Clinical trials: Autoimmune Disorder
Rheumatoid Arthritis, Psoriatic Arthritis
Mindfulness Based Stress Reduction in Rheumatic Diseases
This study will assess the mental health and clinical benefits of Mindfulness Based Stress Reduction (MBSR) in patients with rheumatic disease who have anxiety or depression.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Scleroderma
- Trial name
- MBSR (NCT03411057)
- Testing
- Mindfulness Based Stress Reduction (MBSR), Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Osteoarthritis, Avascular Necrosis
A Clinical Investigation of the Comprehensive®, BioModular®, and Bi-Angular® Shoulder Systems
The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of Biomet Humeral Stems
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Humeral Fractures
- Trial name
- NCT00699270
- Sponsor
- Biomet Orthopedics, LLC
Rheumatoid Arthritis
Orofacial Evaluation in Women With Rheumatoid Arthritis
Rheumatoid arthritis (RA) can affect any synovial joint. Unlike the hand, ever so valued in the physical examination of patients with RA, the joints in the area of the jaw and neck may also be affected in this disease and have…
- Trial name
- NCT01616641
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Autoimmune Disease, Neurologic Autoimmune Disease
Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases
This phase II trial studies the side effects and how well carmustine, etoposide, cytarabine and melphalan together with antithymocyte globulin before a stem cell transplant works in treating patients with autoimmune neurologic…
- Conditions
- Autoimmune Disease, Neurologic Autoimmune Disease, Autologous Transplant Autoimmune, Multiple Sclerosis Transplant
- Trial name
- NCT00716066
- Testing
- Anti-Thymocyte Globulin, Autologous Hematopoietic Stem Cell Transplantation, Carmustine
- Where
- 3 sites in United States
- Volunteers
- 53 people
- Sponsor
- Fred Hutchinson Cancer Center
Arthritis, Juvenile Rheumatoid, Medication Adherence
Drug Compliance and Affecting Factors in Juvenile Idiopathic Arthritis
The goal of this observational study is to learn about the drug compliance of patients with juvenile idiopathic arthritis and, to figure our factors that affect the compliance.
- Conditions
- Arthritis, Juvenile Rheumatoid, Medication Adherence, Quality of Life
- Trial name
- NCT06000566
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people
- Sponsor
- Yesfa Sebnem Ozbay
Systemic Lupus Erythematosus
Aspirin Resistance in Systemic Lupus Erythematosus (SLE)
This study examine whether patients with lupus respond to aspirin , and if not, if that is related to inflammation. We examine the ability of aspirin to inhibit the production of thromboxane in patients with lupus and controls…
- Trial name
- NCT00731302
- Testing
- aspirin and meloxicam
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Myasthenia Gravis, Generalized
A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis
The purpose of this study is to evaluate the pharmacodynamic (PD) effect, safety, and tolerability of Povetacicept in participants with generalized myasthenia gravis (gMG).
- Trial name
- ETNA (NCT07501702)
- Testing
- Povetacicept
- Where
- 31 sites in United States, Australia and 3 more
- Volunteers
- 34 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Arthritis, Rheumatoid
Observational Study of Meloxicam in Any Labeled Indication
Evaluation on the amelioration of symptom intensity of the indication and to evaluate drug tolerability.
- Trial name
- NCT02182739
- Testing
- Meloxicam
- Volunteers
- 13,039 people
- Sponsor
- Boehringer Ingelheim
Healthy, Type 1 Diabetes
Subcutaneous Administration of Lisofylline to Healthy Normal Subjects and Subjects With Type 1 Diabetes
Type 1 diabetes mellitus (T1DM) is an autoimmune disease. Autoimmune diseases happen when the immune system does not identify part of the body as belonging to it.
- Trial name
- NCT00896077
- Testing
- Lisofylline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DiaKine Therapeutics, Inc.
NMO Spectrum Disorder
Monoclonal Antibody-Based Therapies for AQP4-Positive NMOSD
The primary objective of this registry study is to evaluate the therapeutic efficacy and safety profiles of distinct monoclonal antibody-based therapies for aquaporin-4 immunoglobulin G-seropositive neuromyelitis optica spectrum…
- Trial name
- NCT06885957
- Testing
- Mab Therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Type 1 Diabetes, Hypoglycemia
Insulin Management for Exercise in Patients With Type 1 Diabetes
The purpose of this study is to compare the time spent in glucose target range (4.0-10.0 mmol/L) during exercise and in recovery using three different basal insulin management strategies for prolonged aerobic exercise: A) pump…
- Conditions
- Type 1 Diabetes, Hypoglycemia, Physical Activity
- Trial name
- NCT03130101
- Testing
- Change in their basal insulin rate
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- York University
Type 1 Diabetes
Effect of Hyperglycemia on Gastric Emptying Interactions With Pramlintide
To examine the influence of acute glycaemia (normoglycaemia and hyperglycaemia) on gastric emptying kinetics in patients with type 1 diabetes and non diabetic subjects when treated with subcutaneous (SC) injections of pramlintide.
- Trial name
- NCT00489645
- Testing
- pramlintide
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Myasthenic Crisis, Upper Respiratory Infection
Incidence and Risk of Influenza in Myasthenic Patients
Upper respiratory infection , including influenza, may exacerbate the symptoms of myasthenia gravis (MG), which is an autoimmune disease that causes muscle weakness and, in some cases, can precipitate a myasthenic crisis In the…
- Trial name
- NCT03884777
- Volunteers
- 400 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Rheumatoid Arthritis
Observational Trial With Enbrel
The diagnosis, evaluation and treatment of rheumatoid arthritis (RA) continue to undergo rapid change. Randomized controlled trials such as the TEMPO study have demonstrated the efficacy and safety of the combination of…
- Trial name
- NCT00488475
- Testing
- etanercept
- Where
- Germany
- Volunteers
- 4,945 people
- Sponsor
- Pfizer
Multiple Sclerosis
An Observational Study on the Progression of Clinically Isolated Syndrome to Multiple Sclerosis Over a 2-year Period
This is a prospective, multicentric, observational study with a 2 years recruitment period. The purpose of the study is to observe the multiple sclerosis (MS) progression of subjects since their first episode of neurological…
- Trial name
- NEO (NCT01112657)
- Where
- 6 sites in Taiwan
- Volunteers
- 154 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Chronic Pain, Juvenile Idiopathic Arthritis
Turkish Validity and Reliability of Pain Catastrophizing Scale-Child (PCS-C)
Perception of chronic pain and related disability; occurs through the interaction of physiological and psychological processes. Pain catastrophizing is a cognitive attribution style characterized by a negative mindset and…
- Trial name
- NCT05436301
- Testing
- Pain Catastrophizing Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Thyroiditis, Autoimmune
The Effect of Thyroid Antibodies on Female Reproductive Function and Pregnancy Outcomes
Some women at reproductive age have positive antithyroid antibodies (ATAs). Thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb) are the most common ATAs.
- Trial name
- NCT04952012
- Testing
- LT4
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Multiple Sclerosis
Silent Progression Activity Monitoring - SPAM Study
Real-World Data (RWD) exploring the natural history of MS suggested that relapses do not significantly influence the progression of irreversible disability.
- Trial name
- SPAM (NCT05650281)
- Testing
- NO INTERVENTION
- Where
- France
- Volunteers
- 2,230 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Multiple Sclerosis
Effects of Exercises in MS on Postural Control With Dual Task
Multiple sclerosis is a progressive neurological disease that associated with demyelinization and axonal damage. Decreased postural control is one of the initial symptom of disease.
- Trial name
- MScombined (NCT03718819)
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Dokuz Eylul University
Multiple Sclerosis
Endurance and Walking Training by Nordic Walking in Multiple Sclerosis
Walking capacity is one of the most valuable body functions among persons with multiple sclerosis (MS) and it is one of the most frequently affected, even in early stages of the disease.
- Trial name
- NCT03976128
- Testing
- Nordic Walking Training, Conventional endurance training
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Multiple Sclerosis Center of Catalonia
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