clinical trial evaluating the efficacy and clinical feasibility of the Profound Matrix device for electrocoagulation and for treatment of wrinkles and acne scars.
- Trial name
- NCT06192550
- Testing
- Profound Matrix™ System
- Where
- 5 sites in United States, Israel
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Atrophic Acne Scars
Comparison of Efficacy of Carbon Dioxide Laser With Subcision Versus Platelet-Rich Plasma Bio-Fillers With Subcision for the Treatment of Atrophic Acne
This randomized controlled trial compared two combined treatment approaches for atrophic acne scars. A total of 100 patients aged 15-45 years were enrolled from the Department of Dermatology, Lahore General Hospital, Lahore, and…
- Trial name
- NCT07752186
- Testing
- Platelet-Rich Plasma Bio-Filler With Subcision, Fractional Carbon Dioxide Laser With Subcision
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Lahore General Hospital