Clinical trials: Augmentation
Vertebral Fracture, Kyphoplasty
Porous Titanium Microspheres in Kyphoplasty
Study is a prospective observational, performed in the context of normal clinical practice, of patients with osteoporotic vertebral compression fractures identified as candidates for kyphoplasty treatment with porous trabecular…
- Trial name
- NCT05815251
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Unit of neurosurgery, Departement of Neurosciences, University of Torino
Alveolar Ridge Deficiency
Horizontal Ridge Augmentation With Demineralized Bone Allograft Layered With Xenograft - a Prospective Clinical Study
The aim of this case series is to evaluate the outcomes of horizontal ridge augmentation performed using a combination of demineralized freeze-dried bone allograft layered with xenograft bone with a resorbable native collagen…
- Trial name
- NCT06342973
- Testing
- Xenograft and allograft
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Bone Loss, Missing Teeth
The Use of Bio-Oss Collagen for Sinus Augmentation Using the Transcrestal Approach.
To assess vertical bone height gain with Geistlich Bio-Oss Collagen used in conjunction with simultaneous implant installation in transcrestal approach sinus augmentation.
- Trial name
- NCT04581304
- Testing
- Geistlich Bio-Oss® Collagen, Geistlich Bio-Oss® Granules
- Where
- Israel
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Augmentation
Using the Roots of a Non Restorable Wisdom Tooth as a Block for Augmentation of Localized Defects
assess and compare the efficacy and safety of autogenous tooth roots for lateral alveolar ridge augmentation with staged implant placement in comparison to autogenous bone block.
- Trial name
- Clinical (NCT04266652)
- Testing
- tooth block, autogenous bone block
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Ain Shams University
Schizo-affective Disorder, Bipolar Disorder
Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders
The purpose of this study is to assess the efficacy of oral glycine as an augmentation strategy in two psychotic patients with a triplication (4 copies) of the gene glycine decarboxylase (GLDC).
- Trial name
- NCT01720316
- Testing
- Glycine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mclean Hospital
Dental Implant, Bone Loss
Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor
This study will compare two techniques to achieve increase in ridge dimensions as a preparation for dental implants using a resorbable barrier membrane and bone particulate allogenic graft hydrated with saline or a growth factor…
- Trial name
- NCT04954664
- Testing
- Allograft particles hydrated with rhPDGF, Allograft particles hydrated in a conventional way with saline.
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Jaw, Edentulous, Partially, Acquired Absence of Single Tooth
Esthetic, Clinical and Radiographic Outcomes of Immediate and Delayed Implant Placement
The aim of this prospective cohort study is to compare the esthetic, clinical and patient-centered outcomes following immediate and delayed implant placement protocols.
- Trial name
- NCT02814149
- Testing
- Type 1 implant placement, Type 3 implant placement
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Alveolar Ridge Augmentation, Tissue Transplantation
Peri-implant Tissue Stability Following Tissue Augmentation Harvested From Deep Palate or Tuberosity
This study will compare peri implant tissue stability following connective tissue graft harvested fromLateral Palate or the Tuberosity Area.
- Conditions
- Alveolar Ridge Augmentation, Tissue Transplantation, Tissue Donors
- Trial name
- NCT05014763
- Testing
- connective tissue graft
- Where
- Iran
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Chin Retrusion, Chin Augmentation
A Study to Evaluate the Safety and Efficacy of Restylane Defyne for Chin Augmentation and Correction of Chin Retrusion
To demonstrate the effectiveness of Restylane Defyne for chin augmentation and correction of chin retrusion by demonstrating the superiority in responder rates relative to no treatment.
- Trial name
- NCT03624816
- Testing
- Restylane Defyne
- Where
- 11 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Depressive Disorder, Major
Identifying Very Early Response to Seroquel Extended Release (XR) Augmentation for Major Depressive Disorder
The proposed study is for a 6 week open-label clinical trial in which Seroquel XR is added to a selective serotonin reuptake inhibitor (SSRI) medication for the treatment of depressive and/or anxiety symptoms.
- Trial name
- NCT00892463
- Testing
- Quetiapine (Seroquel) XR
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Sunnybrook Health Sciences Centre
Restless Legs Syndrome
Suggested Immobilization Test (SIT) Test for Early Detection of Restless Legs Syndrome (RLS) Augmentation - Proof of Concept
Some medications used to treat the restless legs syndrome (RLS) when taken for some time make the condition worse. This study seeks to find a method for early detection of this problem so that it can either be prevented or…
- Trial name
- NCT00867893
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Johns Hopkins University
Horizontal Ridge Deficiency
Buccal Cortical Separation and Lateralization for Horizontal Ridge Augmentation
Cases with horizontal ridge deficiency less than what is possible for ridge splitting were recruited and the buccal cortex was totally separated and lateralized at the desired distance for augmentation
- Trial name
- NCT05286541
- Testing
- Lateralized buccal cortex with xenograft, Lateralized buccal cortex with autogenous particulate
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Graft; Complications, Infection or Inflammation, Ridge Deficency
To Compare Different Soft Tissue Grafts at the Time of Lateral Ridge Augmentation Procedure.
This study will compare two commonly used soft tissue grafting techniques (connective tissue graft, CTG vs Acellular Dermal Matrix, ADM) to augment the soft tissue at the time of lateral ridge augmentation procedure.
- Conditions
- Bone Graft; Complications, Infection or Inflammation, Ridge Deficency, Dental Implant
- Trial name
- NCT03774888
- Testing
- Connective tissue graft at time of bone graft, Acellular Demal Matrix at time of bone graft, No soft tissue grafting at time of bone graft
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Posterior Mandible With Deficient Ridge Width
Evaluation of Horizontal Mandibular Ridge Augmentation Through Subperiosteal Tunneling by Using Bovine Sticky Bone (Radio-Histological Study)
This clinical trial evaluated horizontal ridge augmentation in the posterior mandible using subperiosteal tunneling with enriched bovine bone graft matrix (sticky bone).
- Trial name
- NCT07353086
- Testing
- Ridge augmentation with enriched bovine sticky bone through the subperiosteal tunneling technique in the posterior mandible
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Maternal Obesity During Childbirth, Labor; Arrested Active Phase
Impact of Maternal BMI on Plasma Levels of Oxytocin During Labor Augmentation
The aim of this study is to examine the associations between maternal BMI and levels of oxytocin in maternal plasma during augmentation with oxytocin during first stage of labor in term pregnancy.
- Trial name
- NCT04093479
- Testing
- blood samples
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Linkoeping University
Dental Implant, Immediate Dental Implant
Esthetic Outcomes Following Immediate Implant Combine With Soft Tissue Augmentation
The purpose of this study is to evaluate the esthetic outcomes following immediate implant combined with the autogenous tissue graft or acellular dermal matrix compared to immediate implant alone.
- Conditions
- Dental Implant, Immediate Dental Implant, Soft Tissue Augmentation
- Trial name
- NCT02864862
- Testing
- Immediate implant, SCTG, ADM
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- The University of Texas Health Science Center, Houston
Edentulous Alveolar Ridge
Long-term Follow up of Mucosal Tissue Height Influence on Peri-implant Bone Levels.
Our study looks into how the thickness of the gum tissue affects the health of the bone around dental implants over ten years. We include 59 people and divide them into three groups based on their gum tissue thickness.
- Trial name
- NCT06302322
- Testing
- Thin Tissues, Thick Tissues, Surgically augmented thin tissues
- Where
- Lithuania
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Missing Teeth
Lateral Ridge Augmentation Using Autogenous Bone Blocks or Xenogenic Bone Block Grafts Loaded With Recombinant Human Bone Morphogenic Protein 2
Since there are no clinical studies available comparing the gold standard (autogenous bone graft plus resorbable membrane) to the promising combination of xenogenic bone graft loaded with rhBMP-2 in combination with a collagen…
- Trial name
- NCT01541345
- Testing
- Autogenous bone graft, InductOs, Augmentation surgery
- Where
- 2 sites in Austria, Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Sinus Perforation
Computer Guided Low Window Sinus Lift Technique
The study group included 12 patients that were treated using the low window lateral sinus lift technique with simultaneous implant placement. This was facilitated using a CAD-CAM generated surgical guide.
- Trial name
- NCT04618588
- Testing
- Low Window Sinus Lift technique
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Bulimia Nervosa
Topiramate Augmentation in Bulimia Nervosa Partial Responders
The goal of this study is to generate pilot data exploring the addition of an augmentation (additional) medication to patients suffering from bulimia nervosa who have responded but not had complete symptom resolution with a…
- Trial name
- NCT00988481
- Testing
- Topiramate
- Where
- United States
- Sponsor
- Neuropsychiatric Research Institute, Fargo, North Dakota