Clinical trials: Autistic Spectrum Disorder
Child Development Disorders, Pervasive
Pharmacogenetics of Risperidone in Children With Pervasive Developmental Disorder (PDD)
The purpose of this study is to determine if the known differences in genes influence drug metabolizing enzymes and receptors that are involved in risperidone drug action.
- Trial name
- NCT00166595
- Testing
- Risperidone
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism
Study of Peer Relationships at School
The goal of this study is to compare the effects of two separate, manualized group interventions designed to improve social outcomes for young children with autism.
- Trial name
- HRSAII (NCT01011764)
- Testing
- SKILLS vs ENGAGE
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Health Resources and Services Administration (HRSA)
Autism, Parents
A Study on the Effect of Education Training on Parents With Autism Based on Denver Model
The goal of this clinical trial is to test the effects of parent training based on Denver model on parents' disease cognition level, coping style, parenting guilt, depression, anxiety and stress, quality of life, etc .
- Trial name
- NCT06126939
- Testing
- Educational training based on the Denver model
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hunan Normal University
Autism, Autism Spectrum Disorder
hCT-MSCs for Children With Autism Spectrum Disorder (ASD)
The purpose of this Phase 1 study is to determine the safety of one, two, and three intravenous infusions of human umbilical cord tissue-derived mesenchymal stromal cells (hCT-MSC), administered every two months, in children with…
- Conditions
- Autism, Autism Spectrum Disorder, ASD
- Trial name
- hCT-MSCs (NCT03099239)
- Testing
- hCT-MSC infusion
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Joanne Kurtzberg, MD
Challenging Behavior
A Single-Arm Pilot Trial for Mitigating Relapse of Severe Problem Behavior
The goal of this study is to improve how we teach self-control and communication skills to children and adolescents with challenging behaviors.
- Trial name
- NCT06732219
- Testing
- Functional Communication Training, Extinction-Correlated Stimuli, Caregiver Fading
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Auburn University
Asperger's Disorder, Mental Retardation
Cognitive Neuroscience of Autism Spectrum Disorders
Background: Autism spectrum disorders (ASDs) are a group of developmental disorders that affect communication, social interaction, and behavior.
- Conditions
- Asperger's Disorder, Mental Retardation, Children, Adult
- Trial name
- NCT01031407
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder, Autism
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost…
- Conditions
- Autism Spectrum Disorder, Autism, Anxiety, Anxiety Disorders
- Trial name
- LUNA-A (NCT06537128)
- Testing
- LUNA-Adolescent, Treatment as Usual
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder, Autism
Early Diagnostic Response Model (EDRM)
Babies Can't Wait (BCW) in Georgia will be referring families with children seeking an autism spectrum disorder (autism) diagnosis at the Emory Autism Center's (EAC) Child Screening and Assessment Clinic.The objective of this…
- Trial name
- NCT05419895
- Testing
- Early Diagnostic Response Model (EDRM)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Emory University
PTEN Hamartoma Tumor Syndrome
Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients
The purpose of this study is to develop a survey completed by parents, caregivers, or other informants that evaluates several important domains of functioning relevant to individuals with neurodevelopmental disorders, including…
- Trial name
- NCT05671107
- Testing
- NET
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 300 people
- Sponsor
- John Carroll University
Autism, Food Allergies
Treatment of Autistic Children Using NAET Procedures
1. Purpose of this study is to determine whether NAET procedures are effective in the treatment of children with allergy-related autism spectrum disorders in restoring their verbal and nonverbal communication. 2.
- Trial name
- NCT00277407
- Testing
- NAET with acupressure and/or chiropractic procedures
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Nambudripad's Allergy Research Foundation
Autism Spectrum Disorder
Pediatric Massage for Children With Autism Spectrum Disorder
This study was designed as a randomized controlled clinical trial of pediatric massage for children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04220086
- Testing
- Pediatric massage therapy, Usual care, No intervention
- Where
- 2 sites in China
- Volunteers
- 78 people
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder
Emotional Skills Training with Social Robot
Autism is a neurodevelopmental disorder that involves difficulties especially in the sphere of social interaction, social communication, and restricted and stereotyped behavior patterns.
- Trial name
- NCT06179953
- Testing
- NAO intervention, Traditional intervention
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT04111874
- Testing
- Cognitive Behavioral Teletherapy LTA, Cognitive Behavioral Teletherapy STA
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder, Neurofibromatosis 1
From Molecules to Cognition: Inhibitory Mechanisms in ASD and NF1
This study aims to investigate synaptic physiology and behavioral inhibition in patients with NF1 and ASD and to answer whether inhibitory deficits at these levels are modulated by lovastatin.
- Trial name
- ASD/NF1inhib (NCT03826940)
- Testing
- Lovastatin 60 MG
- Where
- Portugal
- Volunteers
- 16 people
- Sponsor
- University of Coimbra
Autism Spectrum Disorder
Role of Folinic Acid in Improving the Adaptive Skills and Language Impairment in Children With Autism Spectrum Disorder
No such study has been conducted in Pakistan so the primary objective of this study was to determine the role of folinic acid in improving the speech and adaptive skills while secondary objective was improvement of stereotype…
- Trial name
- NCT05013164
- Testing
- Folinic Acid
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Autistic Youth, Nintendo Exergaming Group, No Intervention Control Group
COMPARING EFFECTS OF NINTENDO EXERGAMING TO A NO INTERVENTION CONTROL GROUP
This is a pilot randomized clinical trial to evaluate the feasibility and acceptability, and preliminary outcomes of delivering a Nintendo Switch exergaming (NE group) intervention in a group of autistic youth with autism…
- Trial name
- NCT07720427
- Testing
- Nintendo Switch Exergaming
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Delaware
Autism Spectrum Disorder (ASD
RCT of SCERTS (Social Communication, Emotional Regulation, Transactional Support) Program for Children With Autism Spectrum Disorder
This randomized control trial aims to assess the efficacy of the SCERTS intervention in children aged 3-6 years diagnosed with mild to moderate Autism Spectrum Disorder (ASD).
- Trial name
- NCT06733324
- Testing
- SCERTS (Social Communication, Emotional Regulation, Transactional Support), Behavioral Treatment, Speech Therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Aisha Saleem
Autism
Investigation of Neuroserpin as an Autism Candidate Gene
Previously it has been shown that Familial Encephalopathy with neuroserpin inclusion bodies (FENIB) patients develop abnormalities that partially overlap with Autism Spectrum disorders (ASD), confounded with additional features…
- Trial name
- NCT00917683
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autism
Treatment of Children With Autism Spectrum Disorders and Epileptiform EEG With Divalproex Sodium
The purpose of this study is to determine if treatment of epileptiform abnormalities in children with autism spectrum disorder will improve any behaviors in these children.
- Trial name
- NCT02094651
- Testing
- divalproex sodium
- Where
- 2 sites in United States
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder
Comparison of DSM-IV-TR and DSM-5 for ASD
The study aim is to prospectively compare DSM-IV-TR and DSM-5 criteria for Autism Spectrum Disorder (ASD) in a sample of 250 children and adolescents who meet DSM-IV-TR criteria for ASD and 150 children and adolescents referred…
- Trial name
- NCT02296502
- Testing
- DSM
- Where
- 5 sites in United States
- Volunteers
- 439 people
- Sponsor
- University of Pittsburgh