Clinical trials: Autoimmune Disorder
Type 1 Diabetes Mellitus
Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus
Phase 2 Trial of BMF-219 in Participants with Type 1 Diabetes Mellitus.
- Trial name
- NCT06152042
- Testing
- BMF-219
- Where
- 11 sites in United States, Canada
- Volunteers
- 37 people
- Sponsor
- Biomea Fusion Inc.
Multiple Sclerosis, Relapsing-Remitting
Impact of the BETACONNECT Auto-injector on BETASERON Therapy Adherence and Patient Satisfaction
The primary objective of this study is to assess adherence and persistence to BETASERON therapy in patients who are using the BETACONNECT auto-injector device (BETACONNECT device).
- Trial name
- NCT02652091
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046), BETACONNECT device
- Where
- 23 sites in United States
- Volunteers
- 146 people
- Sponsor
- Bayer
Type 1 Diabetes
A Trial Investigating the Accuracy of Continuous Glucose Monitor Systems ("Supersapiens" Abbott Libre Sense and Dexcom G6) During Exercise in People With Normal Glucose Tolerance
A two-phase, observational trial in an exercise laboratory and a prospective real-world setting to test the hypothesis that The Libre Sense Glucose Sport device has acceptable accuracy in people with normal glucose tolerance and…
- Trial name
- SuperComEx (NCT06034574)
- Testing
- Continuous glucose monitoring
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Type 1 Diabetes Mellitus
Outpatient Control-to-Range: System and Monitoring Testing
A single arm, single treatment study is proposed to assess the feasibility of the AP Platform (cell phone + Control to Range system) outside of a hospital based clinical research center.
- Trial name
- NCT01578980
- Testing
- Outpatient Control-to-Range
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Rheumatoid Arthritis
Vaccination Against Pertussis, Tetanus and Diphtheria in Patients Suffering From Rheumatoid Arthritis
Pertussis is an acute respiratory infection caused by Bordetella pertussis. Rates of recent B. pertussis infection between 8%--26% have been reported among adults with cough illness of at least 5 days duration who sought medical…
- Trial name
- NCT01301703
- Testing
- Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Systemic Lupus Erythematosus
Centrally Acting ACE Inhibition in SLE
SLE is a chronic autoimmune disease that often involves multiple systems and organs of the body. An autoimmune disease is one which your immune system attacks the cells and tissues in different parts of the body.
- Trial name
- NCT04486118
- Testing
- Lisinopril Pills, Benazepril Pill
- Where
- 7 sites in United States
- Volunteers
- 36 people
- Sponsor
- Northwell Health
Type 1 Diabetes Mellitus
Protege Extension Trial - Long Term Follow Up Trial for Subjects Who Completed the Protege Study (CP-MGA031-01)
The purpose of this study is to assess the long term safety and efficacy in subjects with Type 1 Diabetes Mellitus who completed the Protege Study (CP-MGA031-01).
- Trial name
- NCT00870818
- Testing
- Blood samples for safety, Patient reported outcome questionnaires, Analysis of T-cell subsets
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- MacroGenics
Multiple Sclerosis (MS), Periodontal Diseases
Prevalence of Periodontitis in Egyptian Multiple Sclerosis Patients.
The goal of this observational study is to explore the association between multiple sclerosis and periodontal disease in a sample of Egyptian population The main question it aims to answer is: Is there an association between MS…
- Trial name
- NCT07195110
- Where
- Egypt
- Volunteers
- 293 people
- Sponsor
- Cairo University
Antiphospholipid Syndrome
The BeLimumab Antiphospholipid Syndrome Trial (BLAST)
AIM: The primary objective of the BeLimumab Antiphospholipid Syndrome Trial (BLAST) is to evaluate the safety and tolerability of belimumab for up to 24 months in patients with persistent aPL positivity and clinical features…
- Trial name
- BLAST (NCT05020782)
- Testing
- Belimumab
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Turin, Italy
Type 1 Diabetes
Team Clinic: Virtual Expansion of an Innovative Multi-Disciplinary Care Model for Adolescents and Young Adults With Type 1 Diabetes
Team Clinic is a new care approach for middle and high school aged patients living with T1D and their families. This study is a 15-month randomized control trial (RCT) that consists of Virtual Team Clinic Care appointments…
- Trial name
- NCT04190368
- Testing
- Team Clinic Care, Standard Care
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Children's Hospital Los Angeles
Juvenile Rheumatoid Arthritis
Study of Gammalinolenic Acid for Juvenile Rheumatoid Arthritis
OBJECTIVES: I. Determine the efficacy and safety of gammalinolenic acid in the treatment of childhood arthritis.
- Trial name
- NCT00004420
- Testing
- gamma-Linolenic acid
- Volunteers
- 50 people
- Sponsor
- FDA Office of Orphan Products Development
Diabetes Mellitus, Type 1, Ischemia
Non-enhanced Magnetic Resonance Angiography of Diabetic Ischemic Lower Limbs
Diabetic foot ulcers often progresses after many years of diabetes where the patients system is so damaged that normal heeling of ulcers cannot happen.
- Conditions
- Diabetes Mellitus, Type 1, Ischemia, Foot Ulcer
- Trial name
- NCT01614379
- Where
- 2 sites in Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Multiple Sclerosis, Upper Extremity Problem
Upper Extremity Motor Imagery Functional Skills and Quality of Life in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory and autoimmune disease of the central nervous system (CNS) characterised by axonal loss and demyelination. MS is characterized by myelin, oligodendrocyte and axon damage.
- Conditions
- Multiple Sclerosis, Upper Extremity Problem, Quality of Life, Image, Body
- Trial name
- MotorImagery (NCT06572059)
- Testing
- assesments for once
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Telenursing, Adolescent
Tele Nursing Application For Type 1 Diabetes Mellitus Adolescents
Studies have shown that tele-nursing practice is effective in children with Type 1 Diabetes Mellitus, but the number of studies conducted is very few.
- Conditions
- Telenursing, Adolescent, Type 1 Diabetes Mellitus
- Trial name
- NCT05211479
- Testing
- educational intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- University of Yalova
Secondary Progressive Multiple Sclerosis, Primary Progressive Multiple Sclerosis
Safety Study of an Immunomodulating Microparticle to Treat Progressive Multiple Sclerosis
The purpose of the study is to determine the safety and tolerability, dose-limiting toxicities, maximum tolerated dose, and recommended therapeutic dose of intravenously administered MIS416 weekly in patients with chronic…
- Trial name
- NCT01191996
- Testing
- MIS416
- Where
- New Zealand
- Volunteers
- 34 people
- Sponsor
- Innate Immunotherapeutics
Covid19
The Relationship Between COVID-19 and Autoimmune Diseases, Lessons From Practice
The study explore the relationship between COVID-19 and the induction of autoimmune diseases. This study comprises both retrospective and prospective components.
- Trial name
- NCT04558203
- Where
- Egypt
- Volunteers
- 10,510 people
- Sponsor
- ClinAmygate
Rheumatoid Arthritis (RA)
Anti-citrullinated SR-A Peptide (Anti-csp) Antibody as a Biomarker in Rheumatoid Arthritis (RA).
1. To measure serum level of anticitrullinated SR-A peptide antibody (anti-CSP) in RA patients compared to healthy controls . 2. To assess the diagnostic performance of anti-CSP for RA specifically seronegative RA patients. 3.
- Trial name
- NCT07147127
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Walaa sharif Eid Ahmed
Autoimmune Encephalitis
Neuro-ophthalmology and Autoimmune Encephalitis (NODE)
Autoimmune encephalitis represents a group of rare and heterogeneous neurological disorders. Pathophysiological mechanisms in these diseases are still unknown. Recently, oculomotor and neurovisual disorders have been described.
- Trial name
- NODE (NCT03872284)
- Testing
- oculomotor movement recordings, neurovisual assessment
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Hospices Civils de Lyon
Immune Thrombocytopenia
Low-dose Baricitinib Plus Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia
This is a prospective, multicenter, randomized, controlled phase 2 trial to compare the efficacy and safety profiles in ITP patients receiving baricitinib plus danazol to those receiving danazol alone.
- Trial name
- NCT05852847
- Testing
- Baricitinib 2 MG [Olumiant], Danazol
- Where
- 10 sites in China
- Volunteers
- 216 people
- Sponsor
- Peking University People's Hospital
Type 1 Diabetes, Type 2 Diabetes
Efficacy, Safety and Satisfaction of the New Pen Needle 33 Gauge x 4 mm.
During the last years, even more little needles are used for the injection of sub cutaneous insulin, for the diabetes therapy. The aim of this study is to evaluate the non inferiority of a new needle, smaller than another needle…
- Trial name
- AGO01 (NCT01745549)
- Testing
- Needle for insulin pen, 4 mm long and with a diameter of 33 gauge, Needle for insulin pen, 4 mm long and with a diameter of 32 gauge
- Where
- 4 sites in Italy
- Volunteers
- 87 people
- Sponsor
- Consorzio Mario Negri Sud
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