Clinical trials: Autism
Phelan-McDermid Syndrome, Autism Spectrum Disorder
Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome
The purpose of this study is to comprehensively characterize PMS using standardized medical, cognitive, and behavioral measures and to track the natural history of the syndrome using repeated longitudinal assessments.
- Conditions
- Phelan-McDermid Syndrome, Autism Spectrum Disorder, Intellectual Disability
- Trial name
- NCT02461420
- Where
- 5 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Parents, Stress
Telehealth Mindfulness-Based Music and Songwriting for Parents of Children With Intellectual/Developmental Disabilities
This is a pilot study of the feasibility and potential impact of a Mindfulness-Based Music and Songwriting program (delivered via telehealth) on stress and well-being in parents/caregivers of children with intellectual or…
- Conditions
- Parents, Stress, Developmental Disability, Intellectual Disability
- Trial name
- NCT04962659
- Testing
- Mindfulness-Based Music and Songwriting
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Autism Spectrum Disorder
Structured Sensory-Based Occupational Therapy in Children With Autism
This controlled clinical study will investigate the effects of a 12-week structured sensory-based occupational therapy intervention on occupational performance, sensory processing, gross motor development, and eating behaviors in…
- Trial name
- NCT07789704
- Testing
- Structured Sensory-Based Occupational Therapy, Individualized Home Activity Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emre DANSUK
Autism, Stress
5Minutes4Myself: A Wellness Program for Caregivers
This research study refines a wellness program designed for caregivers of autistic children called 5Minutes4Myself and further investigates its feasibility.
- Conditions
- Autism, Stress, Autism Spectrum Disorder
- Trial name
- NCT03771001
- Testing
- Motivational Interviewing coaching and habit-building app
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Autism Spectrum Disorder
REward SYSTem in Autism Spectrum Disorder and Addictive Disorder
An MRI Study in Subjects with Autism Spectrum Disorder and Subjects with Food Addictive Disorder compared to healthy volunteers.
- Trial name
- RESYSTAA (NCT05391113)
- Testing
- MRI, EEG
- Where
- 3 sites in France
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autism, Autism Disorder
Role of the Gut Vascular Barrier and Microbiota in Autism Spectrum Disorders
Recent research links gut microbiota alterations to Autism Spectrum Disorders (ASD), a neurobiological condition with multifactorial bases.
- Conditions
- Autism, Autism Disorder, Autism Spectrum Disorder (ASD)
- Trial name
- DSA/GVB (NCT07450443)
- Testing
- PostbiotiX Comfort®, Control
- Where
- 2 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Autism Spectrum Disorder
Study of the Genetic Factors Involved in Autism and Related Disorders
The main objective of the study is to define, for Autism Spectrum Disorder, the extent of genetic variation in synaptic pathways that may be targeted for therapeutic development.
- Trial name
- Gene&autism (NCT04727489)
- Testing
- DNA from subjects will be stored in the biobank of our study.
- Where
- 6 sites in France
- Volunteers
- 3,800 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism Spectrum Disorder
Emergence of Generative Language
The purpose of this study is to investigate the effects of several applied behavior teaching procedures on the use of multi-word utterances by children with autism.
- Trial name
- NCT02555241
- Testing
- Mand Training, Matrix, Stimulus Equivalence Training
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Emory University
Autism Spectrum Disorder
Real and Virtual Environments in Autism Spectrum Disorder
Individuals with Autism Spectrum Disorder (ASD) are known to have difficulty with socio-communicative functioning and restricted or repetitive behaviors or interests, and there is considerable evidence that the majority also…
- Trial name
- NCT03254992
- Testing
- ASD - Abstract task, ASD - Tangible task, TD - Abstract task
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Autism Spectrum Disorder
Autologous BMMNCs Combined With Educational Intervention for ASD
The purpose of this study is to evaluate the safety and effectiveness of autologous bone marrow mononuclear cell infusion combined with educational intervention for children with autism spectrum disorder (ASD).
- Trial name
- NCT05307536
- Testing
- Autologous BMMNCs transplantation and educational intervention, Educational intervention
- Where
- Vietnam
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Autism
Autism in Adult Patients and the Effects on Caregivers
Background: The number of adults with autism is expected to rise significantly in the near future, due to two main reasons: First, a dramatic increase in the estimates of the prevalence of autism starting in the mid 1980s…
- Trial name
- NCT00367107
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Autistic Disorder
Social Skills in Children With ASD and Process Drama
This is a one-group, pre-post feasibility study of an intensive, interdisciplinary (theatre, Occupational Therapy (OT), and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT02850666
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Utah
Autistic Disorder
Associative Memory in Adults With an Autism Spectrum Disorder
The objective of this multidisciplinary project is to explore the deficit of associative memory in ASD (Autistic Spectrum Disorder) that could result from abnormal brain connectivity.
- Trial name
- MEM-T2A (NCT02279680)
- Testing
- Electroencephalography, Neuropsychological assesments
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Parkinson Disease, Huntington Disease
A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions
Measurement of metabotropic glutamate receptor type 5 (mGluR5) binding capacity in the brain, may be a valuable tool in the early detection, understanding, or evaluation of Parkinson disease (PD), Huntington disease (HD), Fragile…
- Conditions
- Parkinson Disease, Huntington Disease, Autistic Spectrum Disorders, Fragile X Syndrome
- Trial name
- FPEB (NCT00870974)
- Testing
- [18F]FPEB
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Autism Spectrum Disorder
The Effect of Mindfulness-Based Self-Compassion Education Given to Parents of Children With Autism Spectrum Disorder
Autistic Spectrum Disorder (ASD) is an important public health problem in our country as well as all over the world. The physical, psychological, social and economic problems and mood disorders experienced by the parents of these…
- Trial name
- NCT05693662
- Testing
- Session 1, Session 2, Session 3
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Autism Spectrum Disorder
Social Cognitive Development in Young Children With Autism
Through the development of a novel treatment targeting core Autism Spectrum Disorder (ASD) social deficits and studying the efficacy of this intervention, the investigators hope to provide a means for children with ASD to more…
- Trial name
- NCT01425918
- Testing
- Social Enhancement Intervention, Parent Education
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism Spectrum Disorder
CPI Training for Parents of Children With ASD
The purpose of this 24-week study is to determine whether the "Parent-based Crisis Prevention Institute (CPI) physical management training program" (i.e., P-CPI) is effective in increasing self-efficacy in parents of children…
- Trial name
- NCT03537261
- Testing
- Parent-based Crisis Prevention Institute (CPI) physical management training program (P-CPI)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Fragile X Syndrome
Speech-in-noise Perception in Autism and Fragile X
The goal of this study is to identify which brain regions are active during speech-in-noise perception, as well as how those regions interact.
- Trial name
- NCT06088589
- Testing
- Mismatch negativity
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder (ASD), Joint Attention Impairment
Social Attention in ASD and TD Children
To examine whether the spatiotemporal organization of gaze strategies differs between children with autism spectrum disorder (ASD) and typically developing (TD) children during a staged joint attention interaction, and to…
- Trial name
- NCT07583615
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Autism Spectrum Disorder
Modulation of the Brain Excitatory/Inhibitory (E/I) Balance in Autism Spectrum Disorder (ASD)
This study investigates the brain response to a single acute dose of Arbaclofen, the R-enantiomer of the GABA-B agonist Baclofen, compared to a single dose of placebo in healthy men with and without autism spectrum disorder.
- Trial name
- NCT03594552
- Testing
- Arbaclofen_15, Arbaclofen_30
- Where
- United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- King's College London