Clinical trials: Augmentation
Motion Sickness, Space, Motion Sickness
Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance
The primary specific aim is to evaluate the use of intranasal scopolamine gel and sensory augmentation as an integrated countermeasure to mitigate motion sickness and enhance sensorimotor performance.
- Conditions
- Motion Sickness, Space, Motion Sickness, Sea Sickness
- Trial name
- NCT05886660
- Testing
- DPI-386 Nasal Gel
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Osteochondral Defect
ReNu™ Marrow Stimulation Augmentation
To evaluate the use of ReNu™ allograft for the augmentation of marrow stimulation for osteochondral lesions
- Trial name
- NCT03036878
- Testing
- ReNu
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- NuTech Medical, Inc
Breast Reconstruction, Breast Reconstruction Following Mastectomy
Post-market Prospective Clinical Study of Nagor Perle Mammary Implants
Patients can undergo breast implant surgery for multiple reasons; cosmetic and reconstructive being the primary indications. In order to confidently state safety and due to strict regulation on medical devices it is important to…
- Conditions
- Breast Reconstruction, Breast Reconstruction Following Mastectomy, Breast Revision, Breast Augmentation
- Trial name
- PERLE10PMCF (NCT06013514)
- Testing
- PERLE Sterile Smooth Opaque gel filled mammary implants
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- GCA (Eurosilicone)
Augmentation, Augmentation Revision
Spectra Breast Implant Study
The purpose of this study is to demonstrate safety and effectiveness of Mentor's Spectra/Becker 80 Adjustable Breast Implants in women who are undergoing primary or revision breast augmentation.
- Conditions
- Augmentation, Augmentation Revision, General Breast Enlargement, Post-lactational Involution
- Trial name
- NCT00981266
- Testing
- Mentor Spectra/Becker 80 Breast Implant
- Where
- United States
- Sponsor
- Mentor Worldwide, LLC
Mid Face Volume Deficit
A Study to Assess Adverse Events and Change in Disease Activity of HArmonyCa Lidocaine Injectable Gel for Mid Face Soft Tissue Augmentation in Adult Participants
The cumulative effect of aging and environmental exposures (ie, ultraviolet, infrared, and visible light radiation and pollution) leads to wrinkles, discoloration, laxity, and roughness of sun exposed skin.
- Trial name
- NCT05452070
- Testing
- HArmonyCa Lidocaine Injectable Gel
- Where
- 12 sites in Canada, Spain and 1 more
- Volunteers
- 171 people
- Sponsor
- Allergan
Breast Implant Malposition, Breast Implant Rotation
Prospective Two-Year Cohort Study of Surgical and Implant Predictors of Breast Implant Displacement and Rotation After Aesthetic Augmentation
This prospective inception cohort will follow women for ten years after primary or revision aesthetic breast implantation. Pocket plane, incision route, implant texture, shape, volume, and operative pocket variables will be…
- Trial name
- NCT07810270
- Testing
- Aesthetic Breast Implantation, Standardized Implant Position Assessment
- Where
- Colombia
- Volunteers
- 3,000 people
- Sponsor
- Research Inc
Abnormal Lip
Study to Evaluate the Effectiveness, Safety and Long Term Safety of Saypha® FILLER Lidocaine for Lip Augmentation
This is a prospective, open-label, multicentre, randomized study conducted to evaluate the effectiveness, safety and long-term safety of Saypha® FILLER Lidocaine for lip augmentation.
- Trial name
- SayLip (NCT04917588)
- Testing
- Saypha® FILLER Lidocaine (HQ), Saypha® FILLER Lidocaine (C1)
- Where
- 3 sites in Austria
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Chin Retrusion
A Safety and Effectiveness Study of JUVÉDERM VOLUMA® XC Injectable Gel for Chin Augmentation
This is a safety and effectiveness study of JUVÉDERM VOLUMA XC injectable gel for chin augmentation to correct volume deficit in chin retrusion.
- Trial name
- NCT02833077
- Testing
- JUVÉDERM VOLUMA® XC
- Where
- 14 sites in United States
- Volunteers
- 221 people
- Sponsor
- Allergan
Cognitive Dysfunction, Schizophrenia
TC-5619 as Augmentation Therapy to Improve Cognition in Outpatients With Cognitive Dysfunction in Schizophrenia
Schizophrenia affects approximately 1% of the population worldwide, and in about 80% of cases, it is a lifelong, disabling illness.
- Trial name
- NCT01003379
- Testing
- TC-5619
- Where
- 16 sites in United States, India
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Targacept Inc.
Hepatic Biopsy or Ablation
Modality Augmentation for Navigation: Intuitive Fusion With Optical Lightweight Device (US/CBCT)
The objective of this research is to evaluate functional validation of the CBCT-US fusion for the Clear Guide SCENERGY system, as well as to evaluate benefits derived from system performance.
- Trial name
- MANIFOLD II (NCT03231046)
- Testing
- CBCT-US Fusion Arm, Hepatic Biopsy or Ablation
- Sponsor
- Clear Guide Medical
Breast Augmentation
Improved Breast Enlargement Using the Subject's Own Fat Tissue
The goal of this clinical study is to learn if the Medical Device Under Investigation (simply "the device") is safe to use in human adults undergoing breast augmentation surgery.
- Trial name
- SWIFT (NCT07869641)
- Testing
- An injectable, biodegradable hydrogel, in reconstitution medium, Reconstitution medium
- Where
- 2 sites in Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- 4Tissue
Ischemic Stroke
Implant for Augmentation of Cerebral Blood Flow Trial, Effectiveness and Safety in a 24 Hour Window
The primary objective of the study is to assess the safety and effectiveness of SPG stimulation with the ISS in patients with an acute ischemic stroke in the anterior circulation initiated within 24 hours from stroke onset.
- Trial name
- ImpACT-24B (NCT00826059)
- Testing
- Active Sphenopalatine Ganglion (SPG) Stimulation
- Where
- 73 sites in United States, Canada and 16 more
- Volunteers
- 1,078 people
- Sponsor
- BrainsGate
Alveolar Ridge Defect
CopiOs® Pericardium Membrane for Localized Alveolar Ridge Augmentation
This is a prospective, multi-center study to evaluate the use of CopiOs Pericardium Membrane, a bovine xenograft, with use of Puros Cancellous Particulate Allograft, for the augmentation of localized alveolar ridge defects on…
- Trial name
- NCT00889265
- Testing
- CopiOs Pericardium Membrane
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Zimmer Biomet
Schizophrenia, Cognition
Efficacy Study Exploring the Effect of Lu AE58054 as Augmentation Therapy in Patients With Schizophrenia
The objective of this study is to explore the efficacy, safety and cognitive properties of Lu AE58054 as augmentation therapy to risperidone in patients with schizophrenia.
- Trial name
- NCT00810667
- Testing
- Lu AE58054
- Where
- 25 sites in Belgium, France and 6 more
- Volunteers
- 124 people
- Sponsor
- H. Lundbeck A/S
Depressive Disorder, Major
A Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive Disorder
The primary purpose is to study the efficacy, safety, and tolerability of LY2216684 as an adjunctive treatment for participants with major depressive disorder (MDD), who were identified as partial responders to an adequate course…
- Trial name
- NCT00840034
- Testing
- LY2216684
- Where
- 24 sites in United States
- Volunteers
- 227 people
- Sponsor
- Eli Lilly and Company
Cheek Wrinkles, Midface Contour Deficiencies
Safety and Effectiveness of GP0112 for Cheek Augmentation and Correction of Midface Contour Deficiencies
A randomized, evaluator-blinded, parallel group, comparator-controlled, multicenter study to evaluate the safety and effectiveness of GP0112 for cheek augmentation and correction of midface contour deficiencies
- Trial name
- NCT05262777
- Testing
- GP0112, Restylane Lyft Lidocaine
- Where
- 15 sites in Canada
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Pathologic Fracture of the Vertebra Due to Osteoporosis
Clinical Evaluation of the Crosstrees Pod™ in the Treatment of Pathologic Fracture of the Vertebral Body (Levels T4 - L5) in Adult Patients
The clinical trial is being conducted to evaluate the performance of the Crosstrees System in reducing pain and decreasing the risk of cement leakage associated with vertebroplasty and kyphoplasty.
- Trial name
- NCT00933036
- Testing
- Crosstrees Pod system for PVA
- Where
- 9 sites in United States
- Volunteers
- 135 people
- Sponsor
- Crosstrees Medical Inc.