Clinical trials: Autism, completed
Autism, Autism Spectrum Disorder
hCT-MSCs for Children With Autism Spectrum Disorder (ASD)
The purpose of this Phase 1 study is to determine the safety of one, two, and three intravenous infusions of human umbilical cord tissue-derived mesenchymal stromal cells (hCT-MSC), administered every two months, in children with…
- Conditions
- Autism, Autism Spectrum Disorder, ASD
- Trial name
- hCT-MSCs (NCT03099239)
- Testing
- hCT-MSC infusion
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Joanne Kurtzberg, MD
Asperger's Disorder, Mental Retardation
Cognitive Neuroscience of Autism Spectrum Disorders
Background: Autism spectrum disorders (ASDs) are a group of developmental disorders that affect communication, social interaction, and behavior.
- Conditions
- Asperger's Disorder, Mental Retardation, Children, Adult
- Trial name
- NCT01031407
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- National Institute of Mental Health (NIMH)
PTEN Hamartoma Tumor Syndrome
Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients
The purpose of this study is to develop a survey completed by parents, caregivers, or other informants that evaluates several important domains of functioning relevant to individuals with neurodevelopmental disorders, including…
- Trial name
- NCT05671107
- Testing
- NET
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 300 people
- Sponsor
- John Carroll University
Autism, Food Allergies
Treatment of Autistic Children Using NAET Procedures
1. Purpose of this study is to determine whether NAET procedures are effective in the treatment of children with allergy-related autism spectrum disorders in restoring their verbal and nonverbal communication. 2.
- Trial name
- NCT00277407
- Testing
- NAET with acupressure and/or chiropractic procedures
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Nambudripad's Allergy Research Foundation
Autism Spectrum Disorder
Pediatric Massage for Children With Autism Spectrum Disorder
This study was designed as a randomized controlled clinical trial of pediatric massage for children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04220086
- Testing
- Pediatric massage therapy, Usual care, No intervention
- Where
- 2 sites in China
- Volunteers
- 78 people
- Sponsor
- The University of Hong Kong
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT04111874
- Testing
- Cognitive Behavioral Teletherapy LTA, Cognitive Behavioral Teletherapy STA
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder, Neurofibromatosis 1
From Molecules to Cognition: Inhibitory Mechanisms in ASD and NF1
This study aims to investigate synaptic physiology and behavioral inhibition in patients with NF1 and ASD and to answer whether inhibitory deficits at these levels are modulated by lovastatin.
- Trial name
- ASD/NF1inhib (NCT03826940)
- Testing
- Lovastatin 60 MG
- Where
- Portugal
- Volunteers
- 16 people
- Sponsor
- University of Coimbra
Autism Spectrum Disorder
Role of Folinic Acid in Improving the Adaptive Skills and Language Impairment in Children With Autism Spectrum Disorder
No such study has been conducted in Pakistan so the primary objective of this study was to determine the role of folinic acid in improving the speech and adaptive skills while secondary objective was improvement of stereotype…
- Trial name
- NCT05013164
- Testing
- Folinic Acid
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Autistic Youth, Nintendo Exergaming Group, No Intervention Control Group
COMPARING EFFECTS OF NINTENDO EXERGAMING TO A NO INTERVENTION CONTROL GROUP
This is a pilot randomized clinical trial to evaluate the feasibility and acceptability, and preliminary outcomes of delivering a Nintendo Switch exergaming (NE group) intervention in a group of autistic youth with autism…
- Trial name
- NCT07720427
- Testing
- Nintendo Switch Exergaming
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Delaware
Autism Spectrum Disorder
Comparison of DSM-IV-TR and DSM-5 for ASD
The study aim is to prospectively compare DSM-IV-TR and DSM-5 criteria for Autism Spectrum Disorder (ASD) in a sample of 250 children and adolescents who meet DSM-IV-TR criteria for ASD and 150 children and adolescents referred…
- Trial name
- NCT02296502
- Testing
- DSM
- Where
- 5 sites in United States
- Volunteers
- 439 people
- Sponsor
- University of Pittsburgh
Neurodevelopmental Disorders, Developmental Disabilities
Family Networks (FaNs) for Children With Developmental Disorders and Delays
Over 6% of children in Pakistan suffer from a developmental disorder (intellectual disability or Autistic spectrum disorder) and most receive no intervention.In an earlier proof of concept study, the investigators integrated…
- Trial name
- FaNs (NCT02792894)
- Testing
- Family networks program
- Where
- Pakistan
- Volunteers
- 540 people
- Sponsor
- Human Development Research Foundation, Pakistan
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
GroundsKeeper: A Qualitative Study of Applied Game-based Interactives in Special Education Programs
The purpose of this study is to examine the use of, and reaction to, one particular software application(GroundsKeeper) delivered on unique platform - Sifteo cubes (www.sifteo.com).
- Conditions
- Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Pervasive Developmental Disorder, Asperger's Disorder
- Trial name
- NCT01808066
- Testing
- Groundskeeper
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- CogCubed, Corp
Autistic Disorder
Sapropterin as a Treatment for Autistic Disorder
This study is intended to provide a definitive test of the hypothesis that elevating sapropterin (tetrahydrobiopterin, a cofactor for several key brain enzymes)concentrations in the CNS will result in measurable improvements in…
- Trial name
- NCT00850070
- Testing
- sapropterin
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- The Children's Health Council
Pregnancy, Autistic Disorder
Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children
The purpose of this research study is to screen for metabolic abnormalities that are maternal risk factors for having a child with autism.
- Conditions
- Pregnancy, Autistic Disorder, Folic Acid Deficiency
- Trial name
- NCT02674022
- Testing
- Prenatal supplement
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Fragile X Syndrome
Trial of Sertraline to Treat Children With Fragile X Syndrome
This study is a control trial of sertraline (Zoloft) in fragile X syndrome children aged 2 years to 5 years 8 months old. The trial is six months long, and each participant will receive a series of tests at both the beginning and…
- Trial name
- NCT01474746
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Randi J. Hagerman, MD
Autism Spectrum Disorder
Facing Your Fears in Schools: Implementing a CBT Program for Students With ASD or Other Special Learning Needs
The overall goal of the project is to develop a feasible, effective and sustainable school-based program to manage anxiety in elementary and middle school students with Autism Spectrum Disorder (ASD) and other special learning…
- Trial name
- FYF-SB (NCT03685474)
- Testing
- Facing Your Fears - School Based, Usual Care
- Where
- United States
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autism, Anorexia Nervosa
Neural Correlates of Autistic Individuals With Anorexia Nervosa
Masking is a behaviour or strategy used by many Autistic people to appear non-Autistic and blend in with a neurotypical society.
- Trial name
- NCT07098156
- Testing
- Single Research Visit 3T MRI Research Scan, Demographic and Behavioural Questionnaires
- Where
- 2 sites in United Kingdom
- Volunteers
- 29 people
- Sponsor
- University of Aberdeen
Autistic Spectrum Disorder, Constipation
Oral Administration of Polyethylene Glycol (PEG) for 6 Months in Chronically Constipated Autistic Children
Many autistic children suffer from chronic constipation. Gut mobilization was obtained administering polyethylene glycol (PEG) at the dose of 6.9 g/d once a day for 6 months in an open trial involving 21 chronically constipated…
- Trial name
- NCT05025553
- Testing
- Gut mobilization
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Messina
Autism Spectrum Disorder, Social Stories
Effect of Social Stories on Anesthesia Compliance in Children With Autism
Children with Autism Spectrum Disorder (ASD) frequently experience heightened anxiety and reduced cooperation during the perioperative period, which can complicate anesthesia induction and negatively affect procedural safety and…
- Trial name
- NCT07356895
- Testing
- Social Stories Group, Routine Preoperative Preparation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Autism, Autism Spectrum Disorders
Treatment of Sleep Disturbances in Young Children With Autism
This study will compare the efficacy of a behavioral parent training program (PT) aimed specifically at common sleep disturbances compared to parent education (PE) program focusing on general issues related to autism.
- Trial name
- NCT01322022
- Testing
- ParentTraining, Parent Education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh