Clinical trials: Autism
Autism Spectrum Disorder
Measuring Brain Inflammation in Autism
Autism spectrum disorders (ASD) are highly disabling, persistent neurodevelopmental disorders. There are no available treatments for core symptoms of ASD or biologically-based clinical biomarkers.
- Trial name
- NCT03117530
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Interactive Mirroring Games wIth sOcial Robot (IOGIOCO) and Robotic System Adapted Into a Clinical Scale (RISCALE)
Background: The importance of early intervention in Autism Spectrum Disorders (ASD) has been widely demonstrated, and developmental trajectories in ASD highlight the importance of nonverbal communication, such as intransitive…
- Trial name
- RISCALE (NCT06855446)
- Testing
- Intervention with social robot NAO, Treatment as usual
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Autistic Disorder
Building Social Skills With Interdisciplinary Process Drama in ASD
This is a one group pre-post feasibility study of an interdisciplinary (theatre, Occupational Therapy (OT) and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT03536351
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Utah
Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP)
French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism Spectrum Disorders, and Healthy Controls
The goal of this study is to learn whether people living with severe psychiatric disorders can be grouped into more homogeneous subgroups, across usual diagnostic categories, based on two key dimensions: social withdrawal and…
- Conditions
- Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP), Bipolar Disorder (BD), Major Depressive Disorder (MDD
- Trial name
- FRENCH-MINDS (NCT07881016)
- Testing
- 3T Brain MRI, Biological Sampling, Clinical, Cognitive and Digital Assessments
- Where
- 17 sites in France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fondation FondaMental
Autism, Autism Spectrum Disorder
Cerebellum and Autism: Regional Specialization for Social and Executive Functions
The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.
- Trial name
- NCT05396352
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University
Autism
Parent Language Intervention for Autism
Improving social communication outcomes for children with autism spectrum disorders (ASD) has important public health implications.
- Trial name
- NCT02632773
- Testing
- Responsive Intervention, Directive Intervention
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autism, Stress
5Minutes4Myself: A Wellness Program for Caregivers
This research study refines a wellness program designed for caregivers of autistic children called 5Minutes4Myself and further investigates its feasibility.
- Conditions
- Autism, Stress, Autism Spectrum Disorder
- Trial name
- NCT03771001
- Testing
- Motivational Interviewing coaching and habit-building app
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Physical Activity, Motor Skills Development
Feasibility and Acceptability of a Co-produced Intervention to Improve Physical Activity and Motor Competence Amongst Children With Intellectual Disabilities and/or Autism Spectrum Disorder: Movement Matters
The goal of this observational study is to find out whether an intervention designed to improve physical activity levels and movement skills is practical and acceptable for children aged 7-11 years with intellectual disabilities…
- Trial name
- MM (NCT07456514)
- Testing
- Movement Matters
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Autistic Disorder
A Trial to Assess the Efficacy and Safety of Medical Grade Cannabis in Children Diagnosed With Autism Spectrum Disorder
This single center, double-blinded, randomized, placebo-controlled crossover trial will assess the efficacy and safety of extraction of cannabis flowers dissolved in olive oil (30% CBD and 1.5% Δ9-THC) vs.
- Trial name
- NCT05413187
- Testing
- Medical Grade Cannabis oil
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- TO Pharmaceuticals
Autism Spectrum Disorder
A Collaborative Public/Private Employment Training and Placement Model ASD Transition Age Youth With Autism Spectrum Disorder (ASD)
The aim of the research project is to conduct evidence-based research on a nationally known vocational rehabilitation (VR) service model (Project Search) for individuals with Autism Spectrum Disorders (ASD).
- Trial name
- ProjSEARCH1 (NCT02360332)
- Testing
- Project SEARCH plus ASD Supports
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Autism, Challenging Behavior
Testing a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health
The goal of this clinical trial is to test whether a smartphone-based data collection and feedback application ("Footsteps") improves the quality of behavioral data collected by one-to-one aides and leads to better youth mental…
- Conditions
- Autism, Challenging Behavior, ADHD, Oppositional Defiant Disorder
- Trial name
- Footsteps (NCT07042347)
- Testing
- Behavioral economics strategies, Electronic platform
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorder
The Therapeutic Effects of Intermittent Theta Burst Stimulation in Autism Spectrum Disorder
The investigator would like to investigate the impact of theta burst stimulation over right inferior frontal gyrus in autism spectrum disorder
- Trial name
- NCT04987749
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder
Effectiveness of the Care Coordination, Assessment, and Responsive Engagement Program for Transition-aged Adolescents (t-CARE) With ASD
An analysis of data for adolescents and young adults diagnosed with Autism Spectrum Disorders (ASDs) who are evaluated as part of the Care Coordination, Assessment, and Responsive Engagement for transition-aged adolescents…
- Trial name
- t-CARE (NCT03019952)
- Testing
- Care Coordination Visit
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Cognitive Function 1, Social
Social Cognition Assessment in Young Adults
The primary objective of this study is to determine the efficacy and feasibility of a battery of neuropsychological measures evaluating social cognition and behavior in young adults diagnosed with schizophrenia, autism spectrum…
- Trial name
- NCT02922400
- Testing
- Social Cognition Assessment and Training
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Autism Spectrum Disorder, Autism
Achieving Steady Work Among Adults With Autism Through Specialized Employment Program
Individuals with autism spectrum disorder (ASD) have significantly higher levels of unemployment and underemployment compared to their typically developing peers and all other groups with neurodevelopmental disorders, even though…
- Trial name
- NCT04107064
- Testing
- NaW, NaW-DS
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lawrence Fung
Autism Spectrum Disorder
Assessing the Effectiveness of Reciprocal Imitation Teaching in Part C Early Intervention Settings (Sprout Study)
Despite strong consensus that early, specialized intervention for children with Autism Spectrum Disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05425277
- Testing
- Reciprocal Intervention Teaching (RIT), Daily Routines
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hearing Loss, ASD
Diagnostic Instruments for Autism in Deaf Children Study
The trial is in three stages and will translate and validate screening and assessment instruments for use with deaf children. The first stage is modifying the screening and assessment instruments (ADI-R and ADOS-2) for use with…
- Trial name
- DIADS (NCT01932515)
- Testing
- A revised screening instrument for use in Deaf children
- Where
- United Kingdom
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Leeds and York Partnership NHS Foundation Trust
Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD)
Exploring Eye Vergence Markers ADHD) and ASD
The investigators study aims to evaluate the utility of eye vergence, an eye-tracking measure, as an indicator of visuo-spatial attention in children aged 4-17 years and adults, using computer-based eye-tracking tasks.
- Trial name
- NCT06885060
- Testing
- BGaze ADHD Diagnostic Test, Oddball/Alerting Computer Task, Facical Emotion Computer Task
- Where
- 3 sites in Spain, United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Elizabeth Kilbey
Autism Spectrum Disorders
Virtual Reality Social Cognition Training for Adults With Autism Spectrum Disorders
The purpose of this study is to predict and explain on the basis of brain function and structure the behavioral and brain effects of an evidence-based intervention for adults with high-functioning autism, Virtual Reality-Social…
- Trial name
- NCT02139514
- Testing
- Virtual Reality Social Cognition Training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism Spectrum Disorder
Shifting Brain Excitation-Inhibition Balance in Autism Spectrum Disorder
This study investigates brain response to single acute dose of cannabidiol, cannabidivarin, and placebo in healthy men with and without autism spectrum disorder
- Trial name
- NCT03537950
- Testing
- PLC, CBD, CBDV
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- King's College London