Clinical trials: Autism Spectrum Disorder (ASD)
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism
Functional MRI of Cognitive Control in Autism
This study aims to investigate the role of fronto-striatal circuits and cognitive control in the perseverative and inflexible behavior that is a defining feature of autism.
- Trial name
- NCT00463164
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Autism Spectrum Disorder
Autism, Emotional Processing, and the Amygdala
Empathy imbalance hypothesis suggests that individuals with autism Spectrum Disorder (ASD) should have a deficit of cognitive empathy and a surfeit of emotional empathy.
- Trial name
- NCT04549506
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yawei Cheng
Autism Spectrum Disorder, Ophthalmic Abnormalities
The Gluten-Casein-free Diet in Children With Autism: A Clinical Results of the Ophthalmic and Behavioral Manifestations
To evaluate the efficacy of eight weeks of GFCF in children with ASD on autistic symptoms and ophthalmic findings such as corneal reflex, interpupillary distance (IPD) and pupil size.
- Trial name
- NCT05848336
- Testing
- Gluten Free Casein Free Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Autism Spectrum Disorder
Training Early Social Language in Autism
The aim of the study is to determine whether a targeted behavioral intervention can lead to both changes in early communication skills and in neural responses in toddlers and preschoolers with autism.
- Trial name
- TESLA (NCT03427138)
- Testing
- Jasper, Parent Education
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Autism Spectrum Disorder
Autism Spectrum Disorder: BAEPs Findings and Behavioral Responses to Sounds
There are many studies in the literature that study the sensory profile of children with autism spectrum disorder (ASD), which can essentially have three types of behavior: (1) Registration, (2) Seeking, (3) Sensitivity, and (4)…
- Trial name
- NCT05520632
- Testing
- Brainstem Auditory Evoked Potentials
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciências Biomédicas Abel Salazar
Autism Spectrum Disorders, Autism
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment.
- Conditions
- Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified
- Trial name
- TAASD (NCT02028247)
- Testing
- Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism, Autism Spectrum Disorder
Optimizing Outcomes for Young Autistic Children
The overarching goal of the proposed study is to: (a) determine how best to sequence two parent-mediated interventions: a social communication intervention (Project ImPACT, Improving Parents as Communication Teachers) and a…
- Trial name
- NCT05926687
- Testing
- Social Communication, Disruptive Behavior, Social Communication + Reduce Frequency
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autism Spectrum Disorder, Adverse Childhood Experiences
Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition
Using a metabolomics approach in combination with eye-tracking data, this research study proposes to gather evidence from two interrelated body systems (gut and brain) in order to assess how the microbiome is involved in stress…
- Conditions
- Autism Spectrum Disorder, Adverse Childhood Experiences, Stress Reaction
- Trial name
- NCT06269614
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Autism Spectrum Disorder
STEPS Implementation Trial
This study will inform understanding of how to support emerging adults with autism spectrum disorder (ASD). The investigators will use a theoretically informed and research-based transition support program developed for people…
- Trial name
- NCT05695885
- Testing
- STEPS, Services as usual (SAU)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
ASD
A Pilot Study to Develop a Behavior-based Screening Protocol for Early Diagnosis of Autism Spectrum Disorders
This study aims to collect basic data to develop a tool for early screening of autism spectrum disorder (ASD) in children and adolescents through eye tracking and motion analysis.
- Trial name
- NCT06339359
- Testing
- Exmainations including clinical measurement, kinetic and kinematic measurmetns. Behavioral assessments
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Autism Spectrum Disorders
The Multi-Media Social Skills Project for Adults
This study is investigating the development of a social skills training program for adults with Asperger's Syndrome or high-functioning autism, ages 18 to 35 years. The Principal Investigator for this study is Dr.
- Trial name
- NCT02995564
- Testing
- social skills therapy
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autism Spectrum Disorder
The Predictors for Activity and Participation in Children With ASD: A Follow-up Study
Developmental function and Participation in life and school activities in patients with autism spectrum disorder: A follow-up study
- Trial name
- NCT03700190
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Autism, Autistic Disorder
Relationship Training for Children With Autism and Their Peers
This study will determine whether peer interaction training interventions are effective in enhancing the social relationships of children with autism.
- Trial name
- NCT00095420
- Testing
- Social skills training targeting children with autism, Social skills training of peers without autism, Combination treatment of social skills/education about autism
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Tuberous Sclerosis, Autism Disorder
Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)
The purpose of this study is to characterize the developmental phenotype of ASD and ID and to identify biomarkers using advanced MRI methodology and electrophysiological biomarkers of synaptic function and connectivity predictive…
- Conditions
- Tuberous Sclerosis, Autism Disorder, Intellectual Disability
- Trial name
- NCT02461459
- Where
- 6 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Autism
A Clinical Trial to Study the Safety and Efficacy of Bone Marrow Derived Autologous Cells for the Treatment of Autism
This clinical trial is a single Arm, single centre to check the safety and efficacy of bone marrow derived autologous mono nuclear cells (MNC) (100 million per dose). Trial to be conducted for 36 months.
- Trial name
- BMCA (NCT01836562)
- Testing
- STEM CELL THERAPY
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chaitanya Hospital, Pune
Developmental Disability, Autism Spectrum Disorder
Association Between Motor Skills and Sensory Profiles in Children With Typical and Atypical Development Aged 4 to 11 Years
Background and Justification Childhood developmental disorders, such as Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), and Developmental Coordination Disorder (DCD), pose significant challenges…
- Conditions
- Developmental Disability, Autism Spectrum Disorder, Development Coordination Disorder, Attention Deficit Disorder With Hyperactivity
- Trial name
- MOTISEN (NCT06764810)
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Autism, Asperger's Syndrome
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT01178385
- Testing
- Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism, Autism Disorder
How Virtual Reality Can Help Neurodivergent Children Improve Their Attention
The goal of this study is to determine whether playing a virtual reality (VR) game can help neurodivergent children pay attention for extended periods.
- Conditions
- Autism, Autism Disorder, ADHD - Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder
- Trial name
- Attend-VR (NCT07341204)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Autism Spectrum Disorder, Intellectual Disability, Mild
Computer-Mediated Intervention to Enhance Emotional Competence in Children With Autism in Schools
Autism spectrum condition (ASC) is a neurodevelopmental disorder characterized fundamentally by social deficits. Emotional competence - the ability to express, recognize, understand, and regulate emotions - is a key aspect of…
- Trial name
- NCT05902832
- Testing
- EmotiPlay
- Where
- Israel
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel