Clinical trials: Autism
Autism Spectrum Disorder
Trial of Autism Parent Navigator Program
To address the dual needs of parents for support in navigating Autistic Spectrum Disorder (ASD) services and maintaining positive family functioning, the investigators propose to test Autism Parent Navigators (APN), an innovative…
- Trial name
- APN (NCT04744428)
- Testing
- Autism Parent Navigators, Peer mentoring
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Penn State University
Modified Atkins Diet, Autism Spectrum Disorder
Efficacy of MAD as add-on Therapy in Comparison With Standard of Care in Children With ASD
In general ketogenic diet is a recognized as an efficient non pharmacological treatment for children with refractory epilepsy. However, in the last decade, it has been tried for many neurological disorders in children including…
- Conditions
- Modified Atkins Diet, Autism Spectrum Disorder, Standard of Care
- Trial name
- NCT06315465
- Testing
- Modified Atkin's Diet with standard of care, Standard of Care
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Autism, Developmental Disabilities
Magnetic Resonance Imaging in Children and Adolescents With Autism and Multiple Complex Developmental Disorders
This study aims to investigate the overlap and differences between autism and MCDD as neuropsychiatric childhood disorders. MRI scans are acquired from subjects with autism, subjects with a diagnosis of MCDD and typically…
- Trial name
- NCT00161135
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Autism Spectrum Disorder, Sleep Disorder
Effect of Snoezelen-Based Occupational Therapy Intervention on Sleep and Behavior Problems in Infant at Risk of Autism
Objective: Sleep and behavioral problems are common in infants at risk of autism. This study aims to examine the effect of Snoezelen-Based Occupational Therapy intervention on sleep and behavioral problems in infants at risk of…
- Conditions
- Autism Spectrum Disorder, Sleep Disorder, Behavior Problem
- Trial name
- NCT06164210
- Testing
- Snoezelen-Based Occupational Therapy Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ankara University
Autism Spectrum Disorder (ASD
Monitoring Daily Mobility in Children With Autism
Children with autism spectrum disorder (ASD) often show motor abnormalities and sleep disturbances that affect behavior, learning, and family quality of life.
- Trial name
- SIMBA (NCT07519369)
- Testing
- placement of a wearable wrist sensor
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Autism Spectrum Disorder
Improving ToM in Children With ASD Through VPT Training: Behavioral and fNIRS Study
This study aims to employ a longitudinal tracking research to investigate the effects of a visual perspective taking intervention on the development of theory of mind in children with autism.
- Trial name
- NCT06196060
- Testing
- Visual perspective taking training, Block building training, Thought-bubble training
- Where
- 3 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing Normal University
Autism Spectrum Disorder
The Relationship Between Parents' Fatigue and Quality of Life
By comparing them to a healthy control group, this study aims to investigate the relationship between the participation of children with autism spectrum disorder (ASD) in home, school, and community environments and their…
- Trial name
- NCT05422261
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Speech, Autism Spectrum Disorder (ASD)
Research on Speech Development Trajectories and Predictive Models in Children With Autism Spectrum Disorder
Recent studies indicate that children with ASD have a significantly higher risk of co-occurring speech sound disorders than typically developing children.
- Trial name
- NCT07472829
- Testing
- Approaches to ASD social intervention
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Autism Spectrum Disorder
Telehealth Autism Assessment for Adults
The study aims to investigate the reliability and validity of an adapted Autism Spectrum Disorder assessment measure for use in a telehealth visit.
- Trial name
- NCT04766970
- Testing
- ADOS-2 Module 4, Adapted Telehealth ADOS-2 Module 4
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Autism, Sociocommunicative Challenges
Improving Autism Program Quality in Special Education Units: The Use of an APERS-based Model to Support Student Learning and Participation
This study assesses the effect of using the Autism Program Environment Rating Scale (APERS) as a tool for providing feedback, in-service training, and coaching to school staff in order to improve program quality in special…
- Trial name
- NCT07830160
- Testing
- APERS+
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Tuberous Sclerosis, Autism Disorder
Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)
The purpose of this study is to characterize the developmental phenotype of ASD and ID and to identify biomarkers using advanced MRI methodology and electrophysiological biomarkers of synaptic function and connectivity predictive…
- Conditions
- Tuberous Sclerosis, Autism Disorder, Intellectual Disability
- Trial name
- NCT02461459
- Where
- 6 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Autism, Extra-axial Fluid
Transcranial Ultrasonography Using Linear 2D Imaging of the Brain
This study will use linear 2D ultrasound imaging to look at the brain of individuals diagnosed with autism and their siblings. This is called transcranial ultrasound (TUS).
- Trial name
- NCT01980186
- Testing
- TUS transcranial 2D ultrasound
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brain Treatment Center
Autism Spectrum Disorder, Autism
Exome Sequencing in Autistic Spectrum Disorder
Background: Research into the genetic causes of autism spectrum disorder (ASD) involves studies of the DNA of children with autism.
- Conditions
- Autism Spectrum Disorder, Autism, Autistic Disorder
- Trial name
- NCT01059201
- Where
- 3 sites in United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorders
Emotional and Change-related Attention in Autism
Several studies seem to indicate that emotional attention and change-related attention are impaired in ASD. The goal of this study is to identify the relationships between those two types of automatic attention in visual and…
- Trial name
- AUTATTEN (NCT02160119)
- Testing
- MRI-based techniques, EEG
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism Spectrum Disorder
REGulatory T Cells in Autism Induced by Maternal Immune Activation
Autism Spectrum Disorders (ASD) represent a heterogeneous clinical entity of neurodevelopmental disorders affecting around 1% of the general population (Lord et al. 2020).
- Trial name
- REGAIN (NCT06169111)
- Testing
- REGulatory T cells in Autism induced by maternal Immune activation
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder (ASD)
Choice Switching and Autism
The study aims to replicate and clarify a recently observed phenomenon whereby individuals with Autism Spectrum Disorder (ASD) switch between options in a repeated task to a greater extent than healthy controls do.
- Trial name
- NCT04631432
- Testing
- Pre-screening, Task session
- Where
- Israel
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Technion, Israel Institute of Technology
Autism Spectrum Disorder, Obesity, Childhood
Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
The objective of this proposed study is to collect initial efficacy data on a telehealth parent-based behavioral program for children with autism and overweight or obesity (PBT-A), compared with health education (HE).
- Conditions
- Autism Spectrum Disorder, Obesity, Childhood, Autism
- Trial name
- FRESH-A (NCT05741840)
- Testing
- PBT-A, Health Education (HE)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Mindfulness
Mindfulness Intervention for Parents of Children With ASD
This study aims to develop a smartphone app based on mindfulness-based interventions and test its effectiveness in parents of children with ASD. This study aims: 1.
- Trial name
- MAPASD (NCT05746468)
- Testing
- Ecological assessment and intervention, Audio-based Mindfulness intervention
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder
Validation of the Girls Questionnaire for Autism Spectrum Condition in French Langage
Autism spectrum disorders (ASD) are currently diagnosed at a rate of approximately 3 males per 1 female, while evidence suggests the rate may be 1.8 males per 1.2 females.
- Trial name
- fGQ-ASC (NCT06280521)
- Testing
- fGQ-ASC
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Autism Spectrum Disorder
Cannabidiol (CBD) in Adults With ASD
There are no FDA approved treatments for use in adults with autism spectrum disorder (ASD), many of whom have distressing anxiety, mood disturbances, sleep problems, and agitation.
- Trial name
- NCT05015439
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University