Clinical trials: Auditory Hallucinations
Schizophrenic Disorders
Interest of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Auditory Hallucinations
Auditory hallucinations are common (present in 60-70% of cases) and extremely debilitating. Behavioral disorders associated with them can have serious social repercussions.
- Trial name
- TMS HALLU (NCT02525315)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Auditory Hallucinations
Transcranial Magnetic Stimulation (TMS) for Treatment of Auditory Hallucinations
Transcranial magnetic stimulation (TMS) involves the use of magnetic fields to non-invasively stimulate the brain. Studies overseas have suggested this may be an effective and safe treatment for auditory hallucinations in…
- Trial name
- NCT00763841
- Testing
- Transcranial magnetic stimulation
- Where
- Australia
- Volunteers
- 18 people
- Sponsor
- The University of New South Wales
Schizophrenia
rTMS for Auditory Hallucinations Guided by Magnetoencephalography
rTMS and MEG for auditory hallucinations via self controlled clinical trials. Repetitive transcranial magnetic stimulation (rTMS) can increase or decrease cortical excitability in patients with psychosis (such as schizophrenia).
- Trial name
- NCT05598450
- Testing
- rTMS and MEG for auditory hallucinations via self controlled clinical trials
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Hallucinations, Auditory, Psychosis
Toward a Computationally-Informed, Personalized Treatment for Hallucinations
Auditory hallucinations are among the most distressing aspects of psychotic illness, and between 10 and 30% of people with hallucinations do not respond to antipsychotic medications.
- Trial name
- NCT04366518
- Testing
- Rivastigmine Transdermal System, Scopolamine
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Yale University
Psychotic Disorders
Efficacy of an Online-Based Self-Help Intervention for Auditory Hallucinations in Persons With Psychotic Disorders
The proposed clinical trial aims to examine the efficacy of an online-based self-help intervention for auditory hallucinations in persons with psychotic disorders.
- Trial name
- ECHION (NCT06186570)
- Testing
- Online-Based Self-Help Intervention
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- Charite University, Berlin, Germany
Schizophrenia
Basic Auditory Processing and Auditory Hallucinations
Schizophrenia is a severe psychiatric disorder that affects approximately 1% of the population worldwide. Although pathophysiology of this disease remains unclear, a growing interest is emerging for low-level sensory function…
- Trial name
- AUDISCHIZ (NCT02887794)
- Testing
- Clinical and psychoacoustic measures
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Hôpital le Vinatier
Schizophrenia
Treatment of Refractory Auditory Verbal Hallucinations With tDCS in Schizophrenia
The purpose of this study is to exploratively evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in patients with schizophrenia who experience persistent auditory verbal hallucinations after…
- Trial name
- NCT02451371
- Testing
- tDCS
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Seoul National University Hospital
Schizophrenia and Related Disorders
Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment
The purpose of the study is to test the hypothesis that functionally navigated repetitive TMS stimulations to the prefrontal cortex (PFC) modulate aberrant cortical electrical activities at PFC circuitry.
- Trial name
- NCT02916810
- Testing
- Active rTMS stimulation
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- The University of Texas Health Science Center, Houston
Schizophrenia
Efficacy of tACS for Treatment of Auditory Hallucinations in Refractory Schizophrenia
The aim of this study is to evaluate the feasibility and efficacy of transcranial alternating current stimulation (tACS) as an add-on treatment for auditory hallucinations in refractory schizophrenia.
- Trial name
- NCT05282329
- Testing
- Transcranial alternating Current Stimulation (tACS)-active
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tianjin Anding Hospital
Nurses, Schizophenia Disorder
The Effectiveness of Combining AR/VR Technology in Virtual Clinical Auditory Hallucinations on the Comprehensive Auditory Hallucination Nursing Competency of Psychiatric Nurses
This study aims to develop and evaluate a Virtual Reality (VR) Auditory Hallucination Program to enhance psychiatric nurses' comprehensive care competence in managing auditory hallucinations among patients with schizophrenia.
- Conditions
- Nurses, Schizophenia Disorder, Hallucinations, Auditory
- Trial name
- NCT06938997
- Testing
- Virtual clinical auditory hallucination solution combining AR/VR technology, Auditory Hallucination Care Video
- Where
- 4 sites in Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Schizophrenia
Study of Efficacy of PEAR-004 in Schizophrenia
The purpose of the study was to determine in patients currently being administered antipsychotic pharmacotherapy whether PEAR-004 could further reduce symptoms of schizophrenia as measured by the Positive and Negative Syndrome…
- Trial name
- NCT03751280
- Testing
- PEAR-004
- Where
- 6 sites in United States
- Volunteers
- 112 people
- Sponsor
- Novartis Pharmaceuticals
Hallucinations, Verbal Auditory
Virtual Reality Therapy for Voice Hearing (VR-VOICES): a Randomized Controlled Trial
Rationale: Auditory verbal hallucinations (AVH) - hearing voices that others cannot hear - are common in mental illnesses. For many people AVH are distressing, disabling and persistent, despite medication.
- Trial name
- VR-VOICES (NCT06013748)
- Testing
- VR-VOICES, Treatment as usual
- Where
- 3 sites in Netherlands
- Volunteers
- 112 people
- Sponsor
- University Medical Center Groningen
Schizophrenia, Auditory Hallucinations
A Pilot Double-blind Sham-controlled Trial of Repetitive Transcranial Magnetic Stimulation for Patients With Refractory Schizophrenia Treated With Clozapine
The primary outcome of this study is to evaluate the effects of low frequency subthreshold repetitive Transcranial Magnetic Stimulation applied to the left temporoparietal cortex of patients with refractory schizophrenia on the…
- Trial name
- NCT01015001
- Testing
- (1Hz) rTMS applied over the left temporoparietal cortex
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Auditory Hallucinations, Schizophrenia Spectrum
Cost-utility Study of Cognitive-behavioral Management of Auditory Hallucinations in Schizophrenic Disorder
The aim of the study is to assess the effectiveness and costs of a cognitive-behavioral treatment (CBT) for auditory hallucinations (psychotherapy) as an adjunct to usual care, comparing it to the effectiveness and costs of usual…
- Trial name
- VOICES (NCT07134816)
- Testing
- Cognitive and behavioral therapy for auditory hallucinations, Usual treatment
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Montpellier
Auditory Hallucination, Verbal, Treatment-resistant Schizophrenia
Comparaison of Avatar Therapy to Cognitive Behavioral Therapy in Schizophrenia With Treatment Refractory Hallucinations
Schizophrenia is associated with long-lasting health, social and financial burden for patients, families, caregivers and society.
- Trial name
- Phase3 (NCT04054778)
- Testing
- Avatar Therapy, Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Schizophrenia, Schizoaffective Disorder
Effect of Neuroplasticity Modulation in tDCS Treatment Response Among Schizophrenia Patients With Auditory Hallucination
Schizophrenia is a severe neuropsychiatric disorder of the brain and is also one of the top ten disabling diseases. A common symptom of schizophrenia (SCZ) is hearing voices inside one's heads which others do not.
- Trial name
- NCT04629352
- Testing
- Verum Accelerated Transcranial Direct Current Stimulation (acctDCS)
- Where
- India
- Volunteers
- 72 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Schizophrenia, Caregiver Burden
Effect of Simulation on Emotional Expression and Perceived Family Burden of Caregivers
The aim of this study is to determine the effect of Auditory Hallucination Based Voice Hearing Simulation on the emotional expression and perceived family burden of caregivers of individuals diagnosed with schizophrenia.
- Conditions
- Schizophrenia, Caregiver Burden, Expressed Emotion
- Trial name
- NCT06723977
- Testing
- Auditory Hallucination Based Voice Hearing Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Schizophrenia, Hallucinations, Auditory
Role of Inferior Colliculi in Auditory Hallucinations
The neural basis of auditory hallucinations (AH) in patients with schizophrenia is poorly characterized. Functional imaging studies investigate either the "state" dimension (i.e., the measurement of changes in brain area…
- Trial name
- SchizoHIC (NCT07003529)
- Testing
- Unenhanced brain MRI
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Schizophrenia; Psychosis
Efficacy of Maintenance Repetitive Transcranial Magnetic Stimulation (rTMS) in Auditory Verbal Hallucinations
Repetitive transcranial magnetic stimulation (rTMS) can alleviate persistent auditory verbal hallucinations (AVH) in schizophrenic patients, but the classical procedure with low-frequency stimulation for several weeks upon the…
- Trial name
- MAINSTIM (NCT05550155)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Auditory Hallucination, Psychotic Disorders
Avatar-mediated Therapy Versus Cognitive Behavioural Therapy for Persisting Experiences of Hearing Voices
The aim of this study is to compare the effects of a new psychological therapy, Avatar Therapy, to the current standard therapy, Cognitive Behavioural Therapy (CBT), in improving outcomes in people living with psychotic disorders…
- Conditions
- Auditory Hallucination, Psychotic Disorders, Schizophrenia and Related Disorders
- Trial name
- AMETHYST (NCT05982158)
- Testing
- Avatar therapy, Cognitive behavioural therapy (CBT)
- Where
- Australia
- Volunteers
- 212 people
- Sponsor
- Swinburne University of Technology