Clinical trials: Autism
Chromosome 22q11.2 Deletion Syndrome
Genetics and Psychopathology in the 22q11 Deletion Syndrome
The purposes of this study are to: 1. study the nature and longitudinal course of psychiatric symptoms in children with the 22q11.2 deletion syndrome and 2. identify genes that contribute to the occurrence of these symptoms.
- Trial name
- NCT00161109
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Autism Spectrum Disorder, Autism
Exome Sequencing in Autistic Spectrum Disorder
Background: Research into the genetic causes of autism spectrum disorder (ASD) involves studies of the DNA of children with autism.
- Conditions
- Autism Spectrum Disorder, Autism, Autistic Disorder
- Trial name
- NCT01059201
- Where
- 3 sites in United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder
Effect of PECS in Improving Oral Hygiene Status Among Preschool Chidren
Background: Oral health is an important part of overall health of the children and precisely it is additionally imperative for children who need out of the ordinary or special health care.
- Trial name
- PECS (NCT06588062)
- Testing
- Picture Exchange Communication System (PECS)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Autism Spectrum Disorder
Neurotherapy to Promote Emotion Recognition in Autism
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder, more prevalent than previously thought and heterogeneous in expression, though uniformly characterized by severe social disability.
- Trial name
- NCT03376373
- Testing
- neurofeedback
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Autism Spectrum Disorder, Autism
Investigation of Mechanisms of Action in Superpower Glass
The following study aims to understand the mechanism of action at work in a novel artificial intelligence (AI) tool that runs on Google Glass through an Android app to deliver social emotion cues to children with autism during…
- Trial name
- NCT04049981
- Testing
- Superpower Glass
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Child Behavior
Parents Resources for Decreasing the Incidence of Change Triggered Temper Outbursts
'PREDICTORS' (Parents Resources for Decreasing the Incidence of Change Triggered Temper Outbursts) aims to evaluate web-based training packages for caregivers of children who show frequent temper outbursts following changes to…
- Trial name
- PREDICTORS (NCT02567357)
- Testing
- Visual Scheduling, signalling change
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Autism Spectrum Disorder, Autism
Immersive Room for Visual Attention in Children With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by language delay, impaired social interactions, and repetitive behaviors.
- Trial name
- NCT05930873
- Testing
- Immersive room, stimuli in a paper format
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder, Healthy
Effects of Drugs on Responses to Brain and Emotional Processes
To study the effects of a psychostimulant on responses to affective touch in individuals with a range of autistic traits
- Trial name
- MAT (NCT04053036)
- Testing
- MDMA
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Caregiver Burden
10-Week Physical Activity Program for Mothers of Children With Developmental Disabilities
The purpose of this study is to determine the feasibility and acceptability of a 10-week supervised Physical Activity program for mothers of children with developmental disabilities.
- Trial name
- NCT07182071
- Testing
- Physical Activity Program, Waitlist for Physical Activity Program
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Autism Spectrum Disorder (ASD)
Non-Helium Magnetoencephalography in Autism Spectrum Disorder
The goal of this observational study is to learn how brain activity in children with autism spectrum disorder (ASD) differs from typical developing children using magnetoencephalography (MEG).
- Trial name
- NCT07064967
- Testing
- Magnetoencephalography
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Autism Spectrum Disorder (ASD)
How Trunk Control Links Autism Severity to Functional Exercise Capacity in Children With ASD
The goal of this observational study is to learn if trunk control (the ability to balance and stabilize the upper body while sitting or moving) links autism severity to functional exercise capacity in children aged 4-12 years…
- Trial name
- NCT07634107
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Mehak Naeem
Autism Spectrum Disorder (ASD
Exploring the Physiological Mechanisms of Austism Through Organoids
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder affecting approximately 1% of the population, characterized by difficulties with social interaction and communication.
- Trial name
- EXPECT HYPE (NCT07494331)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Nonverbal Communication
Exploring Predictors of Response to a Peer-Mediated Intervention for Preschoolers With ASD
This study will examine what child variables (i.e., social attention and peer interest) predict communication gains in response to a peer-mediated intervention for 40 minimally-verbal preschool children with ASD and 80 peers.
- Trial name
- NCT05277103
- Testing
- Exploring predictors of response to a peer-mediated communication intervention for minimally verbal preschoolers with ASD
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Autism Spectrum Disorders
Structural Connectivity as Imaging Endophenotypes of Autism Spectrum Disorders
Autism spectrum disorders (ASD) is a highly hereditary neuropsychiatric disorder. In children and adolescents worldwide, the prevalence of ASD is estimated at 0.6%.
- Trial name
- NCT01513629
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Focus Group Study of UK Nursing and Midwifery Council Registrant Nursing Associates Working in Mental Health, Learning Disability and Autism Services
MHLDA Nursing Associates Focus Group
Focus group study of UK Nursing and Midwifery Council registrant nursing associates working in mental health, learning disability and autism services
- Trial name
- NCT07009431
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Royal Cornwall Hospitals Trust
Autism Spectrum Disorder, Autism
Feasibility of Mobile Game System for Potential Treatment of Developmental Delays
The investigators will test the feasibility and preliminary efficacy of a Mobile game system meant to generate valuable data for measuring progress and building novel artificial intelligence models while delivering impactful…
- Trial name
- NCT04909710
- Testing
- Mobile Game System for Potential Treatment of Developmental Delays
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorder, Motor Activity
rTMS to Improve Motor Function in Autism
In the current project, investigators have two main goals: i) Testing whether an excessive plasticity, i.e. hyperplasticity in the motor cortex underlies motor function difficulties in autistic adults, and ii) Using repetitive…
- Trial name
- (AMBLE Autism) (NCT06497920)
- Testing
- Active rTMS to the motor cortex
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Autism Spectrum Disorder
Motor Intervention, Motor Skills, and Dual Task in ASD
This study is designed to understand whether a structured movement (motor) program can help improve movement skills and daily functioning in young children with autism spectrum disorder (ASD).
- Trial name
- NCT07386106
- Testing
- Motor Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Autism
TMS Measures of Plasticity and Excitatory/Inhibitory Ratio as Biomarkers: R-baclofen Effects in Normal Volunteers
Our overall objective is to apply Transcranial Magnetic Stimulation (TMS) to develop measures of human synaptic plasticity and of brain excitatory:inhibitory ratio (E:I ratio), which we propose as novel biomarkers and outcome…
- Trial name
- NCT01172509
- Testing
- R-baclofen
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Gonzalez-Heydrich, Joseph, M.D.
Autism Spectrum Disorder
Cognitive Support Technology for Postsecondary Students With Autism Spectrum Disorder
This study will fill important knowledge gaps in the availability of best practices that use innovative methods to integrate the cognitive and vocational needs of students with Autism Spectrum Disorder (ASD) who will be…
- Trial name
- NCT04980963
- Testing
- Cognitive Support Technology (CST)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kent State University