Clinical trials: Autism
Autism Spectrum Disorder
Targeting Repetitive Behaviors in Autism Spectrum Disorder Via Transcranial Direct Current Stimulation
Repetitive behaviors (RBs) are a prevalent feature of Autism Spectrum Disorder (ASD). There are two groups of RBs: lower-order (e.g. motor stereotypies) and higher-order RBs (e.g.
- Trial name
- NCT06645587
- Testing
- Active HD-tDCS over pre-SMA, Active HD-tDCS over left DLPFC
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Autism Spectrum Disorder
Effects of Rhythmic Balance Auditory Vision Training And Strength Training With Autism Spectrum Disorder.
Autism, a complex neurodevelopmental disorder that is marked by limited interests, and challenges in communication and social interactions and problem includes difficulties in understanding and responding to social cues…
- Trial name
- NCT06308315
- Testing
- Rhythmic balance visual auditory exercise + Routine physical therapy, Strength Training + Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder, Autism
Using Serious Games to Improve Social Skills in Autism
The investigators will conduct a small-scale randomized control trial comparing the intervention game to an active control game, and will assess outcomes at multiple time points (pre-, post-, 6-month follow-up).
- Trial name
- SAGA (NCT03690661)
- Testing
- Intervention Video Game
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Penn State University
Autism Spectrum Disorder, Dexmedetomidine
Esketamine Combined With Dexmedetomidine Sedation in Head MRI Examination of Children With Autism Spectrum Disorder
Objective: To investigate the use of ketamine combined with dexmedetomidine for sedation in children with autism spectrum disorder, Methods:aged 2-6 years,, ASA grade I or II.
- Conditions
- Autism Spectrum Disorder, Dexmedetomidine, Esketamine, Sedation
- Trial name
- NCT06633315
- Testing
- low dos dexmedetomidine, high dos dexmedetomidine, dexmedetomidine and esketamine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Autism Spectrum Disorder
Investigating Social Competence in Youth With Autism
Our treatment, SENSE Theatre, combines several well-documented, effective behavioral strategies and theatre techniques. The proposed project will extend previous findings showing improving improvement in memory for faces.
- Trial name
- NCT03368001
- Testing
- SENSE Theatre, Tackling Teenage Together
- Where
- 3 sites in United States
- Volunteers
- 318 people
- Sponsor
- Vanderbilt University Medical Center
Autism, Parenting
The Effects of an Empowerment Program for Parents of Children With Autism
This study aims to evaluate the effectiveness of an empowerment program that includes both parent training and motivational interviewing for parents of children with autism, supporting their competence in the care of their…
- Conditions
- Autism, Parenting, Motivational Interviewing
- Trial name
- NCT06629974
- Testing
- Parental empowerment program
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Manisa Celal Bayar University
Autism Spectrum Disorder
Effect of Increasing Total Antioxidant Capacity in Autism Spectrum Disorder
This double-blind, randomized, controlled trial (RCT) has the aim to evaluating the effectiveness of increasing Total Antioxidant Capacity (TAC) as add-on intervention in two cohorts of patients with Autism Spectrum Disorder…
- Trial name
- TACASD (NCT06623227)
- Testing
- Vitamin E and C
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Rinvil Renaldi
Autism Spectrum Disorder, Speech
Thinking in Speech for Children With Autism
This study examines a cognitive therapy for autistic children, Thinking in Speech. Thinking in Speech helps children with autism independently cope with everyday events that cause stress, by developing their ability to use "inner…
- Trial name
- NCT05256095
- Testing
- Thinking in Speech
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder
Effect of Probiotic Compound K11T e K11TMax in ASD
The research is characterized as a randomized, double-blind clinical trial (phase III) in which administered the probiotic K11-T (with and without added amino acids, fatty acids and vitamins) to children between 3 and 11 years…
- Trial name
- ASD (NCT06382909)
- Testing
- Inflammatory level, Cognitive assessment, Pedagogical assessment
- Where
- 2 sites in Brazil
- Volunteers
- 505 people
- Sponsor
- Deivis de Oliveira guimaraes
Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders
Telepsychiatry in Children: Diagnostic Evaluation of Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder recognized as a major national cause in 2012. The French Autism Plan 2018-2022 emphasizes early diagnosis and intervention for better cognitive and behavioral…
- Trial name
- TELE-TSA (NCT06622395)
- Testing
- Remote diagnosys
- Where
- France
- Volunteers
- 137 people
- Sponsor
- Centre Hospitalier St Anne
Autism Spectrum Disorder, Anxiety
A Pilot Study of Buspirone for the Treatment of Anxiety in Youth with Autism Spectrum Disorders
The main objective of this exploratory 8-week pilot study is to evaluate the safety and efficacy of buspirone for the treatment of anxiety in youth (ages 6-17 years) with autism spectrum disorders.
- Trial name
- NCT03432065
- Testing
- Buspirone
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Gastrointestinal Dysfunction
ASC - Autism Study
The ASC - Autism Pilot Study is a single center randomized open dose titrating phase I clinical intervention pilot trial with the aim of investigating safety and treatment effect of an allogeneic adipose tissue derived…
- Conditions
- Autism Spectrum Disorder, Gastrointestinal Dysfunction, Leaky Gut Syndrome, Mesenchymal Stromal Cells
- Trial name
- NCT05602116
- Testing
- Adipose tissue derived mesenchymal stromal/stem cells (Cell2Cure®)
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Cell to Cure ApS
Autism Spectrum Disorder
JASPER Implementation in NFLD
This study will focus on examining the supports required to enable community Senior JASPER Trainers to support the training and development of junior interventionists throughout the province of Newfoundland and Labrador, Canada.
- Trial name
- NCT03205475
- Testing
- Alternate Coaching and Video Feedback Phase 1, Weekly Coaching in Phase 1, Weekly Coaching plus Intensive Refresher Course Phase 2
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Government of Newfoundland and Labrador
Autism Spectrum Disorder, Gastro-Intestinal Disorder
Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders
The investigators propose to investigate Microbiota Transfer Therapy (MTT) for treating patients with Autism-spectrum disorder with Gastrointestinal disorders (constipation, diarrhea, and/or abdominal pain).
- Conditions
- Autism Spectrum Disorder, Gastro-Intestinal Disorder, Constipation, Diarrhea
- Trial name
- NCT06503978
- Testing
- MTP-101P, Vancomycin, Miralax
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Gut-Brain-Axis Therapeutics Inc.
Autism Spectrum Disorder (ASD)
Impact of AAI Dogs on Performance and Behavior of Children with Autism
Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental disorder usually diagnosed in early childhood. Children with ASD exhibit social communication and interaction problems, which may cause deficits in social-emotional…
- Trial name
- AAI (NCT06609122)
- Testing
- Animal Assisted Intervention
- Where
- Hong Kong
- Volunteers
- 66 people
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder
Partners in School: Promoting Continuity Across Home and School
Partners in School is a collection of implementation strategies (e.g., communication training, problem-solving consultation) to help parents/primary caregivers and teachers of children with autism spectrum disorder implement the…
- Trial name
- NCT05154981
- Testing
- Education communication skills (ECS) training, Partners in School
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Autism Spectrum Disorder (ASD, Parental Behaviors
Effectiveness of Video-feedback for Positive Parenting with Children At Risk of ASD
Improving parent-child interactions benefits child development and parents' perception of their competencies for childrearing and support for child learning and development, which in turns positively impacts on parental emotional…
- Trial name
- VIFEPOPA (NCT06604988)
- Testing
- Video-feedback intervention to promote positive parenting
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Autism, ASD
Fronto-temporal tDCS Mproves Fluency & Empathy in ASD Kids
Interventional, prospective, randomized, double-blind, placebo-controlled and parallel assignment study, in which patients with Autism Spectrum Disorder (ASD) are two types of intervention by transcranial random noise stimulation…
- Trial name
- tDCS25112013 (NCT02004236)
- Testing
- tRNS Fronto-temporal cortex, tRNS over fusiform temporal cortex
- Where
- 2 sites in United Kingdom
- Volunteers
- 225 people
- Sponsor
- Spanish Foundation for Neurometrics Development
Autism Spectrum Disorder, Sleep Disturbance
Telehealth Delivery of Treatment for Sleep Disturbances in Young Children With Autism Spectrum Disorder
Study Design: Ninety children with Autism Spectrum Disorder (ASD), between the ages of 2 to less than 7 years, and their parents will be recruited for this 10 week randomized clinical trial.
- Trial name
- NCT03668873
- Testing
- Sleep Parent Training, Sleep Parent Education
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- The Cleveland Clinic
Autism, Autism Spectrum Disorder
A Lead-in Study Evaluating Efficacy of GuessWhat Mobile App Therapy for Children With Autism
The following study aims to assess the efficacy, safety data, and best outcome measurements of the mobile game platform, GuessWhat, in delivering behavioral therapy to children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04739982
- Testing
- GuessWhat Mobile App
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Stanford University