Clinical trials: Autism Spectrum Disorder (ASD)
Autism Spectrum Disorder
Modulation of the Activity of the Cerebellum in Autism (MACA)
Research on the involvement of the cerebellum in social understanding behavior and the mentalizing brain system has just begun. Knowledge about the neurobiology of social understanding is important for understanding the ways to…
- Trial name
- MACA (NCT05781412)
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beatriz Catoira
Stem Cell Transplantation
Autologous Bone Marrow Stem Cell Therapy Combined With Psychological Therapy and Rehabilitation for Autism
The aim of this study was to evaluate the safety and effectiveness of autologous bone marrow mononuclear stem cells combined with Psychological Therapy and Rehabilitation for Autism children
- Trial name
- ASPRA (NCT03225651)
- Testing
- Stem cell transplantation, Psychological therapy and Rehabilitation
- Where
- Vietnam
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Sensory Integration Dysfunction
The Relationship Between Brain Volume and Sensory Integration in Autistic and Attention Deficit Hyperactivity Disorder.
The relationship between brain volume and sensory integration in children and adolescence with attention deficit hyperactivity disorder and autistic spectrum disorder; comparative study
- Trial name
- NCT05260502
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Assiut University
Autistic Disorder
Associative Memory in Autism Spectrum Disorder
The aim of this study is to investigate the neural substrates of associative memory in Autism Spectrum Disorder using both behavioural and EEG assessments.
- Trial name
- MEM-TA (NCT02265094)
- Testing
- Electroencephalography, Neuropsychological assessment
- Where
- France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Autism, Pain
Pain in Adults With Autism Spectrum Disorder
Pain insensibility is often described in people with autism. The aim of this study is to test the pain perception in adults with autistic spectrum disorder without intellectual disability.
- Trial name
- DOUPA (NCT02277756)
- Testing
- thermode
- Where
- France
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Autism Spectrum Disorder
Age-related Changes in Myeloarchitectonics Across Adulthood in Autism Spectrum Disorder
There is increasing awareness in the Autism Spectrum Disorder (ASD) research field about the deficit of knowledge with regard to the neurobiological, cognitive, and behavioral changes that occur in adults with ASD across the…
- Trial name
- NCT04108312
- Testing
- Anatomical MRI Scan
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Autism, Autism Spectrum Disorder
Milieu Teaching-AV: Adaptation of Milieu Teaching That Encourages Looking to the Mouth
This project will look at Milieu Teaching (i.e., a language intervention) that encourages looking to audiovisual speech cues (Milieu Teaching-AV) for infants with autistic older siblings (Baby Sibs), who are highly likely be…
- Conditions
- Autism, Autism Spectrum Disorder, Autism, Susceptibility to, 6
- Trial name
- MilieuTeach-AV (NCT07494513)
- Testing
- Milieu Teaching-AV, Milieu Teaching-NoAV
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Autism Spectrum Disorder, Autism
Efficacy of Reading Intervention on the Brain Connectivity in Autism
The overarching goal of this proposal is to test the impact of a comprehensive reading intervention program (Visualizing and Verbalizing) on changing the neurobiological mechanisms underlying reading comprehension deficits in…
- Conditions
- Autism Spectrum Disorder, Autism, Reading Problem
- Trial name
- BrainREAD (NCT05568056)
- Testing
- Visualizing and Verbalizing for Language comprehension and Thinking
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Autism Spectrum Disorder
Feasibility of Using Telepractice to Provide Modified Interaction Guidance.
The purpose of this study is to determine the feasibility of using telepractice to provide Modified Interaction Guidance (MIG) to caregivers and their child with autism.
- Trial name
- NCT03972254
- Testing
- Modified Interaction Guidance
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Autism Spectrum Disorder, Obesity, Childhood
A YouTube Curriculum for Children With Autism and Obesity
Parents as primary caregivers play an important role in shaping children's mealtime and eating behaviors; and in preventing weight gain.
- Trial name
- NCT06259539
- Testing
- YouTube nutrition education
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Autism Spectrum Disorder
Activities of Daily Living Participation Characteristics Among School-Aged Children With Autism Spectrum Disorder
This study aimed to investigate the performance of activities of daily living (ADL) among 53 children ages 6-10 years: 17 with high-severity ASD (HS-ASD), 16 with low-severity ASD (LS-ASD), and 20 controls with typical…
- Trial name
- NCT05186103
- Testing
- observation
- Where
- Israel
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Sara Rosenblum
Baker Gordon Syndrome, Rare Neurodevelopmental Conditions
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN)
Rare genetic neurodevelopmental disorders, such as Syt-1 or Baker Gordon Syndrome (BAGOS) arise from mutations in genes essential for brain development and function, often disrupting neurotransmission and neuronal connectivity.
- Conditions
- Baker Gordon Syndrome, Rare Neurodevelopmental Conditions, Rare Neurogenetic Conditions, Syt-1 Disorder
- Trial name
- NCT07329257
- Testing
- No Intervention: Observational Cohort
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Sexual Health, Education, Health
Health Education and Relationships Through Theater: An RCT of Promoting Awareness Through Live Movement and Sound for Youth With Autism Spectrum Disorder (PALMS-ASD)
Teens with ASD ages 14-19 will be screened for eligibility, complete a baseline interviewer/ACASI-administered survey, and randomly assigned to either intervention or control group. The enrollment goal is 500 teens.
- Trial name
- HEART (NCT04005547)
- Testing
- Promoting Awareness through Live Movement and Sound for youth with Autism Spectrum Disorder
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Public Health Management Corporation
Autism Spectrum Disorder
Feasibility Controlled Trial of an 8-session Group Intervention for Siblings of Children Who Have ASD
A feasibility controlled trial of an eight-session group intervention for siblings of children who have an Autism Spectrum Disorder (ASD). Children will be recruited from a multi-academy trust of nine schools.
- Trial name
- NCT04714606
- Testing
- Sibling support group, None - control condition
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Cortical Excitability, Brain Stimulation
Cortical Excitability and Role of Non Invasive Brain Stimulation in ADHD and AUTISM
This double-blind, randomized, sham-controlled clinical trial will evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on children and adolescents with attention-deficit/hyperactivity disorder (ADHD) or…
- Conditions
- Cortical Excitability, Brain Stimulation, ADHD, Autism
- Trial name
- NCT07315217
- Testing
- Active repetitive transcranial magnetic stimulation (rTMS)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Autism Spectrum Disorder
Smartphone-Based Neurobehavioral Assessments as a Diagnostic Aid in Autism
Retrospective case-control study to assess the diagnostic accuracy in autism spectrum disorder (ASD) of a new smartphone-based platform designed to conduct neurometric evaluations by measuring facial and behavioural reflexes.
- Trial name
- NCT06497218
- Testing
- Blinklab diagnostic device
- Where
- Morocco
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Blinklab Limited
Autism, Autism Spectrum Disorder
A Behavioral Intervention for Ameliorating Sleep Problems in Children With ASD
The present study will test the effectiveness of a behavioral intervention program that targets sleep problems in 1.5-5-year-old children with ASD.
- Conditions
- Autism, Autism Spectrum Disorder, Sleep
- Trial name
- NCT04539990
- Testing
- Behavioral treatment for sleep difficulties
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Autism Spectrum Disorders, Mood Disorders
Multidimensional Measurement of Psychopharmacological Treatment Response
The study examines actigraphic, observational, psychometric and associated repeated measurements obtained prior to and during psychopharmacological treatment.
- Conditions
- Autism Spectrum Disorders, Mood Disorders, Sleep Disorders, Attention Deficit Disorders
- Trial name
- NCT01184235
- Testing
- Pharmacological Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Child Psychopharmacology Institute
Autism Spectrum Disorder, Complication of Prematurity
Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Preterm children are at increased risk for autism spectrum disorders, with an estimated rate of 10%. In the US, about 1 in 8 pregnancies ends with a premature birth.
- Trial name
- ASD-CXCR4 (NCT01686685)
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization