Clinical trials: Augmentation
Edentulous Alveolar Ridge With Labial Resorption
Extraction Socket Augmentation. A Clinical Study
Extraction socket preservation is defined as alveolar ridge preservation within the bone envelope remaining after tooth extraction, meanwhile ridge augmentation is defined as increasing the volume of alveolar ridge beyond the…
- Trial name
- GTO (NCT06378112)
- Testing
- GTO®
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Alveolar Cleft Grafting
Alveolar Cleft Grafting Using Two Different Alloplastic Grafts
P-patients with unilateral alveolar clefts I-purabone with -β-tricalcium phosphate graft C-β-tricalcium phosphate graft alone O-clinical out come Outcome name Measurement device Measurement unit Esthetic satisfaction (Primary…
- Trial name
- NCT03016793
- Testing
- Puerarin, β- tricalcium phosphate, β- tricalcium phosphate alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sinus Floor Augmentation, Maxillary Sinus
Prospective Evaluation of Anorganic Bovine Bone Mineral Versus Calcium Phosphosilicate Alloplastic Bone Putty in Direct Sinus Augmentation: a Spilt-mouth Study
The purpose of this split-mouth clinical study is to evaluate the clinical, radiographic and histological outcomes of lateral window sinus augmentation with a bovine xenograft or a CPS putty bone substitute in posterior maxillary…
- Trial name
- NCT01942304
- Testing
- Calcium phosphosilicate alloplastic bone putty in direct sinus augmentation, Anorganic bovine bone mineral in direct sinus augmentation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Minnesota
Volume Responsiveness
Correlation of Carotid Flow Time and Cardiac Output.
Assessment of common carotid artery flow is more easily done and can be taught more broadly than transthoracic echocardiography, providing a greater number of clinicians a tool to assess volume responsiveness.
- Trial name
- NCT04614701
- Testing
- Carotid Artery Ultrasound Measure
- Where
- Canada
- Sponsor
- St. Boniface Hospital
Bone Resorption Disorder
Guided Bone Regeneration in Atrophic Anterior Maxillary Ridges
This study is aiming to evaluate clinically, radiographically ,and histologically GBR using collagen membrane in combination with a mixture of ABBM and autogenous particulated bone compared to collagen membrane with ABBM in…
- Trial name
- NCT03731416
- Testing
- GBR by xenograft and autogenous bone
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Substance Use Disorders
Entolimod, an Adjuvant for Vaccine Augmentation
The primary objective of this pilot study to evaluate the safety of low dose Entolimod in normal, healthy, non-patient normals. This clinical trial in 40 normal humans compares a single dose of 4 ug Td (2 ug of TT and 2 ug of…
- Trial name
- NCT03063736
- Testing
- Entolimod, Td Vaccine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Physiological Parameters
Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients
The study aims to determine the effect of implementing cough augmentation techniques on weaning outcomes among critically ill patients
- Trial name
- NCT07722260
- Testing
- cough augmentation techniques
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Heba.Attia@nur.dmu.edu.eg
Full-thickness Rotator Cuff Tear
Dermal Allograft Augmentation of Large and Massive Rotator Cuff Tears
The purpose of this study is to compare postoperative healing of large and massive rotator cuff tears with preoperative MRI confirmed fatty infiltration stage II and higher repaired with or without dermal allograft augmentation…
- Trial name
- NCT05981833
- Testing
- Repair with DAA (dermal allograft augmentation)
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Arthrex, Inc.
Horizontal Ridge Deficiency
Assessment of GBR in Augmentation of Horizontally Atrophic Maxillary Ridge Using Collagen Membrane Versus Using Titanium Mesh
this study is aiming to Assess postoperative complications and bone quality and quantity in augmentation of horizontally atrophic maxillary ridge using a 1:1 mixture of autograft and xenograft particulate bone covered with…
- Trial name
- NCT03635658
- Testing
- titanium mesh, collagen membrane (Sausage technique)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acellular Dermal Matrix, Bone Grafting
Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix
This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.
- Conditions
- Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
- Trial name
- NCT07613047
- Testing
- Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obsessive-Compulsive Disorder
Risperidone or Cognitive-Behavioral Therapy for Improving Medication Treatment for Obsessive-compulsive Disorder
This study will compare the short- and long-term effectiveness of two common therapies in improving serotonin reuptake inhibitor treatment in people with obsessive-compulsive disorder.
- Trial name
- NCT00389493
- Testing
- Risperidone, Exposure/ritual prevention therapy (EX/RP)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- New York State Psychiatric Institute
Lip Augmentation and Correction of Perioral Rhytids
Injection Technique Assessment of Restylane Silk With Lidocaine for Lip Augmentation
This is a multi-center, open-label, single-arm study to assess the safety of an injection technique with Restylane Silk in lip augmentation and correction of perioral rhytids .
- Trial name
- NCT02703948
- Testing
- Restylane Silk with Lidocaine
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Alveolar Bone Loss, Alveolar Ridge Augmentation
Evaluation of Guided Tissue Regeneration With Autogenous Bone Chips and CGF During Implant Placement
CGF membranes will be prepared using a swing-lock centrifuge. A full-thickness mucoperiosteal flap will be elevated in a narrow alveolar ridge. Implants will be inserted.
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Augmentation, Dental Implant
- Trial name
- CGF (NCT07521514)
- Testing
- concentrated growth factor (CGF) Membrane
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Horizontal Bone Augmentation
A 1-year Clinical Investigation on the the CREOS™ XENOGAIN Bone Graft SUBSTITUTE
This clinical investigation is a prospective, multi-centre study to evaluate bone gain after horizontal augmentation using creos xenogain bone graft substitute.
- Trial name
- NCT03028922
- Testing
- creos xenogain
- Where
- 6 sites in Germany, Italy and 1 more
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Obsessive-Compulsive Disorder
Study of Memantine Augmentation in Severe Obsessive-Compulsive Disorder
Memantine is a glutamate receptor antagonist that has been reported to reduce Obsessive-Compulsive Disorder (OCD) symptoms in case studies of treatment-resistant individuals.
- Trial name
- NCT00869505
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Horizontal Alveolar Ridge Augmentation
Four Different Guided Bone Regeneration Strategies for Horizontal Ridge Augmentation in the Maxillary Esthetic Zone With Simultaneous Implant Placement: a Randomized Clinical Trial
This randomized clinical trial aims to evaluate and compare the clinical and radiographic outcomes of four different bone regeneration strategies for horizontal alveolar ridge augmentation with simultaneous dental implant…
- Trial name
- NCT07885748
- Testing
- Titanium Mesh-Guided Bone Regeneration, Extended Sticky Bone Augmentation, Medpark Bone Graft Augmentation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Major Depressive Disorder
N-methyl-D-aspartate Antagonist (Ketamine) Augmentation of Electroconvulsive Treatment for Severe Major Depression
Electroconvulsive therapy (ECT), is considered the most effective treatment for severe treatment resistant major depressive disorder (MDD), but it requires about 3 weeks of treatments and can cause considerable acute deficits in…
- Trial name
- NCT01260649
- Testing
- ketamine, IV Saline, ECT
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Massachusetts General Hospital
Horizontal Alveolar Bone Defect, Guided Bone Regeneration
Guided Bone Regeneration in Lower Posterior Edentulous Arch Using Resorbable or Non Resorbable Membrane.
the purpose of this study is to compare the efficiency of non-resorbable membrane versus resorbable membrane in guided bone regeneration in atrophic posterior mandible.
- Trial name
- NCT07254494
- Testing
- guided bone regeneration using Resorbable membrane pericardium, guided bone regeneration using non resorbable ptfe membrane
- Where
- Lebanon
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Depressive Disorder
Augmentation of Interpersonal Psychotherapy With High-Definition Transcranial Direct Current Stimulation for Adolescent Depression
Depression is among the most prevalent psychiatric disorders, with an upward trend in its manifestation in younger individuals. In contrast to adult depression, adolescent depression often presents with longer attack durations…
- Trial name
- NCT06061653
- Testing
- IPT plus HD-tDCS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Dental Implants, Humans
Atraumatic Zirconia Abutment Versus Customized Composite Healing Abutment in Maxilla or Mandible.
40 patients are included in the study, 20 patients in group 1 (=closure with composite material shaper; test group) and 20 patients in group 2 (=closure with custom-made zirconia oxide abutment; control group).
- Conditions
- Dental Implants, Humans, Dental Implants, Single-Tooth, Male
- Trial name
- NCT05748379
- Testing
- Kompozite closure, Individual abutment
- Where
- Latvia
- Volunteers
- 44 people
- Sponsor
- SIA Adenta