Clinical trials: Atrophy; Bone
Ridge Augmentation
Autogenous Bone Ring Versus Split Bone Block for Management of Posterior Atrophic Mandible
Teeth loss in the posterior mandible initiates residual ridge resorption especially in vertical direction, this causes difficulty in implant placement so ridge augmentation must be done either simultaneous with implant placement…
- Trial name
- NCT07140887
- Testing
- Bone Ring, Split Bone block
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Alveolar Bone Atrophy, Bone Resorption
Effect of Citric Acid Demineralization on Autogenous Bone Blocks Consolidation in Humans
This study evaluates the effect of citric acid demineralization in autogenous bone blocks consolidation. Half of participants will receive citric acid treatment at the bone block and recipient site.
- Trial name
- NCT03357068
- Testing
- Control, Acid
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo
Bone Loss, Alveolar
Evaluation of Vertical Bone Gain After Ridge Augmentation With APRF & Xenograft Vs Collagen Membrane & Xenograft. RCT
Comparative study for evaluation of vertical bone gain after one stage ridge augmentation with advanced platelet rich fibrin (A-PRF) and xenograft versus guided bone regeneration using collagen membrane and xenograft.
- Trial name
- NCT03855852
- Testing
- Xenograft and Collagen membrane, Xenograft and APRF
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Horizontal Ridge Deficiency
Assessment of GBR in Augmentation of Horizontally Atrophic Maxillary Ridge Using Collagen Membrane Versus Using Titanium Mesh
this study is aiming to Assess postoperative complications and bone quality and quantity in augmentation of horizontally atrophic maxillary ridge using a 1:1 mixture of autograft and xenograft particulate bone covered with…
- Trial name
- NCT03635658
- Testing
- titanium mesh, collagen membrane (Sausage technique)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
Comparison Synthetic Hydroxyapatite and Inorganic Bovine Bone in Sinus Floor Elevation
This is set as prospective clinical trial to correlate histologically and radiologically the performance of four different bone grafts (synthetic hydroxyapatite alone, synthetic hydroxyapatite mixed with polylactic-polyglycolic…
- Trial name
- SYNBIO (NCT03077867)
- Testing
- sinus floor augmentation with bone graft
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Mandibular Atrophy
Three-Dimensional Bone Augmentation of Severely Atrophied Posterior Mandibular Alveolar Ridges Using Customized-3D Zirconia Barriers Versus Pre-bent Titanium Mesh
Zirconia can be considered as an alternative and innovative material suitable for GBR because it has high biocompatibility, together with a scarce tissue integration.
- Trial name
- NCT07700095
- Testing
- customized Zirconia barrier, prebent titanium mesh
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Hams Hamed Abdelrahman
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dental Caries
Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites
The purpose of this study is to determine the difference in success when placing implants immediately into an extraction site compared to delaying the implant placement until the extraction site has healed.
- Trial name
- NCT00067392
- Testing
- Dental Implant
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Muscular Dystrophy, Duchenne Muscular Dystrophy
Study Safety and Efficacy of BMMNC for the Patient With Duchenne Muscular Dystrophy
This Study is single arm, single center trial to check the safety and efficacy of BMMNC (100 million per dose) for the patient with Duchenne Muscular Dystrophy,
- Trial name
- BMMNC (NCT01834040)
- Testing
- Intralesional/ Intravenous of Autologous Stem cells.
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chaitanya Hospital, Pune
Sarcopenia, Osteoporosis
The Effect of Bovine Colostrum Supplementation in Older Adults
Bovine colostrum is the initial milk secreted by cows during the first day after calving. Colostrum is high in protein and contains a number of substances that have potential to be beneficial for the immune system.
- Trial name
- NCT01792297
- Testing
- Bovine colostrum, Whey protein
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Alveolar Bone Resorption
Trans-gingival or Subcrestal Short Implants Posterior Maxilla Bone Changes
two groups of inserted implants: trans-gingival and under-bone level; difference in the marginal bone loss at six months from placement between the two groups of implant positioned in the posterior atrophic maxilla
- Trial name
- NCT05975138
- Testing
- implant insertion
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- International Piezosurgery Academy
Osteoporosis, Sarcopenia
Skeletal Maturation and Endocrine Health in Young Adults
Diseases which can be the result of poor lifestyle choices in adult life, such as osteoporosis, obesity or poor muscle mass (sarcopenia) can also be driven by heritable genetic factors.
- Conditions
- Osteoporosis, Sarcopenia, Obesity, Cardiovascular Diseases
- Trial name
- EPIPEAK (NCT06509776)
- Where
- 9 sites in Denmark
- Volunteers
- 2,000 people
- Sponsor
- Holbaek Sygehus
Patients with Posterior Maxillary Atrophy and Need for Sinus Lift Surgery to Allow Implant Placement
Efficacy of L-PRF Against Deproteinized Bovine Mineralized Bone (DBBM)
Objective: The main objective of this study is to evaluate whether the use of L-PRF combined with deproteinized bovine mineralized bone (DBBM; BioOss, Geistlich Pharma®) reduces healing time, through histomorphometric analysis…
- Trial name
- NCT06686836
- Testing
- Sinus lift augmentation with bone substitute (Bio-Oss), Open sinus lift surgery lift using Platelet- and leukocyte-rich fibrin (L-PRF) mixed with a bone substitute (Bio-Oss®(Geistlich AG, Wolhusen, Switzerland)) - L-PRF Block
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Endosseous Dental Implant Failure, Alveolar Bone Loss
Plasma of Argon Cleaning on Implant Abutments: 5-year Results of a Randomized Clinical Trial
Contamination of implant abutments could potentially influence the peri-implant tissue inflammatory response. The aim of the present study was to assess the radiographic bone changes around customized, platform switched…
- Trial name
- NCT02552810
- Testing
- Steam clean, Plasma of Argon
- Volunteers
- 30 people
- Sponsor
- University of Valencia
Elderly, Metabolic Syndrome
Metabolic Syndrome and Vitamin D Level in Old People
In 2012, a cross-sectional survey sampling 1,966 community-dwelling old people was conducted. Structurized questionnaires were interviewed face-to-face by well-trained staffs.
- Conditions
- Elderly, Metabolic Syndrome, Vitamin D Deficiency, Ostreocalcin
- Trial name
- NCT03344718
- Where
- Taiwan
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Maxillary Sinus Disease, Alveolar Bone Loss
Crestal Sinus Lifting in Periodontally-Compromised Patients Utilizing Autologous Dentin Graft
The integration of artificial intelligence and computer-guided technology offers the potential for improving surgical accuracy, reducing complications, and enhancing outcomes.
- Trial name
- NCT06887582
- Testing
- Free-hand sinus lift augmanted by particulate autologous dentin graft + free-hand implant placement, AI-assisted/computer-guided sinus lift augmanted by particulate autologous dentin graft + computer-guided implant placement, Free-hand sinus lift with autologous dentin block graft +free-hand immediate implant placement
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Alveolar Bone Atrophy
Titanium Mesh vs Customized PEEK Mesh for Horizontal Maxillary Ridge Augmentation: A Randomized Clinical Trial
Background: Reconstruction of the deficient maxillary ridge in three dimensions is crucial for the successful placement of implants.
- Trial name
- NCT07002931
- Testing
- Prebent titanium mesh augmentation, Customized PEEK mesh augmentation
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Basma Alsheikh
Gingival Recession, Localized
Theravex Oral and Theravex Tissue Care Plus in the Healing Process of Mucogingival Surgery
This clinical study assesses the efficacy of two novel bioactive solutions, Theravex Oral and Theravex Tissue Care Plus, in enhancing soft tissue healing after periodontal surgery.
- Trial name
- NCT07430670
- Testing
- Modified Free Gingival Graft (M-FGG), Theravex Bioactive Solutions (Tissue Care Plus and Oral)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Bone Loss, Alveolar
Evaluation of Bone Gain Using Customized 3D Zirconia Barrier Versus Titanium Mesh
Evaluation of clinical and radiographical amount of bone gained using customized 3D printed zirconia barrier compared to titanium mesh in combined ridge defect at the esthetic zone.
- Trial name
- NCT06559605
- Testing
- zirconia barrier, titanium mesh
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Loss, Periodontal Bone Loss
Influence of the Implant Connection on Facial Tissues Maturation
The substitution of a tooth with a fixture often induces undesired morphological changes, resulting in a deterioration of the aesthetic appearance.
- Conditions
- Bone Loss, Periodontal Bone Loss, Implant Tissue Failure
- Trial name
- NCT04160689
- Testing
- implantology
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- University of Milan