Clinical trials: Autism Spectrum Disorder (ASD)
Autistic Disorder
Oxytocin in Spectrum Autism Disorders
Observe effects of oxytocin on individuals with autism spectrum disorder
- Trial name
- OxytocinASD (NCT03183674)
- Testing
- Oxytocin
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Autism Spectrum Disorder, Mental Health Issue
Access to Tailored Autism Integrated Care Pilot Study
Children with autism spectrum disorder (ASD) represent a rapidly growing, high-priority clinical population highlighted by the NIMH and Interagency Autism Coordinating Committee due, in part, because they have multiple service…
- Trial name
- ATTAIN (NCT04293627)
- Testing
- ATTAIN
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder
Better Understand Motor Deficits Associated With Autism Spectrum Disorders: Development of an Assessment Protocol
This research is a case-control study aiming to characterize motor peculiarities (objective quantitative and qualitative measures) and its psycho-physiological correlates of children with ASD.
- Trial name
- MOTRICITE TSA (NCT05236803)
- Testing
- Testing of general motor skills, fine motor skills and occulomotricity, Questionnaires
- Where
- 4 sites in France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Autism Spectrum Disorder, Emotional Regulation
Effectiveness of Robot-Assisted Intervention and Sensory Integration Therapy in Enhancing Social-Emotional Skills in Children With Autism
This study is designed to evaluate and compare the impact of robot-assisted intervention using a smart robot (Kebbi Air) and traditional sensory integration therapy on improving social-emotional skills in children diagnosed with…
- Conditions
- Autism Spectrum Disorder, Emotional Regulation, Sensory Integration Dysfunction
- Trial name
- NCT06757673
- Testing
- Robot-Assisted Therapy using Kebbi Air, Sensory Integration Therapy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Accommodation, Daily Activities
Project Independence
This project aims to develop and test the feasibility, acceptability, and preliminary impact of a brief, online single-session intervention (SSI) for caregivers of autistic youth ages 10 to 14.
- Conditions
- Accommodation, Daily Activities, Independence, Autism
- Trial name
- NCT07572110
- Testing
- Project Independence
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Miami
Autism Spectrum Disorder
Tailoring Treatment Targets for Early Autism Intervention in Africa
Naturalistic Developmental Behavioral Interventions (NDBIs), an evidence-based early autism spectrum disorder (ASD) intervention approach, target key behaviors that help language development.
- Trial name
- NCT04068688
- Testing
- Early Start Denver Model (ESDM), Telehealth coaching
- Where
- South Africa
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Duke University
Autistic Spectrum Disorders
A Pilot Trial of a Developmental, Individual-Difference, Relationship-Bases (DIR)/Floortime for Children With Autistic Spectrum Disorders
Thirty two children age 2-6 years are recruited into the study and the randomization will be stratified for chronological age and symptom severity into 2 main groups, intervention and control.
- Trial name
- DIR (NCT00954083)
- Testing
- DIR/Floortime, Routine care
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Autism Spectrum Disorder (ASD
Monitoring Daily Mobility in Children With Autism
Children with autism spectrum disorder (ASD) often show motor abnormalities and sleep disturbances that affect behavior, learning, and family quality of life.
- Trial name
- SIMBA (NCT07519369)
- Testing
- placement of a wearable wrist sensor
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Autism Spectrum Disorder (ASD)
Coaching and Leadership in Autism Support Settings
Schools serve a large number of autistic children, yet face two critical gaps that stifle the delivery of evidence-based practices: 1) an intervention gap characterized by limited availability of evidence-based practices…
- Trial name
- CLASS (NCT07276750)
- Testing
- RUBIES, HELM, Educator Psychoeducation
- Where
- United States
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder, Anxiety
The Effects of Exercise in Anxiety in Children With ASD
This study will examine the effects of a school based exercise programme on anxiety and behaviour levels in children with autism.
- Conditions
- Autism Spectrum Disorder, Anxiety, Behavior
- Trial name
- NCT03860389
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South East Technological University
Williams Syndrome, Autism Disorder
Research on the Molecular Mechanism of Cognitive Differences Between Williams Syndrome and Autism Spectrum Disorder
Williams Syndrome (WS) is a rare neurodevelopmental disorder, usually caused by microdeletions of approximately 26 genes in the long arm (7q11.23) region of chromosome 7.
- Trial name
- WS and ASD (NCT07509879)
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Autism
MRI Study of Cerebral Blood Flow in Development Disorders in Children
The purpose of this study is reproduce the individual detection results by PET with Arterial Spin Labeling (ASL) MRI, to establish a biomarker useful in autism diagnosis.
- Trial name
- IRM-Aut (NCT02165410)
- Testing
- ASL-MRI, Diffusion tensor imaging (diffusion MRI), Resting state MRI
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Autistic Disorder
Risk Factors and Prognosis of Autism Spectrum Disorder
This case-control study with prospective follow-up aims to identify risk factors associated with autism spectrum disorder and to evaluate the prognosis of children with ASD attending Assiut University Children's Hospital.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Child Development Disorders, Pervasive
- Trial name
- NCT07818460
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Neuroinflammation, Autism Spectrum Disorder
Imaging - Clinical Evaluation of Altered Nervous System Drainage
The current study aims to evaluate the aspects of perfusion, fluid diffusivity in the interstitium and the T1 and T2 signal of the PVS and WMH.
- Trial name
- I-CLEANED (NCT06432023)
- Testing
- Magnetic resonance imaging
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder, Autism
Feasibility of Mobile Game System for Potential Treatment of Developmental Delays
The investigators will test the feasibility and preliminary efficacy of a Mobile game system meant to generate valuable data for measuring progress and building novel artificial intelligence models while delivering impactful…
- Trial name
- NCT04909710
- Testing
- Mobile Game System for Potential Treatment of Developmental Delays
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Autism
Sensory Adapted Dental Environment to Enhance Oral Care for Children With ASD
The goal of this project is to collect information that will support a later clinical trial on the effectiveness of a specially adapted dental environment for children who have difficulty tolerating oral care in the dental…
- Trial name
- SADE (NCT02077985)
- Testing
- Sensory Adapted Dental Environment
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Autism Spectrum Disorder
Psilocybin in Adults With and Without Autism Spectrum Disorder
This study will test the hypothesis that brain systems are differentially regulated by serotonin in individuals with and without Autism Spectrum Disorder.
- Trial name
- PSILAUT (NCT05651126)
- Testing
- Psilocybin 5 mg, Psilocybin 2 mg
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- King's College London
Physical Activity, Motor Skills Development
Feasibility and Acceptability of a Co-produced Intervention to Improve Physical Activity and Motor Competence Amongst Children With Intellectual Disabilities and/or Autism Spectrum Disorder: Movement Matters
The goal of this observational study is to find out whether an intervention designed to improve physical activity levels and movement skills is practical and acceptable for children aged 7-11 years with intellectual disabilities…
- Trial name
- MM (NCT07456514)
- Testing
- Movement Matters
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Autism Spectrum Disorder
Evaluation of Behavioural Psycho & Physiological Responses in People With ASD During a Blood Test in Routine Care Practice
The project is a prospective study designed to characterize behaviour and its psycho-physiological correlates of participants with ASD (children and adults) in comparison with subjects without ASD matched in age during blood test…
- Trial name
- AUTICOPP (NCT04638452)
- Testing
- Video & movements recording, Questionnaires
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Modified Atkins Diet, Autism Spectrum Disorder
Efficacy of MAD as add-on Therapy in Comparison With Standard of Care in Children With ASD
In general ketogenic diet is a recognized as an efficient non pharmacological treatment for children with refractory epilepsy. However, in the last decade, it has been tried for many neurological disorders in children including…
- Conditions
- Modified Atkins Diet, Autism Spectrum Disorder, Standard of Care
- Trial name
- NCT06315465
- Testing
- Modified Atkin's Diet with standard of care, Standard of Care
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences