Clinical trials: Attempted Suicide
Suicide, Attempted
Ketamine Treatment of Youth Suicide Attempters
Ketamine, an NMDA antagonist, has been shown to have rapid anti- suicidal effects. However, its safety and efficacy and special populations has not been investigated and documented.
- Trial name
- NCT04763343
- Testing
- Ketamine Hydrochloride, Saline, CAMS Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tatiana Falcone, MD
Suicide, Suicide, Attempted
Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care
This study is being completed to examine different combinations of technology-augmented strategies to identify an effective Adaptive intervention (AI) addressing post-discharge suicide risk with high implementation potential.
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation, Self Harm
- Trial name
- NCT05282225
- Testing
- MI- Safety Plan, Texts messages, Monitoring
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Michigan
Suicidal, Suicide, Attempted
Improving Coping to Reduce Suicide Risk Following ED Discharge
The researchers hope to learn whether an electronic safety plan (ESP) and a supportive text messaging program are feasible and acceptable to adult patients with recent suicidal thoughts or behavior after emergency department (ED)…
- Conditions
- Suicidal, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT06614946
- Testing
- Electronic Safety Plan (ESP), Text support
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Major Depressive Disorder, Suicidal Ideas
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
This study is dedicated to help identify biomarkers for depression and suicide. The purpose of the study is to better understand these links to improve medical and psychiatric care in the future.
- Conditions
- Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD
- Trial name
- NCT05437588
- Testing
- Genetic testing
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Suicidal Ideation, Suicide Attempt
A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among…
- Trial name
- NCT06686901
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Psychotic Disorders, Bipolar Disorders
A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness
Suicide is a major public health concern, particularly among Veterans with serious mental illness (SMI, i.e., psychotic disorders or bipolar disorders).
- Conditions
- Psychotic Disorders, Bipolar Disorders, Suicidal Ideation, Suicide, Attempted
- Trial name
- NCT05537376
- Testing
- SUicide Prevention by Peers Offering Recovery Tactics
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- VA Office of Research and Development
Suicide Attempt, Suicide Ideation
A One-Arm Open Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and preliminary efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors…
- Trial name
- NCT06967545
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Sleep Problem, Suicidal Ideation
Sleep Treatment for Teens
The purpose of this research study is to test a brief (6-session), empirically supported, and highly disseminable version of digital (i.e., smartphone or web-based) cognitive behavioral therapy for insomnia (dCBT-I), called…
- Conditions
- Sleep Problem, Suicidal Ideation, Suicide, Attempted
- Trial name
- NCT05397353
- Testing
- Sleepio (TM)
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Rutgers, The State University of New Jersey
Suicide, Attempted, Suicide Ideation
Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), a suicide-specific intervention that helps…
- Conditions
- Suicide, Attempted, Suicide Ideation, Suicide, Suicide Prevention
- Trial name
- NCT06151158
- Testing
- Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI)
- Where
- 6 sites in United States
- Volunteers
- 484 people
- Sponsor
- Johns Hopkins University
Self-injury, Suicide
Brief Admission by Self-referral for Individuals With Self-harm: Effects on Compulsory Care
Brief Admission by self-referral (BA) is a standardized treatment model, providing patient-controlled and person-centered care. It was developed to reduce self-harm and compulsory care by promoting autonomy.
- Conditions
- Self-injury, Suicide, Suicide, Attempted, Self-harm
- Trial name
- NCT06406972
- Testing
- Brief Admission by self-referral (BA)
- Where
- 4 sites in Sweden
- Volunteers
- 1,343 people
- Sponsor
- Region Skane
Suicide, Attempted
Study About Treatment After a Suicide Attempt
Effective, brief, low-cost interventions for individuals who attempt suicide are needed to save lives and achieve the goals of the National Strategy for Suicide Prevention.
- Trial name
- NCT03894462
- Testing
- Attempted Suicide Short Intervention Program, Zero Suicide Usual Care
- Where
- 3 sites in United States
- Volunteers
- 443 people
- Sponsor
- University of Rochester
PTSD, Suicidal Ideation
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD).
- Conditions
- PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
- Trial name
- NCT06285708
- Testing
- Prolonged exposure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Suicidal Ideation, Suicide Attempt
Recovery Through Inspiration, Support, and Empowerment
The goal of this pilot study is to test the effectiveness of a novel intervention for young adults (ages 18-27) with mental health conditions who have been released from an acute care psychiatric facility.
- Conditions
- Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
- Trial name
- RISE (NCT07051200)
- Testing
- Peer Support Services Recovery
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicide Risk
Telehealth to Improve Prevention of Suicide (TIPS)
The study will rigorously evaluate whether synchronous, within-visit telemental health evaluation and intervention services can successfully overcome poor access to behavioral health and substandard suicide-related care in…
- Trial name
- TIPS (NCT04800029)
- Testing
- TIPS Program, TIPS Program + ED-SAFE
- Where
- United States
- Volunteers
- 32,406 people
- Sponsor
- University of Massachusetts, Worcester
Suicide and Self-harm, Suicide
Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Randomized Trial
The primary aim of the present study is leverage existing infrastructure to develop novel technological features for a novel personalized smartphone intervention system, called the Mobile Application to Prevent Suicide (MAPS)…
- Conditions
- Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT05202756
- Testing
- Mobile Application to Prevent Suicide (MAPS), EMA Monitoring Only
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Butler Hospital
Suicide, Suicide, Attempted
Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors
The primary aim of this project are to evaluate a comprehensive, practice-ready, and deployment-focused strategy for improving the prediction and prevention of suicide attempts among a sample of 4,000 patients presenting to an ED…
- Trial name
- NCT05671133
- Testing
- Clinician Decision Support Tool
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation and Behaviors, Suicide Attempt
Video Conference-Based Brief Cognitive Behavioral Therapy for Suicidal High-Risk Outpatients With Mood Disorders
This pilot randomized controlled trial aims to evaluate the feasibility, acceptability, and preliminary effectiveness of videoconference-based brief cognitive behavioral therapy (V-BCBT) for adult outpatients with mood disorders…
- Conditions
- Suicidal Ideation and Behaviors, Suicide Attempt, Cognitive Behavioral Therapy
- Trial name
- V-BCBT (NCT07395817)
- Testing
- Videoconference-Based Brief Cognitive Behavioral Therapy (V-BCBT), Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Hyung Keun Park
Suicide, Attempted, Suicide Threat
Written Exposure Therapy for Suicide Prevention
Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period.
- Trial name
- NCT05878795
- Testing
- WET-SP, TAU
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Boston University
Relatives
Family Connections for Caregivers of People With Suicidal Behavior
The aim of our study is to verify the efficacy of the Family Connections intervention for relatives of people diagnosed with suicidal behavior disorder in a randomized control trial with a Spanish participants.
- Trial name
- NCT05157607
- Testing
- Family Connections Protocol for Relatives of Patients with SBD., Treatment as Usual Optimized Protocol (TAU-O)
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Suicide, Attempted
The Choice of a Violent Suicidal Means: a MRI Study With Computational Modeling of Decision-making
The study authors hypothesize a combination of cognitive, brain structural, brain functional and brain connectivity impairments in Suicide Attempters compared to Patient Controls and Healthy Controls, with deficits more marked in…
- Trial name
- SUICIDE_DECIDE (NCT05230043)
- Testing
- Algometer test, functional MRI
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes