Clinical trials: Atrophic Scar
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Atrophic Acne Scar
SkinPen Efficacy on Acne Scars on the Face and/or Back
This single-center, clinical trial will take place over a 90 day course followed by 1-month and 6-month post treatment visits to assess the efficacy and tolerability of the SkinPen device when used on both men and women on the…
- Trial name
- NCT02646917
- Testing
- Aesthetic Microneedling Treatment
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Atrophic Scar
Safety and Tolerability of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and tolerability for 12 weeks after one dose of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT06210919
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- CellinCells
Atrophic Acne Scars
Treatment of Atrophic Post Acne Scars by Fat Grafting
This single-center, clinical trial consists of a one autologous fat grafting treatment followed by1-week , 1month , 3-month and 6-month post-treatment visits in order to assess the efficacy and complications of fat grafting when…
- Trial name
- NCT05028283
- Testing
- Fat Grafting
- Where
- Syria
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Damascus University
Atrophic Scar
Vollure for the Correction of Atrophic Facial Scarring
Subjects will be randomized to receive up to 1cc of Juvéderm Vollure on one side of their face and up to 1cc of Saline on the other. On Day 30, this treatment with the same left-right assignment can be repeated.
- Trial name
- JVAS (NCT04519515)
- Testing
- Allergan Vollure
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Siperstein Dermatology
Acne Scars - Atrophic
Stromal Vascular Fraction Enriched PRP in Treatment of Post-acne Scars
in a split face fashion, 30 patients will be randomized into 3 groups: Group A: rt side treated with SVF enriched PRP, lt side treated with prp Group B: rt side treated with SVF enriched PRP, lt side treated with SVF Group C: rt…
- Trial name
- NCT06524011
- Testing
- Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Atrophic Scar
Role of Stem Cells, Platelet Rich Plasma in Treatment of Scars
The Objectives of this randomized controlled trial aiming to establishing a protocol of post scar revision care and to Study the effect of PRP and/or Adipose derived Mesenchymal Stem cell injection in improvement of atrophic scar…
- Trial name
- NCT03264573
- Testing
- Stem cell, MSCs
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Heba Mohamed Saad Eldien
Acne Vulgaris
Treatment of Acne Scars With Erbium:Yttrium Aluminum Garnet (Er:YAG) Laser Examined Under OCT
This study is examining the effects of the 2940 nm Er:YAG on atrophic facial acne scars under optical coherence tomography in terms of blood flow, vessel shape, skin roughness, collagen content, and epidermal thickness.
- Trial name
- NCT03333759
- Testing
- Alma - Harmony XL Laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Acne Scars - Mixed Atrophic and Hypertrophic
Safety and Efficacy of Sofwave Treatment for Acne Scars Appearance Improvement
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT05358860
- Testing
- Sofwave
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Acne Scars - Mixed Atrophic and Hypertrophic
Treatment of Acne Scars With Fractional CO2 Laser Versus Radio-frequency Microneedling
The study is a prospective, randomized, controlled, intra-person split-face trial with blinded evaluations. The objective is to compare efficacy and adverse effects of ablative fractional CO2 laser resurfacing versus…
- Trial name
- NCT04252352
- Testing
- Ablative fractional CO2 laser resurfacing/Radio-frequency microneedling
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Atrophic Acne Scar
Evaluation of the Efficacy and Safety of Microneedling Combined With Botulinum Toxin-A Versus Meso-Botox Injection in the Treatment of Atrophic Acne Scars: A Split-face Comparative Study
Post-acne scars are psychologically disappointing and therapeutically challenging condition. No standard treatment for atrophic acne scars. Micro-Botox, is a highly diluted BTX-A which could be injected safely intra-dermally.
- Trial name
- NCT06544993
- Testing
- Meso-botox
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars
Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face
Acne scars represent a frequent complication of moderate/severe acne and may negatively impact on psychosocial and physical well-being of acne patients.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars, Rolling Scars, Boxcar Scars
- Trial name
- NCT05691049
- Testing
- HCC_45
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Atrophic Acne Scar
A Study to Evaluate the Efficacy of ELAPR002f in Females and Males With Atrophic Acne Scars
The study is designed to evaluate the efficacy of two formulations of a cross-linked tropoelastin matrix given the product codes ELAPR002f (collectively referred to as ELAPR or ELAPR002) for the treatment of rolling atrophic acne…
- Trial name
- NCT03056235
- Testing
- ELAPR002f, Saline
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Elastagen Pty Ltd
Atrophic Acne Scar
Combined LASERs and PRP for Postacne Scars
This study evaluates a new combined technique using two different laser wavelengths and Platelets Rich Plasma (PRP) to treat post-atrophic acne scars.
- Trial name
- NCT03809416
- Testing
- Lasers, Platelets Rich Plasma, Lasers plus Normal Saline Solution
- Where
- 2 sites in Italy, Kuwait
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- DEKA S.r.l.
Acne Scars
Lasers to Aid in Treatment of Acne Scars
To assess efficacy and safety of paired picosecond 755nm Alexandrite laser with focused lens array (PSAL; Picosure®, Cynosure, Westford, MA) and radiofrequency microneedling (RFM; Potenza™, Cynosure, Westford, MA) for treatment…
- Trial name
- NCT05579171
- Testing
- Picosecond 755nm Alexandrite Laser
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Acne Scar
Comparing the Efficacy of Topical Tazarotene Gel 0.1% v/s Microneedling in Atrophic Post Acne Scars
The purpose of this study was to compare the Efficacy of Topical Tazarotene gel 0.1% versus Microneedling in atrophic Post acne scars.
- Trial name
- NCT05573425
- Testing
- Tazarotene gel 0.1%, Microneedling
- Where
- Pakistan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Atrophic Acne Scar
Combined Therapy for Acne Scars
Compare the effectiveness of nonablative fractional resurfacing to radiofrequency micrnoeedling for facial acne scars in all skin types
- Trial name
- NCT05105334
- Testing
- Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alone, Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alternating with microneedling with radiofrequency (Intracel, Perigee Medical, Redwood City, CA)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Acne Scars
Comparison of 1,550-nm Laser and Fractional Radiofrequency Microneedle for the Treatment of Acne Scars in Ethnic Skin
The primary objective of this randomized, split-face, controlled study is to compare the efficacy and safety of a erbium-doped 1,550-nm non-ablative fractional laser and a bipolar fractional radiofrequency microneedle device for…
- Trial name
- NCT03380845
- Testing
- Fraxel Restore, Fractora
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation
Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color
The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative/ablative laser for acne scarring in skin of color.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation, Laser-Induced Hyperpigmentation
- Trial name
- NCT05362929
- Testing
- Sciton Halo
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Wrinkle, Acne Scars - Mixed Atrophic and Hypertrophic
Functional Usability and Feasibility Testing of the Profound Matrix™ System
This is a non-randomized, multi-center, open-label clinical trial evaluating the efficacy and clinical feasibility of the Profound Matrix device for electrocoagulation and for treatment of wrinkles and acne scars.
- Trial name
- NCT06192550
- Testing
- Profound Matrix™ System
- Where
- 5 sites in United States, Israel
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Candela Corporation