Clinical trials: Automobile Driving
Alcohol Drinking, Cannabis
Effects of Inhaled Cannabis on Driving Performance
The purpose of this study is to expand understanding of the effects of cannabis on driving performance with and without the presence of low levels of alcohol.
- Trial name
- NCT01620177
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Gary R Gaffney
Acquired Brain Injury
Driving Simulator Training For Adults With Acquired Brain Injuries
The aim of this project is to prepare adults with acquired brain injuries for on-road driving by using the driving simulator and increase participant's comfort level, confidence, and independence within their occupation of…
- Trial name
- NCT07378592
- Testing
- Driving Simulation Intervention, Traditional Occupational Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sacred Heart University
Attention Deficit Hyperactivity Disorder
Enhancing ADHD Driving Performance With Stimulant Medication
Among children, attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk for accidents, especially bicycle and pedestrian (Leibson 2001; Jensen 1988; DiScala 1998).
- Trial name
- NCT00572026
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Virginia
Underage Drinking, Driving Under the Influence
Parent Intervention to Reduce College Student Drinking and Consequences
College students' alcohol use continues to be a major public health problem. Among the many consequences of this risky behavior are impaired driving and impaired passenger fatalities.
- Conditions
- Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
- Trial name
- NCT04247191
- Testing
- P-Chat, PBI, P-Chat+
- Where
- United States
- Volunteers
- 2,061 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cannabis, Alcohol Effect
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
- Conditions
- Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
- Trial name
- THC-ETOH-II (NCT02710097)
- Testing
- Active inhaled cannabis, Active Oral Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Glaucoma Eye
The Value of Visual Field Examination in Driving Licence.
The aim of the study is to identify clinical criteria, easily achievable with patient's follow-up tests, which can identify individuals at increased risk of being unfit to drive.
- Trial name
- NCT04671550
- Testing
- questionnaire
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Università degli Studi dell'Insubria
Postoperative Respiratory Complication
Driving Pressure During General Anesthesia for Open Abdominal Surgery
The purpose of this international multicenter, patient and outcome-assessor blinded randomized controlled trial is to determine whether the application of an individualized high PEEP strategy, aiming at avoiding an increase in…
- Trial name
- DESIGNATION (NCT03884543)
- Testing
- Individualized high PEEP strategy
- Where
- 22 sites in Germany, Italy and 1 more
- Volunteers
- 1,468 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pulmonary Atelectasis, Obesity, Morbid
Effects of Individualized PEEP Guided by Driving Pressure on Postoperative Atelectasis in Patients With Morbid Obesity
Atelectasis is a common complication in patients undergoing surgery under general anesthesia, particularly in obese patients. Postoperative atelectasis could last for more than 24h and contribute to a variety of other…
- Trial name
- NCT06181279
- Testing
- Individualized PEEP group, Fixed PEEP group
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Yongtao Sun
Injuries
Reducing Youthful Dangerous Driving
To examine the effectiveness of four motivational counseling groups and a directed observational experience in the emergency room in comparison to education and community volunteering only, in reducing high risk driving behaviors
- Trial name
- RYDD (NCT00852085)
- Testing
- Enhanced community service, Group MI
- Volunteers
- 482 people
- Sponsor
- Rhode Island Hospital
Dynamic Lung Compliance
Effects of Changes in Driving Pressure on Intraoperative Pulmonary Dynamic Compliance and PaO₂/FiO₂ Ratio in Laparoscopic Sleeve Gastrectomy
The goal of this prospective intervention study is to determine whether individualized positive end expiratory pressure (PEEP) titration targeting the minimum Driving pressure (ΔP) during LGS operation improves intraoperative…
- Trial name
- PEEP (NCT07494240)
- Testing
- incremental peep
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Beni-Suef University
Neurologic Disorder
Evaluation of Electric Wheelchair Driving Performance in Simulator Compared to Driving in Real-life Situations
The device that is the subject of this investigation is a solution for driving simulation of an electric wheelchair. It is intended to enable patients who are likely to acquire an electric wheelchair to train in a virtual…
- Trial name
- SIMADAPT1 (NCT04171973)
- Testing
- Driving an electric wheelchair in real condition, Driving an electric wheelchair in virtual condition
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Pôle Saint Hélier
Driving Under the Influence of Cannabis
Pilot-Study for the Comparison of Biomarkers Between Regular Cannabis Users and Non-Users
The relevance of driving under the influence of cannabis is becoming increasingly important in the context of legalization. However, the measurement of tetrahydrocannabinol (THC) blood concentration is an inadequate marker for…
- Trial name
- CANBiome (NCT06975020)
- Testing
- Participants will prepare their cannabis product ad libitum and inhale the prepared product as usual for a maximum of 15 minutes.
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Basel
Peep Titration in Lung Protective Ventilation
Lung Protective Ventilation and Driving Pressure Guided PEEP Titration in CABG Surgery
Our aim in this study is to compare fixed and individualized PEEP (driving pressure guided ) application for intraoperative lung protective ventilation in patients undergoing on-pump CABG surgery.
- Trial name
- NCT07044089
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA)
Validating a Novel Driving Simulation-based MWT Against the Standard MWT in an OSA-cohort Challenged by CPAP-withdrawal
In brief, the proposed study will evaluate a recently proposed naturalistic, driving simulation test to identify and measure sleepiness behind the wheel, one of the most underestimated causes of road accidents.
- Conditions
- Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA), CPAP Treatment, Driving Simulator Performance
- Trial name
- DS-MWT2 (NCT06872593)
- Testing
- CPAP-withdrawal, Test Sequence
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Stefan Lakämper
Lung Collapse
Open Lung Approach Versus Standard Protective Strategies
The aim of this study was to compare the effects of adding a recruitment maneuver (RM) to low tidal volume (VT) ventilation, with or without an individualized post-RM positive end-expiratory pressure (PEEP) setting in…
- Trial name
- NCT02798133
- Testing
- OLA, RM-5
- Volunteers
- 36 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Cannabis, Drug Effects, Driving Performance
Clinical Study to Evaluate the Effects of Oral Delta-9-tetrahydrocannabinol (Δ9-THC) With and Without Alcohol on Perception and Driving Performance in Healthy Adults
With the increasing prevalence and use of cannabis products by the public, there exists a need to better understand the safety impact of cannabis use, particularly when it comes to subjective perceptions of drug effect and…
- Trial name
- NCT07176208
- Testing
- 5 mg Dronabinol (Marinol®) + Alcohol Beverage, 10 mg Dronabinol (Marinol®) + Alcohol Beverage
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Food and Drug Administration (FDA)
Stroke, Driving Impaired
Fitness to Drive Among Stroke Patients
The goal of this observational study is to learn more about who can continue driving a car after a stroke. The focus of this study is on the relationship between cognitive abilities and fitness-to-drive.
- Trial name
- NCT06111989
- Testing
- Neuropsychological testing, On road test
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- National Institute for Medical Rehabilitation, Hungary
Brain Injuries, Traumatic, Concussion, Brain
Longitudinal Assessment of Post-concussion Driving in Young Adults
Upwards of 3.8 million concussions occur annually in the United States. Driving is a highly complicated activity that requires visual, motor, and cognitive skills, which are commonly impaired after concussion.
- Conditions
- Brain Injuries, Traumatic, Concussion, Brain, Brain Injury Traumatic Mild
- Trial name
- LAPDYA (NCT05942638)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Georgia
Cannabis, Alcohol Effect
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
- Conditions
- Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
- Trial name
- THC-ETOH (NCT02404688)
- Testing
- Active delta-9-THC, Active Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs)
Intraoperative Driving Pressure and Postoperative Lung Ultrasound Score in Robot-Assisted Radical Prostatectomy
The primary objective of this study is to evaluate the relationship between intraoperative driving pressure and postoperative lung ultrasound scores in patients undergoing robot-assisted laparoscopic radical prostatectomy.
- Conditions
- Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs), Prostatic Neoplams, Driving Pressure
- Trial name
- NCT07610824
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital