Clinical trials: Autism, completed
Autistic Disorder
Living in a Precarious Situation With an Autistic Child: What Are the Issues at Stake for Support in Care
Study the specificities of families in a precarious situation with a child with autism spectrum disorders (ASD) in terms of housing, in order to better support them in the various social spaces and improve collaboration between…
- Trial name
- HaSPrEA (NCT04820998)
- Testing
- Families, professionals
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Autism, Autism Spectrum Disorder
First CRUSH: Piloting the Preliminary Feasibility and Acceptability of the Competence in Romance and Understanding Sexual Health (CRUSH) Curriculum
The goal of this clinical trial is to learn about the feasibility and acceptability of a behavioral intervention in designed to provide sexual education and improve the behavioral skills of autistic adults for intimate…
- Trial name
- NCT05910658
- Testing
- Competence in Romance and Understanding Sexual Health (CRUSH)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston Children's Hospital
Autism, Autism Spectrum Disorder
hCT-MSC in Children With Autism Spectrum Disorder
The purpose of this Phase II study is to determine the efficacy of human umbilical cord tissue-derived mesenchymal stromal cells (hCT-MSC) for improving social communication abilities in children with autism spectrum disorder…
- Trial name
- IMPACT (NCT04089579)
- Testing
- Cord Tissue Mesenchymal Stromal Cells
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Joanne Kurtzberg, MD
Fragile X Syndrome
Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome
The Fragile X syndrome (FXS) was first described by Dr. Martin and Dr. Bell in 1943, in families with several patients affected by sex-linked mental disability.
- Trial name
- SXF-TRA152 (NCT01329770)
- Testing
- Ascorbic Acid (Vitamin C) and Alpha-tocopherol (Vitamin E)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Yolanda de Diego Otero
Autism
Secretin for the Treatment of Autism
Many drugs used to treat autism target specific symptoms, such as hyperactivity and aggressiveness. Few drugs target the core autistic symptoms of impaired social interaction and communication.
- Trial name
- NCT00065962
- Testing
- secretin, synthetic porcine, secretin, biologically derived porcine
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder, Autism
A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism
The purpose of this study is to examine the effectiveness of pivotal response training (PRT) in an intensive center-based environment to treat social communication deficits in children with autism spectrum disorder (ASD).
- Trial name
- PRT-C (NCT03778827)
- Testing
- Intensive Center-Based Pivotal Response Treatment (PRT-C)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Autism Biomarker Consortium for Clinical Trials
This is a multicenter longitudinal study that aims to identify, develop and validate a set of measures that can be used as stratification biomarkers and/or sensitive and reliable objective measures of social impairment in autism…
- Trial name
- ABC-CT (NCT02996669)
- Where
- United States
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism
Psychological and Quality of Life Impact of Brain in Hand
A prospective cohort mixed study using both qualitative and quantitative elements. The quantitative component will involve tracking outcomes at baseline and at twelve weeks, using Health of the Nation Outcome Scale for People…
- Trial name
- BraininHand (NCT05468541)
- Where
- United Kingdom
- Volunteers
- 101 people
- Sponsor
- Cornwall Partnership NHS Foundation Trust
Autism Spectrum Disorder
Gaming Open Library for Intervention in Autism at Home (GOLIAH /MICHELANGELO)
To meet the required intensive intervention hour for treating children with autism spectrum disorder (ASD), the investigators developed an automated serious gaming platform (11 games) to deliver intensive intervention at home…
- Trial name
- MICHELANGELO (NCT02560415)
- Testing
- Experimental, Comparator
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorders
The Swedish Versions of ADOS and ADI-R: Psychometric Validation
Autism spectrum disorders (ASD) are early onset chronic conditions coined by deficits in social reciprocity, communication and stereotypic interests and activities.
- Trial name
- NCT01854333
- Testing
- ADOS module 1-4 or ADI-R
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Autistic Disorder
A Long-term, Extended Treatment Study of Aripiprazole in Pediatric Patients With Autistic Disorder
The objective of this study is to investigate the safety and efficacy of aripiprazole orally administered over long term in subjects who complete a short-term treatment study of pediatric Autistic Disorder (031-11-002 study).
- Trial name
- NCT01617460
- Testing
- Aripiprazole
- Where
- 5 sites in Japan
- Volunteers
- 86 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Autism Spectrum Disorder
Effect of a Wide Spectrum Nutritional Supplement on Mitochondrial Function in Children With Autism Spectrum Disorder
The objective of this study is to evaluate the metabolic effects of a comprehensive wide-spectrum supplement for children with ASD to determine whether it physiologically targets mitochondrial pathways known to be abnormal in…
- Trial name
- NCT03835117
- Testing
- Wide-spectrum nutritional supplement
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Rossignol Medical Center
Autism Spectrum Disorder
Dietetic Pattern in Children With Autism Spectrum Disorders
To date, it is well documented that the gut microbiota (GM) influences numerous physiological processes in the healthy "host". The alteration of the composition and function of the intestinal microbiota, commonly referred to as…
- Trial name
- NCT04719923
- Testing
- Children with autism spectrum disorders
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Asperger's Disorder, High-functioning Autism
Adolescent Social Skills Training Program
This study is a pre-test, post-test single group design with follow-up at month three. Twenty-four individuals total will participate in this study with 6 participants in each of 4 cohorts.
- Trial name
- ASST (NCT01031823)
- Testing
- Multi-Media Social Skills Training Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autistic Disorder
Parenting Your Young Child With Autism: A Web-Based Tutorial
This study will evaluate the efficacy and user satisfaction with a web-based interactive tutorial for caregivers of young children with autism designed to a) teach parents how to promote their child's development in the core…
- Trial name
- NCT02184390
- Testing
- On LIne Parent Training Tutorial
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Center for Psychological Consultation
Autism Spectrum Disorder
Movement-Based Digital Game Intervention for Children With Autism Spectrum Disorder
The goal of this study is to learn if movement-based digital games can help improve motor skills in children aged 6-10 years with Autism Spectrum Disorder (ASD).
- Trial name
- MBDG-ASD (NCT07779525)
- Testing
- Movement-Based Digital Games
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Autistic Disorder
Clinical and Neurophysiological Evolutions Through a Functional Rehabilitation of Social Communication in ASD
This study aims to identify clinical and biological markers which would allow to evaluate precisely the evolution of children with autism spectrum disorders throughout intervention.
- Trial name
- NCT02444117
- Testing
- functional rehabilitation of social communication
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Tours
Autism Spectrum Disorder
Autologous Umbilical Cord Blood Infusion for Children With Autism Spectrum Disorder (ASD)
This study is a prospective phase 1 single-center trial designed to determine the safety of a single intravenous infusion of autologous umbilical cord blood in children with Autism Spectrum Disorder (ASD) and assess the…
- Trial name
- NCT02176317
- Testing
- Autologous Umbilical Cord Blood
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Autism Spectrum Disorder
Communication Intervention for Toddlers With Autism
The goal of this study is to conduct an efficacy trial to determine whether an early communication intervention which blends two evidence-based interventions, Enhanced Milieu Teaching (EMT) and Joint Attention, Symbolic Play and…
- Trial name
- J-EMT (NCT02595697)
- Testing
- J-EMT for Toddlers with Autism
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Autism
Parent-delivered Massage for Children With Autism
Through funding from the U.S. Maternal and Child Health Bureau, Teaching Research Institute at Western Oregon University (WOU) will be conducting research on the effect of a parent-delivered massage program on measures of autism…
- Trial name
- NCT01801696
- Testing
- Parent massage tx group, Parent massage wait-list control group
- Where
- 4 sites in United States
- Volunteers
- 103 people
- Sponsor
- Western Oregon University