Clinical trials: Autism Disorder
Autism Spectrum Disorder
Measuring Brain Inflammation in Autism
Autism spectrum disorders (ASD) are highly disabling, persistent neurodevelopmental disorders. There are no available treatments for core symptoms of ASD or biologically-based clinical biomarkers.
- Trial name
- NCT03117530
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Developmental Coordination Disorder, Autism Spectrum Disorder
An Explorative RVA of the Motor Development of Children With DCD <2y
This study compares motor development in three groups of infants (controls, DCD, DCD+ASD) before the age of 2 years using retrospective video analysis of infants in home video contexts.
- Trial name
- RVA_DCD (NCT04126395)
- Testing
- Movement Assessment Battery for Children 2(M-ABC-2), Developmental Coordination Disorder - Questionnaire (DCD-Q), Social Responsiveness Scale 2 (SRS-2)
- Where
- 2 sites in Belgium, Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Ghent
Autism, Pervasive Developmental Disorder
Evaluation and Treatment of Copper/Zinc Imbalance in Children With Autism
There are two phases to the study. The first will examine serum copper and zinc levels and copper/zinc ratio in children (ages 3-8) who have autism and compare them to levels from same sex and age children who are developing…
- Trial name
- NCT00325572
- Testing
- oral zinc and vitamin C supplements
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autism Spectrum Disorder, Autism
Immersive Room for Visual Attention in Children With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by language delay, impaired social interactions, and repetitive behaviors.
- Trial name
- NCT05930873
- Testing
- Immersive room, stimuli in a paper format
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder, Neurodevelopmental Disorders
Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders
This study entails a "proof of concept" evaluation of a novel intervention, Parents and Infants Engaged (PIE), for prodromal infants at-risk for neurodevelopmental disorders (NDs).
- Trial name
- PIE (NCT03388294)
- Testing
- Parents and Infants Engaged
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder, Parents
Virtual Reality Experiences as Tools to Support Mental Health in Parents of Children With Autism
Mindfulness is a technique that involves the intentional and non-judgmental regulation of attention to the present moment, with curiosity, openness, and acceptance, as per its definition.
- Trial name
- Mind-VR (NCT05852795)
- Testing
- Virtual Reality-mediated Mindfulness-Based Interventions, Virtual Reality-mediated Mindfulness-Based Interventions without audio guided experience
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder, Motor Disorders
Evaluation of Motor Skills, Balance, Dual Task, and Social Adaptation in Individuals with Autism
The aim of our study is to evaluate motor skills balance, dual task and social adaptation skills in individuals with autism. Our study will be conducted in Bartın Lider Special Education and Rehabilitation Center after ethics…
- Conditions
- Autism Spectrum Disorder, Motor Disorders, Social Skills
- Trial name
- NCT06777186
- Testing
- 10 meter walk test, Functional Balance, Social Adaptation Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Autism or Autistic Traits, Healthy
Development of Prosocial Behaviors and Related Brain Network in Infants of High and Low Risk of ASD
The goal of this observational study is to compare the developmental trajectories of prosocial behaviors and functional network connections in infants and toddlers at high and low risk of autism spectrum disorder (ASD).
- Trial name
- NCT06329245
- Testing
- Do not take any interventions
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorders, Autism
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment.
- Conditions
- Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified
- Trial name
- TAASD (NCT02028247)
- Testing
- Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Children With Autism Spectrum Disorder, Typical Developed Children
Investigating Handwriting Characteristics and Underlying Factor in Children With Autism Spectrum Disorder
The mechanism of the motor problem in children with autism spectrum disorder (ASD) in handwriting has been investigated in the following three aspects, including collecting dynamic handwriting performance, exploring the related…
- Trial name
- NCT06228885
- Testing
- handwriting experiment and motor ability test
- Where
- Taiwan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Autism Spectrum Disorder, Gastrointestinal Symptoms
Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder
This protocol is a blinded randomized controlled study of the effects of BB-12 with LGG at different doses in 70 healthy children with autism spectrum disorders at lower and higher doses over an 56-day period and a 28- day…
- Trial name
- NCT03514784
- Testing
- BB-12 with LGG (Higher Dose), BB-12 with LGG (Lower Dose)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Autism Spectrum Disorder
Tool for Evaluating the Effectiveness of the DENVER Protocol
Early remediation of the communicative and social difficulties of children with autism spectrum disorders (ASD) is central. However, from the age of 6-8 months, children with ASD show a lack of attention to social stimuli such as…
- Trial name
- FACECOM (NCT06253793)
- Where
- 3 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Autistic Spectrum Disorder
Nutritional Status and ASD Severity of Autistic Spectrum Disorder Children in Addis Ababa, Ethiopia; Case Control Study
The study conducts a case control analysis of the nutritional status and intake of autistic spectrum disorder diagnosed children as compared to typically developing children in Addis Ababa, Ethiopia.
- Trial name
- ASD (NCT05515913)
- Testing
- Nutritional status, Eating behavior, Urine iodine concentration
- Where
- Ethiopia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Addis Ababa University
Autism Spectrum Disorder, Autism
Examining the Effects of a Job Entry Intervention
The current study will examine the efficacy of a virtual reality (VR) intervention as well as a newly developed Kessler Foundation STRength IDentification and Expression tool (VR-STRIDE) with adolescents diagnosed with autism…
- Conditions
- Autism Spectrum Disorder, Autism, ASD
- Trial name
- IMPRESSIVE (NCT04771338)
- Testing
- VR-JIT/KF-STRIDE
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Accommodation, Daily Activities
Project Independence
This project aims to develop and test the feasibility, acceptability, and preliminary impact of a brief, online single-session intervention (SSI) for caregivers of autistic youth ages 10 to 14.
- Conditions
- Accommodation, Daily Activities, Independence, Autism
- Trial name
- NCT07572110
- Testing
- Project Independence
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Miami
Autism Spectrum Disorder
Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Researchers think brain development may be controlled by gamma-aminobutyric acid (GABA).
- Trial name
- NCT04798274
- Testing
- Continuous Theta Burst Stimulation
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder
Study to Assess the Janssen Autism Knowledge Engine in Participants With Autism Spectrum Disorder and in a Normally Developing Cohort
The purpose of this study is to evaluate the utility of and to clinically validate the Autism Behavior Inventory (ABI) in measuring clinical symptoms of Autism Spectrum Disorder (ASD) compared with other gold standard measures.
- Trial name
- NCT02668991
- Where
- 9 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Autism Spectrum Disorder
Autism & Anesthetic Exposure Study
As anesthesia is often needed for childhood surgery and procedures, researchers have examined the potential effects of anesthesia on neurodevelopment.
- Trial name
- NCT03514498
- Testing
- Dental surgery
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Physical Activity, Motor Skills Development
Feasibility and Acceptability of a Co-produced Intervention to Improve Physical Activity and Motor Competence Amongst Children With Intellectual Disabilities and/or Autism Spectrum Disorder: Movement Matters
The goal of this observational study is to find out whether an intervention designed to improve physical activity levels and movement skills is practical and acceptable for children aged 7-11 years with intellectual disabilities…
- Trial name
- MM (NCT07456514)
- Testing
- Movement Matters
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Autism Spectrum Disorder
Early Connections, Early Detection and Intervention in Infants at Risk for Autism
Early connections has two broad goals: to identify risk indices for autism spectrum disorder (ASD) in 6 to 24 month old infants who have an older sibling with ASD or infants who have an older neurotypical sibling.
- Trial name
- NCT00947700
- Testing
- Assessment, Monitoring & Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington