Clinical trials: Autism Disorder
Autism Spectrum Disorder, Autism
Efficacy of Reading Intervention on the Brain Connectivity in Autism
The overarching goal of this proposal is to test the impact of a comprehensive reading intervention program (Visualizing and Verbalizing) on changing the neurobiological mechanisms underlying reading comprehension deficits in…
- Conditions
- Autism Spectrum Disorder, Autism, Reading Problem
- Trial name
- BrainREAD (NCT05568056)
- Testing
- Visualizing and Verbalizing for Language comprehension and Thinking
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Schizophrenia
Social Cognitive Assessment in Autism and Schizophrenia
In people with schizophrenia or people with autism, impairments of social cognition are a core feature of the disease and, according to researchers who represent valuable references on this subject for the international…
- Trial name
- (ClaCoS) (NCT02660775)
- Testing
- schizophrenia, Autism, Healthy controls
- Where
- France
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Autism Spectrum Disorder (ASD
Exploring the Physiological Mechanisms of Austism Through Organoids
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder affecting approximately 1% of the population, characterized by difficulties with social interaction and communication.
- Trial name
- EXPECT HYPE (NCT07494331)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Child Safety
ESCAPE Kits for Elopement Prevention in Children With Autism
This study will evaluate elopement prevention kits for children with autism spectrum disorder who exhibit elopement behavior such as dashing or wandering away from safe settings.
- Conditions
- Autism Spectrum Disorder, Child Safety, Caregiver Stress
- Trial name
- NCT07225907
- Testing
- Elopement Prevention Kits
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Autism Spectrum Disorder
Participant(s) With Autism and High Pain Tolerance Treated With High Dose Naltrexone
High dose naltrexone with response gauged by pain tolerance as measured by the cold pressor test may help treat autism.
- Trial name
- NCT05100563
- Testing
- 50 mg naltrexone
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Sexual Health, Education, Health
Health Education and Relationships Through Theater: An RCT of Promoting Awareness Through Live Movement and Sound for Youth With Autism Spectrum Disorder (PALMS-ASD)
Teens with ASD ages 14-19 will be screened for eligibility, complete a baseline interviewer/ACASI-administered survey, and randomly assigned to either intervention or control group. The enrollment goal is 500 teens.
- Trial name
- HEART (NCT04005547)
- Testing
- Promoting Awareness through Live Movement and Sound for youth with Autism Spectrum Disorder
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Public Health Management Corporation
Autism, Dual Task
Single-Dual Task Performance in Children With Autism Spectrum Disorder and Typically Developing Children
This study aims to compare the effects of single-task and dual-task conditions on motor performance and postural control in children with Autism Spectrum Disorder (ASD) and typically developing children.
- Trial name
- NCT07323550
- Testing
- Single- and Dual-Task Condition Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Atlas University
Mental Retardation, Developmental Disabilities
Healthy Lifestyles for People With Intellectual Disabilities
Relatively few health promotion and disease prevention programs have included or targeted people with disabilities, and even fewer have focused on individuals with intellectual disabilities.
- Conditions
- Mental Retardation, Developmental Disabilities, Intellectual Disabilities
- Trial name
- HLID (NCT00597948)
- Testing
- Healthy Lifestyles Curriculum
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder
Social Motivation Intervention for Children With Autism Spectrum Disorder: Improving Peer Initiation
The purpose of this study is to investigate whether a social initiation motivation intervention (SIMI) focused on training children with ASD to initiate to peers during structured play activities will result in more frequent…
- Trial name
- NCT02360449
- Testing
- Social Initiation Motivation Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorder With Intellectual Deficiency
Recording Stress Biomarkers in Autism Spectrum Disorders
The goal of this observational study is to learn how stress affects children and young people with autism spectrum disorder (ASD).
- Trial name
- STRESSDEFIS (NCT07535801)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite Cote d'Azur
Autism Spectrum Disorder
A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
This is a non-drug study seeking to characterize different scales to measure repetitive and restrictive behaviors in different ASD sub-populations over time. This study will also explore the use of digital biomarkers.
- Trial name
- NCT03611075
- Testing
- No Intervention
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autism
Interactive Massage Intervention in Toddlers With Autism Spectrum Disorder
This randomized controlled trial aims to evaluate the efficacy of a 3-month maternal interactive massage intervention in toddlers aged 18-24 months with autism spectrum disorder (ASD).
- Trial name
- IMI-ASD (NCT07876245)
- Testing
- Maternal Interactive Massage, Behavioral
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder, Developmental Delay
A Salivary miRNA Diagnostic Test for Autism
The goal of this study is to validate a panel of miRNAs that distinguish children with autism spectrum disorder (ASD) from their non-ASD peers with a positive MCHAT-R.
- Trial name
- NCT02832557
- Testing
- Salivary collection, Vineland Adaptive Behavior Scale-III Assessment, Medical history questionaire
- Where
- United States
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Cerebral Palsy, Autism or Other Neuromotor Behavior Abnormalities Correlation With Anthropometry
Is There Any Correlation Among Neonates Anthropometry and Neuromotor Behaviour
To explore the association among anthropometric parameters and neuromotor behaviour in neonates for early identification and prediction of later neuromotor deficit.
- Trial name
- NCT05361213
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Autism Spectrum Disorder
REward SYSTem in Autism Spectrum Disorder and Addictive Disorder
An MRI Study in Subjects with Autism Spectrum Disorder and Subjects with Food Addictive Disorder compared to healthy volunteers.
- Trial name
- RESYSTAA (NCT05391113)
- Testing
- MRI, EEG
- Where
- 3 sites in France
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autism
the Efficacy of Oral Motor Therapy in Children With Autism
Children with Autism spectrum disorders have speech disorders, which in turn aggravate communication difficulties and lead to an increase in their core symptoms.
- Trial name
- NCT05406076
- Testing
- oral motor therapy, ABA
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Autism Spectrum Disorder
AI-Based Reflective Parenting Simulation for Parents of Autistic Children
This randomized controlled trial evaluates an AI-based parental simulation designed to support reflective parenting, emotional regulation, and parent-child communication among parents of autistic children aged 3 to 12 years.
- Trial name
- NCT07687381
- Testing
- AI-Based Reflective Parenting Simulation
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Autism Spectrum Disorder, Healthy
Investigating the Clinical Utility of the Oxford Virtual Autism Assessment Tool (OVAAT)
The goal of the study is to evaluate a new Autism Spectrum Disorder (ASD) diagnostic tool (Oxford Virtual Autism Assessment Tool (OVAAT)) to see whether it can: Be able to identify autistic traits Be able to distinguish between…
- Conditions
- Autism Spectrum Disorder, Healthy, Neurotypical
- Trial name
- NCT06582290
- Testing
- Oxford Virtual Autism Assessment Tool (OVAAT)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oxford Health NHS Foundation Trust
Cortical Excitability, Brain Stimulation
Cortical Excitability and Role of Non Invasive Brain Stimulation in ADHD and AUTISM
This double-blind, randomized, sham-controlled clinical trial will evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on children and adolescents with attention-deficit/hyperactivity disorder (ADHD) or…
- Conditions
- Cortical Excitability, Brain Stimulation, ADHD, Autism
- Trial name
- NCT07315217
- Testing
- Active repetitive transcranial magnetic stimulation (rTMS)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Neurodevelopmental Disorders
The Effect of Physical Activity Autonomic Response of Autism Spectrum
This study will investigate the effect of physical activity on autism spectrum disorder (ASD) in individuals with ASD of different age groups through measuring the hemodynamic, heart activity and respiratory system parameters.
- Trial name
- NCT05725733
- Testing
- Physical Therapy
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Jazan