Clinical trials: Attention-Deficit and Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder
Pharmacokinetic Study of Methylphenidate HCl Extended-Release Capsules in Children 4 to Under 6 Years of Age With ADHD
To assess the pharmacokinetics of a single dose of Aptensio XR® (methylphenidate hydrochloride extended-release) capsules under fed conditions in male or female children 4 to under 6 years of age with ADHD.
- Trial name
- PK003 (NCT02470234)
- Testing
- Methylphenidate HCl ER Capsules, 10 mg, Methylphenidate HCl ER Capsules, 15 mg, Methylphenidate HCl ER Capsules, 20 mg
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Rhodes Pharmaceuticals, L.P.
Attention Deficit and Disruptive Behavior Disorders, Attention Deficit Disorder With Hyperactivity
Effectiveness of the Quotient® ADHD Assessment in a System of Care
The study goal is to examine whether the use of an objective computerized neuroassessment (the Quotient System) for Attention-Deficit/Hyperactivity Disorder (ADHD) is related to improved outcomes among pediatric patients being…
- Trial name
- NCT02094612
- Testing
- Quotient®, Usual Clinic ADHD Care
- Where
- 3 sites in United States
- Volunteers
- 207 people
- Sponsor
- Kaiser Permanente
Attention Deficit/Hyperactivity Disorder, Inattention
Pilot Testing PREschooler Care, Community Resources, Advocacy, Referral, Education (PRE-CARE)
The goal of this proposed study is to pilot test a novel treatment model (PRE-CARE) addressing unmet social needs for families of preschool-age children with Attention Deficit/Hyperactivity Disorder (ADHD) symptoms.
- Trial name
- PRE-CARE (NCT04999982)
- Testing
- Screening, Resource Packet, Resource Navigation
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Attention Deficit Disorder With Hyperactivity
Efficacy of Lisdexamfetamine Dimesylate for Promoting Occupational Success in Young Adults With ADHD
There has been little research on the third area of impairment noted in the Diagnostic and Statistical Manual of Mental Disorders - "occupational functioning." Individuals with ADHD experience job-related impairments including a…
- Trial name
- NCT03446885
- Testing
- Lisdexamfetamine Dimesylate 40 MG
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Gregory Fabiano
ADHD - Inattentive Type, ADHD - Combined Type
Attention Deficit Disorder Medication Response Study
This study evaluates how children with Attention Deficit Disorder without Hyperactivity (ADD) respond to medication, and if their response is different from children who have problems with both hyperactivity and inattention.
- Trial name
- NCT01727414
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
ADHD
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) Low Dose in Adolescents With ADHD
This study will evaluate the efficacy and safety of low doses of SPN-812 in adolescents 12-17 years of age.
- Trial name
- NCT03247517
- Testing
- 200mg SPN-812, 400mg SPN-812
- Where
- 12 sites in United States
- Volunteers
- 310 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
ADHD
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) High Dose in Adolescents With ADHD
This study will evaluate the efficacy and safety of high doses of SPN-812 in adolescents (12-17 years old) with ADHD
- Trial name
- NCT03247556
- Testing
- 400mg SPN-812, 600mg SPN-812
- Where
- 14 sites in United States
- Volunteers
- 297 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Attention Deficit Hyperactivity Disorder
Gene-environment Interactions and Brain Functional Connectivity in Attention Deficit Hyperactivity Disorder
The aims of the current study are to examine gene-environment interactions associated with norepinephrine (NE) system genes (ADRA2A, SLC6A2) in ADHD, and to evaluate whether genetic changes in norepinephrine pathway are…
- Trial name
- NCT01912352
- Testing
- Methylphenidate
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Attention Deficit Disorder
Effect of Omega-3 Fatty Acid on Cortical Function in ADHD
The study hypothesis is that DHA is more effective than placebo in increasing brain activation and reducing symptoms in psychostimulant-free children with ADHD.
- Trial name
- NCT01883817
- Testing
- DHA Omega-3
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Attention Deficit Hyperactivity Disorder
CONCERTA Lab School Study
The purpose of this trial is to determine if the study medication, CONCERTA (methylphenidate HCl), is safe and effective in improving academic performance and behavior in children with Attention Deficit Hyperactivity Disorder…
- Trial name
- NCT00799487
- Where
- 3 sites in United States
- Volunteers
- 89 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
ADHD
Open-Label Pilot Study of Namenda in Adult Subjects With ADHD and ADHD NOS
The primary objective of the study is to assess the efficacy and tolerability of a 12-week trial of memantine hydrochloride administered twice daily in 20 adults (ages 18-55) with ADHD and ADHD NOS.
- Trial name
- NCT00586573
- Testing
- memantine hydrochloride
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Massachusetts General Hospital
ADHD
Refining the Shared Decision Making Process Survey in ADHD Medication Decisions
This is a retrospective observational survey study. We will survey a sample of adult parents or legal guardians who have a child who has been diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) and who discussed ADHD…
- Trial name
- NCT05048186
- Testing
- Attention Deficit Hyperactivity Disorder Treatment Decision Aid
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder (ADHD)
Safety, Tolerability, Pharmacokinetic, and Efficacy Study of SPD489 in Preschool Children With Attention-deficit/Hyperactivity Disorder
The purpose of this study is to gain initial safety, tolerability, pharmacokinetic, and efficacy information on SPD489 in preschool children 4-5 years old who are diagnosed with ADHD.
- Trial name
- NCT02402166
- Testing
- SPD489
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- Shire
Attention Deficit Hyperactivity Disorder
Mobile Behavioral Parent Training for Childhood ADHD: A Micro-randomized Trial
The goal of the study is to develop and refine a personalized behavioral parent training intervention for caregivers of children with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT06012851
- Testing
- Mobile behavioral parent training (mBPT), In the moment feedback, In the moment suggestions
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Florida International University
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders
The objective of this K01 study was to pilot a sequential, multiple assignment, randomized trial (SMART) design to compare the impact of a sequence of sleep interventions, based on participant treatment response, to optimize…
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Sleep Disturbance
- Trial name
- NCT03730194
- Testing
- Melatonin, Bedtime Bank
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Attention Deficit Hyperactivity Disorder
Long Acting Stimulant Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Young Children
This is a pilot study evaluating the effectiveness, safety, and tolerability of Ritalin LA in treating Attention Deficit Hyperactivity Disorder (ADHD) in 4 and 5 year old children.
- Trial name
- NCT00754208
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Nebraska
Attention Deficit Hyperactivity Disorder
Large-scale Brain Organization During Cognitive Control in ADHD
The purpose of this study is to test whether children with attention-deficit/hyperactivity disorder (ADHD) are impaired in the ability to flexibly adapt brain network organization in response to shifting cognitive demands during…
- Trial name
- NCT04349917
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of North Carolina, Chapel Hill
Attention Deficit Disorder With Hyperactivity, Conduct Disorder
Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder
Childhood ADHD and comorbid oppositional defiant disorder (ODD) and conduct disorder (CD) are considered risk factors for subsequent substance abuse, and youth with both ADHD and ODD/CD are at greatest risk.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Conduct Disorder, Substance Abuse
- Trial name
- NCT04170738
- Testing
- Adderall
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Jeffrey Newcorn
Conduct Disorder, Child
Virtual Reality to Improve Social Perspective Taking
This project will examine how virtual reality treatment that provides users with the alternate perspective of a virtual interpersonal interaction impacts psychological and neurobiological markers of social perspective taking in…
- Conditions
- Conduct Disorder, Child, Adolescent, Attention Deficit and Disruptive Behavior Disorders
- Trial name
- NCT03927612
- Testing
- Virtual reality perspective taking training, Virtual reality control perspective
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Indiana University
Attention Deficit Disorder
Neurofeedback and Working Memory Training for Children and Adolescents With ADHD
The purpose of this study is to investigate if neurofeedback and working memory training improves core symptoms of ADHD in children and adolescents.
- Trial name
- KITE (NCT01841151)
- Testing
- SCP training, Live Z-score training, WM training
- Where
- Sweden
- Volunteers
- 202 people
- Sponsor
- Karolinska Institutet