Clinical trials: Autologous Transplantation
Decayed Teeth
3D Printed Donor Tooth Replica in Autotransplantation of Teeth
3D printed replicas of the donor tooth can reduce extraoral time during the autotransplantation of teeth, which can reduce dehydration and manipulation of periodontal tissue of the donor tooth, thus possibly increasing the…
- Trial name
- NCT04933409
- Testing
- 3D printed replica of the donor tooth, Conventional Autotransplantation of tooth
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- College of Medical Sciences Teaching Hospital. Nepal
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor
Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Conditions
- Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Chordoma, Kidney Cancer
- Trial name
- NCT00003926
- Testing
- amifostine trihydrate, busulfan, filgrastim
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Alopecia, Androgenetic
STYLE -- A Trial of Cell Enriched Adipose For Androgenetic Alopecia
The primary objective of this study is to evaluate the safety and feasibility of the Celution and Puregraft Systems in the processing and preparation of an autologous fat graft enriched with adipose-derived regenerative cells…
- Trial name
- STYLE (NCT02503852)
- Testing
- Puregraft System, Celution System, Kerastem Therapy
- Where
- 4 sites in United States
- Volunteers
- 71 people
- Sponsor
- Kerastem Technologies, LLC
Multiple Myeloma, Refractory Multiple Myeloma
Plerixafor in Treating Patients With Multiple Myeloma Previously Treated With Lenalidomide and Planning to Undergo Autologous Stem Cell Transplant
Rationale: Giving colony-stimulating factors, such as G-CSF and plerixafor helps stem cells move from the patient's bone marrow to the blood so they can be collected and stored.
- Conditions
- Multiple Myeloma, Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma
- Trial name
- NCT00998049
- Testing
- plerixafor, filgrastim
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Primary Systemic Amyloidosis (AL)
Intensive Versus Conventional Treatment in Patients With Primary Amyloidosis
AL amyloidosis is caused by a clonal plasma cell dyscrasia and characterized by progressive deposition of amyloid fibrils derived from monoclonal Ig light chains, leading to multisystem organ failure and death.
- Trial name
- NCT00344526
- Testing
- Melphalan, Dexamethasone, Autologous stem cell transplantation
- Where
- 8 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Limoges
Surgical Wound, Trauma Wound
Randomized Controlled Trial to Investigate Clinical Outcomes and Associated Costs When PermeaDerm is Used as Temporary Dressing for Surgical Wounds
The goal of this study is to compare the cost and clinical outcomes for two temporary dressings (Allograft and PermeaDerm) used in patients that need a skin graft to heal their wound.
- Conditions
- Surgical Wound, Trauma Wound, Autografts, Partial-thickness Burn
- Trial name
- NCT06750809
- Testing
- PermeaDerm Biosynthetic Wound Matrix, Frozen Human Cadaveric Allograft (FHCA)
- Where
- 13 sites in United States
- Volunteers
- 40 people
- Sponsor
- Avita Medical
Primary Central Nervous System Lymphoma
Adjusted High-dose Chemotherapy With Autologous Stem Cell Transplant vs. Conventional Immunochemotherapy in Elderly PCNSL Patients
Most patients being diagnosed with primary diffuse large B-cell lymphoma of the central nervous system (PCNSL) are 60 years or older.
- Trial name
- PRIMA-CNS (NCT06830421)
- Testing
- R-MP and Procarbazine maintenance, R-MTX/AraC (MARTA) induction followed by consolidating HCT-ASCT
- Where
- 35 sites in Germany
- Volunteers
- 340 people
- Sponsor
- University Hospital Freiburg
Emphysema
Safety Study of Endobronchial Transplantation of Autologous Mesenchymal Stem Cells (MSCs) in Emphysema Patients
The purpose of this study is evaluating the safety of endobronchial transplantation of autologous mesenchymal stem cells derived bone marrow in patients with emphysema.
- Trial name
- NCT01758055
- Testing
- Autologous MSCs transplantation
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Arda Kiani
Follicular Lymphoma
Comparison of High-Dose Chemotherapy + Rituximab and CHOP + Rituximab in High-Risk Follicular Lymphoma
The purpose of this study is to determine whether an intensified treatment plus Rituximab followed by autologous transplantation is superior to a conventional chemotherapy regimen also supplemented with Rituximab.
- Trial name
- NCT00435955
- Testing
- High dose chemotherapy with autologous transplantation, Rituximab
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Liver Diseases
Autologous Bone Marrow Stem Cells Infusion for the Treatment of Liver Diseases.
This study evaluates the effect of autologous bone marrow stem cells infusion (ABMSCi) therapy for liver diseases.Treatment group will receive ABMSCi and drugs therapy ,while control group will only receive drugs therapy.
- Trial name
- ABMSCIFTLD (NCT02943707)
- Testing
- Autologous bone marrow stem cells infusion, drugs such as Ursodeoxycholic Acid tablets
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Wenzhou Medical University
Multiple Myeloma, Amyloidosis
Study of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant.
Captisol Enabled Melphalan, is a new formulation of the standard of care melphalan chemotherapy that in packaged in an inactive substance that is believed to help the chemotherapy be more stable (meaning that it doesn't lose its…
- Trial name
- NCT02909036
- Testing
- Melphalan, Pegfilgrastim, Autologous Hematopoietic Progenitor Cell Transplant
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Multiple Myeloma
S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration
Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization).
- Trial name
- DRAMMATIC (NCT04071457)
- Testing
- Lenalidomide, Daratumumab/rHuPH20
- Where
- 842 sites in United States, Canada
- Volunteers
- 1,100 people
- Sponsor
- SWOG Cancer Research Network
Multiple Myeloma
IFM 2005-01: Velcade/Dexamethasone Versus Vincristine/Adriamycin (Doxorubicin)/Dexamethasone (VAD) for the Treatment of Patients With Multiple Myeloma
This is an open-label, multi-centre, randomised Phase III study, looking at a series of 480 patients up to the age of 65 with newly diagnosed multiple myeloma (MM) not previously treated.
- Trial name
- NCT00200681
- Testing
- Velcade
- Where
- France
- Volunteers
- 493 people
- Sponsor
- Nantes University Hospital
Multiple Myeloma
Study of Carfilzomib in Multiple Myeloma Relapsed After High-dose Melphalan With Autologous Stem Cell Support
This study evaluates induction therapy with carfilzomib-cyclophosphamide-dexamethasone before salvage high-dose melphalan with autologous stem cell support (HDT) in multiple myeloma patients with relapse after HDT done at…
- Trial name
- CARFI (NCT02572492)
- Testing
- Induction with CAR-CY-DEX and conditioning with carfilzomib and highdose melphalan, Carfilzomib/dexamethasone maintenance, Observation without carfilzomib/dexamethasone maintenance
- Where
- 5 sites in Denmark, Finland and 3 more
- Volunteers
- 200 people
- Sponsor
- Henrik Gregersen
Dentine Autograft in Extraction Socket, Prf in Extraction Socket
Comparison Between Dentine Autograft VS Platelet Rich Fibrin in Extraction Socket Bone Healing
The present study will be performed to: evaluate alveolar bone healing using dentin autograft mixed with platelet-rich plasma in extraction socket vs graftless healing.
- Trial name
- NCT07798206
- Testing
- DENTION AND PRF APPLICATION IN SOCKET, PLATETELT RICH FIBRIN IN EXTRACTION SOCKET
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Multiple Myeloma
A Study to Evaluate the Long-Term Safety of Idecabtagene Vicleucel Treatment in Adults With Newly Diagnosed Multiple Myeloma in Korea
The purpose of this study is to monitor the long-term safety of participants who received idecabtagene vicleucel treatment as part of the KarMMa-9 (CA089-1043) Phase 3 clinical trial.
- Trial name
- NCT06698887
- Testing
- Idecabtagene vicleucel
- Where
- 5 sites in South Korea
- Volunteers
- 15 people
- Sponsor
- Bristol-Myers Squibb
Multiple Myeloma and Plasma Cell Neoplasm
Filgrastim Compared With Sargramostim Plus Chemotherapy, Peripheral Stem Cell Transplantation, and Interferon Alfa in Treating Patients With Multiple Myeloma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and…
- Trial name
- NCT00005987
- Testing
- carmustine, cyclophosphamide, dexamethasone
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Knee Osteoarthritis
Autologous Transplantation of Mesenchymal Stem Cells (MSCs) and Scaffold in Full-thickness Articular Cartilage
The purpose of this study is to investigate the efficacy and safety of autologous transplantation of Bone Marrow Mesenchymal stem cells (MSCs) mixed with collagen I scaffold in patient with Knee cartilage defects and…
- Trial name
- NCT00850187
- Testing
- Bone marrow derived mesenchymal stem cells
- Where
- 2 sites in Iran
- Volunteers
- 6 people
- Sponsor
- Royan Institute
Multiple Sclerosis
Autologous Hematopoietic Stem Cell Transplantation for Refractory Multiple Sclerosis
Autologous hematopoietic stem cell transplantation (aHSCT) is the only treatment for refractory autoimmune diseases capable of inducing long-term, drug-free and asymptomatic remission.
- Trial name
- NCT06228781
- Testing
- Autologous haemopoietic stem cell transplantation
- Volunteers
- 20 people
- Sponsor
- Tianjin Medical University General Hospital
T Cell Non-Hodgkin Lymphoma
A Phase 2 Multicenter Study of High Dose Chemotherapy With Autologous Stem Cell Transplant Followed by Maintenance Therapy With Romidepsin for the Treatment of T Cell Non-Hodgkin Lymphoma
The purpose of this study is to test the benefit of a chemotherapy drug called romidepsin in patients with T Cell Non-Hodgkin Lymphoma (T NHL) who have undergone autologous transplantation.
- Trial name
- NCT01908777
- Testing
- High Dose Chemotherapy with Autologous Stem Cell Transplant Followed by Maintenance Therapy with Romidepsin
- Where
- 10 sites in United States
- Volunteers
- 47 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.