Clinical trials: Augmentation
Bone Augmentation, Alveolar Ridge Augmentation
Alveolar Ridge Reconstruction in Post-extraction Sites Using a Magnesium Resorbable Membrane. An Explorative Study
When a tooth is removed, the surrounding bone and gum tissue naturally shrink over time. This shrinkage can make it harder to place a dental implant later and may affect the appearance of the smile.
- Trial name
- NOVAMAG-2024 (NCT07646795)
- Testing
- NOVAMag®
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Martina Stefanini
Breast Augmentation and Breast Reconstruction, Mammaplasty
Clinical Study on Tissue Preservation in Breast Augmentation and Reconstruction
This clinical study aims to evaluate the safety and effectiveness of advanced, minimally invasive techniques for breast augmentation and reconstruction.
- Conditions
- Breast Augmentation and Breast Reconstruction, Mammaplasty, Breast Augmentation, Tissue Preservation
- Trial name
- NCT07623564
- Testing
- Mia Harmonization, Mia Scarless Lift, Mia Reconstruction
- Where
- Costa Rica
- Volunteers
- 60 people
- Sponsor
- Establishment Labs
Peri-Implant Health, Peri-Implant Tissues
Volumetric Analysis of Peri-Implant Soft Tissue Changes Between Polyethereketone(PEEK) Anatomic Healing Abutments and Standard Healing Abutments in Posterior Single Implant Restorations
This prospective randomized clinical trial will evaluate the clinical outcomes of the implant crown fabricated with standard scan body (control) and polyetheretherketone (PEEK) anatomic healing abutment (test).
- Conditions
- Peri-Implant Health, Peri-Implant Tissues, Soft Tissue Augmentation at Dental Implants
- Trial name
- anatomic (NCT07624331)
- Testing
- AHA PEEK, standard healing abutment
- Where
- Malaysia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- DR NUR HAFIZAH KAMAR AFFENDI
Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance
Safety and Performance of Motiva® Sizers
The Motiva® Sizer clinical study is a four-year, multicenter, post-marketing, and cohort study, designed to confirm the safety and performance of Motiva® Sizer in breast augmentation or reconstruction procedures.
- Conditions
- Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance, Mammaplasty, Breast Reconstruction
- Trial name
- NCT06274736
- Testing
- Motiva Sizer
- Where
- Costa Rica
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Establishment Labs
Chin Augmentation, Chin Retrusion
Safety and Effectiveness of Restylane Lyft With Lidocaine for Augmentation of the Chin Region to Improve the Chin Profile
The primary objective of the study was to demonstrate non-inferiority of Restylane Lyft with Lidocaine versus a comparator-control for augmentation of the chin region to improve the chin profile.
- Trial name
- NCT05777759
- Testing
- Restylane Lyft with Lidocaine, Juvederm Voluma XC
- Where
- 12 sites in United States, Puerto Rico
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Peri-implant Soft Tissue Augmentation, Dental Implant Rehabilitation
Soft Tissue Augmentation Around Dental Implants
The goal of this study is to determine which method better increases the volume of soft tissues (gums) around dental implants: using the patient's own tissues or applying collagen matrices.
- Trial name
- NCT07605286
- Testing
- Connective Tissue Graft (Palate), Connective Tissue Graft (Tuberosity), Fibro-Gide Collagen Matrix
- Where
- Russia
- Volunteers
- 84 people
- Sponsor
- Andrey Vasilyev
Atrophic Edentulous Maxilla, Zygomatic Implants
Assessment of Soft Tissue Thickness Over Zygomatic Implants in Atrophied Maxilla Covered With Buccal Fat Pad vs. Palatal Pedicle Flap
Background and Rationale The rehabilitation of the severely atrophied maxilla utilizing zygomatic implants is a highly predictable and effective treatment modality.
- Conditions
- Atrophic Edentulous Maxilla, Zygomatic Implants, Dental Implant, Soft Tissue Augmentation at Dental Implants
- Trial name
- NCT07574606
- Testing
- Palatal pedicle over zygomatic implant, covering zygomatic implants using buccal fat pad
- Where
- Egypt
- Volunteers
- 4 people
- Sponsor
- Future University in Egypt
Lip Augmentation
A Study to Evaluate the Safety and Performance of Dr Korman Laboratories' Hyaluronic Acid Filler 20 mg/mL With Lidocaine for Lip Augmentation
This study will assess the safety and effectiveness of a dermal filler called DKL crosslinked hyaluronic acid 20 mg/mL with lidocaine 0.3% when injected into the lips of healthy men and women who want to have fuller lips.
- Trial name
- NCT07204691
- Testing
- DKL crosslinked sodium hyaluronate 20 mg/mL + Lidocaine 0.3% dermal filler
- Where
- 2 sites in Sweden
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Bone Healing, Augmentation
Healing After Augmentation of Alveolar Ridge Using Collagen Membrane
One of the prerequisites for successful prosthetic implant therapy of patients is achieving the initial stability of the embedded implant, which largely depends on the width alveolar ridge, at the place of its installation.
- Conditions
- Bone Healing, Augmentation, Augmentation, Alveolar Ridge
- Trial name
- NCT06885983
- Testing
- implant placement, Guided bone regeneration
- Where
- Serbia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Immediate Dental Implant Placement, Dental Implant
Influence of Acellular Dermal Matrix on Peri-implant Soft Tissue Phenotype and Marginal Bone Loss
To evaluate soft tissue augmentation using acellular dermal matrix (ADM) over immediately placed dental implants in anterior maxilla.
- Conditions
- Immediate Dental Implant Placement, Dental Implant, Acellular Dermal Matrix, Polytetrafluoroethylene
- Trial name
- ADM (NCT07573020)
- Testing
- Polytetrafluoroethylene coverage, Acellular Dermal Matrix
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Mansoura University
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma
Lip Volume Enhancement, Lip Augmentation
A Post-Marketing Study of Alexa Medium for Сorrection of the Lips Volume Loss
This post-marketing, prospective, multicentre, single-arm, open-label clinical investigation aimed to evaluate the safety, tolerability, and effectiveness of the injectable medical device Alexa Medium (based on cross-linked…
- Conditions
- Lip Volume Enhancement, Lip Augmentation, Aesthetic
- Trial name
- AL-MED (NCT06961305)
- Testing
- Cross-linked Hyaluronic Acid Gel
- Where
- 4 sites in Poland, Ukraine
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Institute Hyalual GmbH
Soft Tissue Augmentation Around Dental Implants
Porcine Derma for Soft Tissue Augmentation Around Implants
Brief description of the study objectives The present study aims to evaluate the effectiveness of the porcine-derived collagen matrix Derma OsteoBiol® for peri-implant soft tissue augmentation.
- Trial name
- CT (NCT07436091)
- Testing
- Soft tissue augmentation with Derma OsteoBiol® around dental implants.
- Where
- Portugal
- Volunteers
- 15 people
- Sponsor
- Universidade do Porto
Soft Tissue Augmentation at Dental Implants
Assessment of Soft Tissue Thickness Following Utilization of Buccal Pad of Fat Versus Platelet-rich Fibrin for Covering Zygomatic Implants: A Randomized Clinical Trial
Would buccal pad of fat be comparable to platelet rich fibrin for Zygomatic implant coverage as a step for reconstruction of atrophic posterior maxilla, in terms of peri-implant soft tissue thickness and avoiding complicated…
- Trial name
- NCT07562334
- Testing
- Coverage with PRF for Zygomatic implant placed
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Arthroscopic Rotator Cuff Repair, Augmentation
Long Term Clinical Outcome After Arthroscopic Rotator Cuff Repair Augmentation With Autologous Microfragmented Lipoaspirate Tissue
Specific Aims : The aim of this prospective randomized controlled single-blind clinical trial was to evaluate the safety and efficacy of autologous microfragmented lipoaspirate tissue in arthroscopic rotator cuff repair.
- Conditions
- Arthroscopic Rotator Cuff Repair, Augmentation, Microfragmented Adipose Tissue
- Trial name
- NCT06960343
- Testing
- magnetic resonance imaging (MRI), VAS, SST, ASES, CMS scores, and strength measurements in external rotation and abduction
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Milan
Restless Legs Syndrome, Augmentation
Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist
This is an exploratory, double blinded cross-over study of the D1 antagonist ecopipam treat patients currently having dopamine agonist induced augmentation in restless legs syndrome.
- Trial name
- RLS-Ecopipam (NCT03218969)
- Testing
- Ecopipam
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- William Ondo, MD
Maxillary Sinus Floor Augmentation
Evaluation of Tenting the Schneiderian Membrane of the Maxillary Sinus Using Titanium Mesh.
Twenty posterior maxillary edentulous sites requiring open sinus augmentation for staged dental implant placement will be studied.
- Trial name
- NCT07035236
- Testing
- maxillary sinus lifting
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Penile Girth Augmentation, Fat Graft
Efficacy and Stability of Autologous Fat Grafting for Penile Girth Augmentation
The primary aim of this study is to evaluate the clinical and radiological efficacy and long-term stability of autologous fat grafting as a method for girth augmentation.
- Trial name
- NCT07547839
- Testing
- Autologous Fat Grafting
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ridge Augmentation
Magnesium NOVAMag® Membrane vs. Collagen Jason® Membrane in Patients Requiring Guided Bone Regeneration
The NOVAMag® membrane is a medical device approved in the EU, and is a completely resorbable and biodegradable metal membrane. This medical device is used in the treatment of bone defects in the oral cavity.
- Trial name
- NCT06059898
- Testing
- GBR surgery including membrane placement, Biopsy
- Where
- 5 sites in Austria, Denmark and 1 more
- Volunteers
- 106 people
- Sponsor
- Botiss Medical AG
Guided Bone Regeneration, Bone Augmentation
Lateral GBR Using Two Types of Membrane With a Combination of Allograft-xenograft
Bone width is critical for successful implant placement, as thin bone increases the risk of bone loss. Various augmentation techniques-especially guided bone regeneration (GBR)-are effective in restoring bone volume using grafts…
- Trial name
- NCT07525128
- Testing
- Lateral Guided bone regeneration
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University