Clinical trials: Auricular Stimulation
Healthy Volunteers
Effect of Recording Duration on Heart Rate Variability During taVNS
This study aims to evaluate how different heart rate variability (HRV) recording durations reflect autonomic nervous system responses during transcutaneous auricular vagus nerve stimulation (taVNS) in healthy adults.
- Trial name
- taVNS-HRV (NCT07526415)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sinop University
Vagus Nerve Stimulations
Acute Cardiovascular Effects of Transcutaneous Auricular Vagus Nerve Stimulation
Introduction Cardiovascular disease (CVD) remains the leading cause of mortality worldwide, with arterial hypertension representing the most significant modifiable risk factor (Lim et al., 2012; Mills et al., 2020).
- Trial name
- NCT07501611
- Testing
- Active taVNS condition
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Paresis
Pupil-Indexed Noninvasive Neuromodulation
Vagus nerve stimulation (VNS) is thought to activate neural pathways that release chemicals which promote plasticity and learning.
- Trial name
- NCT06282406
- Testing
- Transcutaneous Electrical Stimulation
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Experimental Pain in Healthy Human Subjects
Tonic Pain and Transauricular Vagal Nerve Stimulation
This study aims to explore the effect of burst-taVNS (electric stimulation of the concha cymba) on tonic (capsaicin-induced skin pain) and acute (pressure pain sensitivity) experimental pain and cardioception.
- Trial name
- NCT07325058
- Testing
- taVNS, Earlobe Stimulation
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Appetite Regulation, Food Intake
Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Appetite
This study tests a new way to help control appetite. Researchers will use a wearable device on the ear. This device sends gentle electrical pulses to a nerve. This is called vagus nerve stimulation.
- Conditions
- Appetite Regulation, Food Intake, Obesity, Eating Behaviour
- Trial name
- NCT07444177
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Health People, Physical Activity
The Effect of Auricular Vagus Nerve Stimulation and Controlled Breathing Exercises on Performance and Autonomic Nervous System
There are many studies in the literature on transcutaneous vagus nerve stimulation (VNS) and controlled breathing exercises (CBE), but there are limited studies examining the effects of both interventions on performance and the…
- Conditions
- Health People, Physical Activity, Autonomic Nerveus System, Vagus Nerve Stimulations
- Trial name
- NCT06796101
- Testing
- Vagus Nerve Stimulation, Controlled breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Pupillary Response
taVNS on Pupillary Response and Perceptual Learning
This study has two parts. The study team will evaluate transcutaneous auricular vagal nerve stimulation (taVNS) and two sham settings during a passive task while measuring pupillary response.
- Trial name
- NCT05386563
- Testing
- Transcutaneous Auricular Vagal Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Healthy
Transcutaneous Vagus Nerve Stimulation (taVNS) Dosage Study 1
The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS).
- Trial name
- NCT06381102
- Testing
- transcutaneous auricular vagus nerve stimulation 30/30, transcutaneous auricular vagus nerve stimulation 10/10
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Miami
Healthy
Effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Plasma Insulin Levels
The vagus or vagal nerve is a nerve that sends signals from the brain to other parts of the body to control involuntary functionm, including stomach function, and it is important to the regulation of insulin, C-peptide, and…
- Trial name
- TaVNS (NCT06597149)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Indiana University
Autonomic Nervous System Imbalance
Vagus Nerve Stimulation for Autonomic Nervous System Activity
There are no generally accepted values for transcutaneous vagus nerve stimulation (taVSS application parameters (amplitude, frequency, intensity, duration, side) yet, therefore there are heterogeneous applications in studies.
- Trial name
- NCT05906940
- Testing
- Transcutaneous Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Epilepsy
Transcutaneous Auricular Vagus Nerve Stimulation for Pediatric Epilepsy
The purpose of this study is to determine whether transcutaneous auricular vagus nerve stimulation as a complementary therapy is effective in the treatment of pediatric epilepsy.
- Trial name
- NCT02004340
- Testing
- ear vagus nerve stimulator
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- China Academy of Chinese Medical Sciences
Healthy Subjects
ABVN Phase 1 - Vagal Maneuvers
The vagus nerve is a nerve that controls many bodily functions, including stomach function. Investigators hope to be able to measure the activity of the vagus nerve when it is stimulated through simple physical techniques.
- Trial name
- ABVN1 (NCT07881276)
- Testing
- Vagal Maneuvers, Multi-Electrode Array (MEA) Recording
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Indiana University
Autonomic Nervous System (ANS) Functioning and Mood State, Heart Rate Variability (HRV)
taVNS During Multi-site HRV Measurement: Reliability & Agreement Study
This study examines the reliability and agreement of autonomic nervous system measurements obtained from different anatomical sites during transcutaneous auricular vagus nerve stimulation (taVNS).
- Conditions
- Autonomic Nervous System (ANS) Functioning and Mood State, Heart Rate Variability (HRV), Blood Pressure Monitoring, Transcutaneous Electric Nerve Stimulation
- Trial name
- taVNS-HRV (NCT07548723)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK