Clinical trials: Atrophic Scar
Acne Scar
Comparing the Efficacy of Topical Tazarotene Gel 0.1% v/s Microneedling in Atrophic Post Acne Scars
The purpose of this study was to compare the Efficacy of Topical Tazarotene gel 0.1% versus Microneedling in atrophic Post acne scars.
- Trial name
- NCT05573425
- Testing
- Tazarotene gel 0.1%, Microneedling
- Where
- Pakistan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Acne Scars - Mixed Atrophic and Hypertrophic
enLighten Laser With MLA Handpiece for Treatment of Moderate and Severe Acne Scars
The purpose of this pivotal investigation is to evaluate the efficacy and safety of the Cutera enlighten multi-wavelength 532 nm and 1064 nm Nd:YAG picosecond pulse duration laser and an investigational micro-lens array (MLA)…
- Trial name
- NCT03284333
- Testing
- other
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Acne Scars - Mixed Atrophic and Hypertrophic
Comparison of 1,550 and 755 Laser in a Split-face Trial
Clinical Trial comparing the 1,550-nanometer fractionated photothermolysis system laser to the 755 nanometer picosecond laser using a split-face (Right-Left) comparison.
- Trial name
- NCT03988049
- Testing
- 1,550 fracionated photothermolysis laser, 755 picosecond laser
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- David Smart
Acne Scars
Lasers to Aid in Treatment of Acne Scars
To assess efficacy and safety of paired picosecond 755nm Alexandrite laser with focused lens array (PSAL; Picosure®, Cynosure, Westford, MA) and radiofrequency microneedling (RFM; Potenza™, Cynosure, Westford, MA) for treatment…
- Trial name
- NCT05579171
- Testing
- Picosecond 755nm Alexandrite Laser
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Acne Atrophica, PRP
Poly-L-Lactic Acid Threads Versus Platelet-Rich Plasma for Post-Traumatic Atrophic Scars
This study compares the efficacy and safety of poly-L-lactic acid (PLLA) threads versus platelet-rich plasma (PRP), both combined with subcision, in the treatment of post-traumatic atrophic scars.
- Trial name
- PLLA-PRP PTAS (NCT07775092)
- Testing
- subcision and PLLA threads' insertion, PRP and subcision (PRP-S)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Tanta University
Atrophic Acne Scars
ELAPR002f Injectable Gel in the Treatment of Atrophic Acne Scars
Visit the study website https://dawnacnescarstudy.com/ACT for more information. Atrophic acne scars are flat, indented or with an inverted center scars that develop at the endpoint of the normal healing process for acne.
- Trial name
- NCT05995340
- Testing
- ELAPR002f Injectable Gel, Saline Active Control
- Where
- 12 sites in Canada, Germany
- Volunteers
- 157 people
- Sponsor
- AbbVie
Atrophic Acne Scars, Acne Vulgaris
Microneedling With Glycolic Acid or Trichloroacetic Acid for Atrophic Acne Scars
Atrophic acne scars are depressed scars that can remain after acne has healed. Microneedling is a procedure that uses very small needles to create controlled micro-injuries in the skin, which may stimulate collagen production and…
- Trial name
- NCT07797517
- Testing
- Microneedling only, Microneedling with Glycolic Acid 35% Peel, Microneedling with Trichloroacetic Acid 15% Peel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Acne Scars - Mixed Atrophic and Hypertrophic, Scar
Impact of Tripolar Radiofrequency on Acne Scar
The aim of this study is to investigate the therapeutic efficacy of tripolar radiofrequency on acne scar
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Scar, Radiofrequency
- Trial name
- NCT06492356
- Testing
- Tripolar radiofrequency therapy, medical treatment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Laser-Induced Scar, Breast Cancer
Laser Treatment of Genito-urinary Syndrome in Women
Women with genitourinary syndrome of menopause, overactive bladder, with breast or endometrial cancer are randomized to either laser treatment og sham treatment for 3 months.
- Conditions
- Laser-Induced Scar, Breast Cancer, Endometrial Cancer, Menopause
- Trial name
- NCT03238053
- Testing
- Vaginal laser treatment, laser system
- Where
- Denmark
- Sponsor
- Herning Hospital
Atrophic Acne Scar
Fractional CO₂ Laser Combined With Topical Plant-Derived Exosomes Versus Non-Cross-Linked Hyaluronic Acid for Atrophic Acne Scars
Fractional CO₂ laser combined with topical exosomes and non-cross-linked hyaluronic acid both improve atrophic acne scars, but direct comparative evidence between these adjunctive therapies has been limited.
- Trial name
- NCT07868445
- Testing
- Fractional co2 laser, Exosomes, Hyaluronic Acid skin booster
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Post-acne Atrophic Scars
Comparison of Efficacy of Microneedling With Platelet Rich Plasma Vs Microneedling With Topical Insulin in the Treatment of Acne Scars
This study compares the outcome of two procedures for the treatment of atrophic acne scars.
- Trial name
- NCT06978361
- Testing
- Microneedling with autologous Platelet Rich Plasma, Microneedling with topical insulin
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Khyber Teaching Hospital
Acne Scars - Atrophic
Nano Fat Injection With or Without Fractional Carbon Dioxide Laser in Acne Scars
Assessment of nano fat grafting combined with carbon dioxide laser resurfacing versus nano fat grafting alone in treating facial atrophic acne scars
- Trial name
- NCT05985265
- Testing
- Fat grafting
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Acne Scars, Atrophic Acne Scars
Ultherapy® for the Treatment of Acne Scars
This is a prospective, multi-site trial to be conducted at 2 clinical sites. Up to 20 subjects will receive study treatments. Following study treatments, follow-up visits will occur at 60, 90 and 180 days from each subject's last…
- Trial name
- NCT02145364
- Testing
- Ultherapy® treatment
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Ulthera, Inc
Atrophic Scar
Vollure for the Correction of Atrophic Facial Scarring
Subjects will be randomized to receive up to 1cc of Juvéderm Vollure on one side of their face and up to 1cc of Saline on the other. On Day 30, this treatment with the same left-right assignment can be repeated.
- Trial name
- JVAS (NCT04519515)
- Testing
- Allergan Vollure
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Siperstein Dermatology
Scar; Atrophy
Cannula-based Versus Needle-based Subcision for Posttraumatic Atrophic Facial Scars
This study aims to evaluate the effectiveness of cannula- based subcision versus common needle subcision in treatment of posttraumatic atrophic facial scars
- Trial name
- NCT05747898
- Testing
- cannula- based subcision, common- needle based subcision
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Acne Scars - Mixed Atrophic and Hypertrophic
Clinical Evaluation of the Safety and Performance of FRF for the Treatment and Reduction of Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT04827680
- Testing
- Venus Viva MD
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Wrinkle, Acne Scars - Mixed Atrophic and Hypertrophic
AV-23-001 AVAVA MIRIA Pilot Study
This non-significant risk study is intended to demonstrate the use of the MIRIA Skin Treatment System can show improvement in dermatologic conditions currently indicated for treatment with a laser (such as, but not limited to…
- Conditions
- Wrinkle, Acne Scars - Mixed Atrophic and Hypertrophic, Pigmented Lesions, Skin Laxity
- Trial name
- NCT06557434
- Testing
- MIRIA
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AVAVA, Inc.
Wound Healing
Plasma Therapy for Scar Management
This study is a prospective, multicenter, real-world observational study. It aims to evaluate whether adding plasma device therapy to standard scar care is effective and safe for treating various types of scars, including…
- Trial name
- NCT07548593
- Testing
- Plasma Device
- Volunteers
- 800 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Atrophic Scar
Safety and Tolerability of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and tolerability for 12 weeks after one dose of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT06210919
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- CellinCells
Presbylarynx, Atrophy; Larynx
Serial Platelet-Rich Plasma Injections for Vocal Fold Atrophy, Scar, and/or Sulcus Vocalis
This study will investigate the safety and efficacy of four serial monthly vocal fold injections of platelet-rich plasma to treat dysphonia secondary to vocal fold atrophy, scar, and/or sulcus vocalis with glottal insufficiency
- Conditions
- Presbylarynx, Atrophy; Larynx, Dysphonia, Vocal Cord Atrophy
- Trial name
- NCT03749863
- Testing
- Serial PRP injections
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California