Clinical trials: Autistic Disorders Spectrum
Autism Spectrum Disorders
Single Dose Intranasal Oxytocin and Cognitive Effects in Autism
Autism spectrum disorder (ASD) is a group of severe, life-long developmental disorders. Oxytocin (OT) is a neurohormone involved in both repetitive/rigid and social behaviors.
- Trial name
- NCT02493426
- Testing
- Intranasal Oxytocin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Minnesota
Harmful Stereotypies, Feeding Difficulties
Stereotypic Behaviors and Feeding Difficulties in Adults With Developmental Disabilities
Adults with developmental disabilities (DD) and autism represent a vulnerable demographic that transitions into adulthood with diverse etiologies, exhibiting a significantly higher prevalence of various challenging behaviors.
- Trial name
- NCT06920615
- Testing
- Fading and chaining combined with differential reinforcement, Differential reinforcement of high rate, Response interruption with redirection
- Where
- Norway
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Prosocial Behavior, Emotional Regulation
Comparison Between a Live Canine or Toy Dog on Prosocial Behavior and Emotional Regulation in Autistic Children
This study investigated the human-animal interaction (HAI) and bond (HAB) between a canine trained in therapy techniques or a canine plush toy and youth with autism spectrum disorder (ASD) during animal-assisted therapy (AAT)…
- Conditions
- Prosocial Behavior, Emotional Regulation, Human Animal Bonding, Human Animal Interaction
- Trial name
- NCT06915415
- Testing
- Animal-assisted therapy, Behavioral therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Arkansas, Fayetteville
Autism, Wellbeing
Evaluating a Workbook to Promote Autistic Wellbeing
The goal of this clinical trial is to examine the feasibility and acceptability of a brief guided self-help wellbeing intervention for autistic adults accessing UK secondary mental health services.
- Trial name
- NCT07630376
- Testing
- Guided self-help workbook for autistic adults
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Canterbury Christ Church University
Autism Spectrum Disorder
Effect of a Wide Spectrum Nutritional Supplement on Mitochondrial Function in Children With Autism Spectrum Disorder
The objective of this study is to evaluate the metabolic effects of a comprehensive wide-spectrum supplement for children with ASD to determine whether it physiologically targets mitochondrial pathways known to be abnormal in…
- Trial name
- NCT03835117
- Testing
- Wide-spectrum nutritional supplement
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Rossignol Medical Center
Autism Spectrum Disorder, Autism
Mitochondrial Dysfunction in Autism Spectrum Disorder
Researchers at Arkansas Children's Hospital Research Institute are conducting a study about mitochondrial function in children. The study involves up to 5 visits to Arkansas Children's Hospital with fasting blood draws…
- Conditions
- Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
- Trial name
- Mito (NCT02000284)
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Autism Spectrum Disorder
Headsprout Reading Program in Children With Autism Spectrum Disorder and Reading Delay
Headsprout is a commercially available computer-based reading program that teaches children fundamental reading skills, including phonics, fluency, and comprehension.
- Trial name
- NCT03055533
- Testing
- Headsprout reading program
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Nebraska
Autism, ASD
The Effects of Oxytocin on Complex Social Cognition in Autism Spectrum Disorders
This study examines the effects of a single dose of intranasal oxytocin (vs. placebo) on complex social cognition in adults with autism spectrum disorders.
- Trial name
- NCT01183221
- Testing
- Syntocinon
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Alexander Kolevzon
Autism
Autism - Children's Improvisational Music Therapy Evaluation
The goal of this clinical trial is to evaluate the effectiveness of individual sessions of improvisational music therapy for autistic children aged 7 - 11.
- Trial name
- CHIME (NCT06016621)
- Testing
- Improvisational Music Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 240 people
- Sponsor
- Prof Simon Baron-Cohen
Autism Spectrum Disorder
A Multi-site Double-blind Placebo-controlled Trial of Memantine Versus Placebo in Children With Autism (MEM)
This study will attempt to study the effect of memantine, on memory, and motor praxis/expressive language skills in children with autism.
- Trial name
- NCT01372449
- Testing
- Memantine
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Evdokia Anagnostou
Autism Spectrum Disorder
A Pilot Study of Microbiome in Patients With Autism Spectrum Disorder and Their Unaffected Siblings
The primary aims are to identify important gut microbiota signatures for youth with ASD, to identify dysbiosis features for different levels of ASD features and clinical courses, to search the possibility to intervene the disease…
- Trial name
- NCT05038748
- Testing
- Psychiatric diagnosis, ASD diagnosis
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Mobile-based Games for Cognitive Training in Children With Neurodevelopmental Disorders
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with characteristic deficits in social functioning and presence of stereotypic behavior.
- Trial name
- NCT04308915
- Testing
- Game-based cognitive training
- Where
- India
- Volunteers
- 14 people
- Sponsor
- Indian Institute of Technology Kanpur
Autism Spectrum Disorder
PEERS® for Italy, a Study on Social Skills Intervention for Adolescents With Autism Spectrum Disorder (ASD).
TThe research aims to verify the Italian adaptation of a parent-mediated group training focused on social skills for adolescents with autism spectrum disorder (ASD).
- Trial name
- NCT05473104
- Testing
- Program for the Education and Enrichment of Relational Skills
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- Istituto Superiore di Sanità
Autism Spectrum Disorder, Gastrointestinal Dysfunction
ASC - Autism Study
The ASC - Autism Pilot Study is a single center randomized open dose titrating phase I clinical intervention pilot trial with the aim of investigating safety and treatment effect of an allogeneic adipose tissue derived…
- Conditions
- Autism Spectrum Disorder, Gastrointestinal Dysfunction, Leaky Gut Syndrome, Mesenchymal Stromal Cells
- Trial name
- NCT05602116
- Testing
- Adipose tissue derived mesenchymal stromal/stem cells (Cell2Cure®)
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Cell to Cure ApS
Gastrointestinal Problems, Autism Spectrum Disorders
Beneficial Bacteria Treatment for Autism
This is an open-label clinical trial to investigate a combination therapy for treating gastrointestinal problems in children with autism spectrum disorders. The combination therapy includes beneficial bacteria.
- Trial name
- BBT (NCT02504554)
- Testing
- oral Vancomycin, MoviPrep, Prilosec
- Volunteers
- 18 people
- Sponsor
- Arizona State University
Autism Spectrum Disorder, Autism
Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.
Autism spectrum disorder (ASD) is a neurodevelopmental condition with core deficits in social communication and behavior, often accompanied by gastrointestinal (GI) and metabolic dysfunction.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectral Disorder
- Trial name
- GARM-Autism (NCT07546942)
- Testing
- Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Black Tie Medical, Inc.
Autism Spectrum Disorder
Effects of Cuevas Medek Exercises Children With Autism Spectrum Disorder
Autism spectrum disorders (ASDs) describe a group of neurodevelopmental conditions in which the individuals face challenges with social engagement.
- Trial name
- NCT06198166
- Testing
- Cuevas Medek, Standard kinetic programs
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder, Chronic Insomnia
Targeting Sleep in Kids With Autism Spectrum Disorder
Children with Autism Spectrum Disorder (ASD) and insomnia, and their parent(s) will undergo 8 sessions of Cognitive Behavioral Therapy designed for Children with Chronic Insomnia and ASD (CBT-CI-A).
- Trial name
- NCT02755051
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Epilepsy, Autism Spectrum Disorder
Biomarkers for Epilepsy Development and the Effect of Physical Exercise in Children With Autism
This study aims to identify novel biomarkers for epilepsy development in children with autism and to evaluate the effects of physical exercise on these biomarkers and clinical outcomes.
- Trial name
- ASD/EP (NCT07373431)
- Testing
- Physical activity program
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Skane
Autism Spectrum Disorder (ASD), Autism
Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism
The purpose of this open label trial is to examine the acceptability, tolerability, and feasibility and preliminary effectiveness of sleep restriction therapy for sleep problems in children with autism spectrum disorder (ASD).
- Trial name
- NCT06627205
- Testing
- Sleep Restriction Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University